📄 In our new paper, we argue:
The best retrieval cue matches the memory now,
not just how it was encoded.

Always a pleasure working with @lindedomingo.bsky.social.

Amusing summary below courtesy of ChatGPT:

🔗 A synchrony bridge?
We found theta–gamma phase–amplitude coupling (TG-PAC) between hippocampus and cortex right after ripples.

TG-PAC peaks before cortical expansion, suggesting it may help coordinate the shift from compressed hippocampal codes to expanded cortical states.

🌐 After ripples, the brain’s state space unfolds.

Cortical dimensionality expands — neural patterns spread apart, making memories easier to decode.
More expansion → Faster retrieval and more reinstatement.

This raised a question:
🧠 What mechanism is driving this cortical transformation?

🧠 First, ripple characteristics:

More ripples on correct vs. incorrect trials 📈

Ripples cluster before memory responses ⏳

Timing suggests ripples help initiate retrieval, not just reflect it.

During an associative memory task, we tracked how ripple events in the hippocampus related to cortical dynamics.

🌟 Hypothesis: Ripples trigger a shift from compressed to expanded neural representations in cortex, making memories readable again.

🧠✨How do we rebuild our memories? In our new study, we show that hippocampal ripples kickstart a coordinated expansion of cortical activity that helps reconstruct past experiences.

We recorded iEEG from patients during memory retrieval... and found something really cool 👇(thread)

By examining cross-species evidence, we highlight neural mechanisms that may support episodic memory and identify crucial questions for future research.

We put forward the hypothesis of how dimensionality reduction and expansion enable the brain to encode, store and retrieve a vast amount of episodic memory information. Reduction compresses sensory input into simplified, storable codes, while expansion reconstructs vivid details.

What began as a slightly intoxicated walk on Huntington beach in California with my buddy @benjamingriffiths.bsky.social summer of 2023, ended in a published Opinion paper today in @cp-trendscognsci.bsky.social, together with Daniel Reznik and Christian Doeller at @mpicbs.bsky.social.

We put forward the hypothesis of how dimensionality reduction and expansion enable the brain to encode, store and retrieve a vast amount of episodic memory information. Reduction compresses sensory input into simplified, storable codes, while expansion reconstructs vivid details.

We put forward the hypothesis of how dimensionality reduction and expansion enable the brain to encode, store and retrieve a vast amount of episodic memory information. Reduction compresses sensory input into simplified, storable codes, while expansion reconstructs vivid details.