Canadian Journal of Ophthalmology
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Canadian Journal of Ophthalmology
@cjo-jco.bsky.social
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CJO is the official journal of the Canadian Ophthalmological Society. Publishing original, peer-reviewed articles on ophthalmology and vision science.

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Ocular tuberculosis (TB) presents diagnostic challenges, as it may mimic the appearance of other infectious and inflammatory conditions.

This article details a case of presumed ocular tuberculosis mimicking bilateral retinitis pigmentosa.

bit.ly/cjo_ocular-t...

#Ophthalmology #OcularTuberculosis
Multimodal ocular imaging for a case report on presumed ocular tuberculosis presenting as a pigmentary retinopathy published in the October 2025 issue of CJO.
November 11, 2025 at 12:13 PM
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The October issue of CJO features articles on comparing the rate of cataract surgery complications between a hospital and an independent health facility, case reports, photo essays, the F.Y. Eye column, and more.

bit.ly/cjo_60-5_Oct...

#Ophthalmology #ClinicalResearch #VisionScience
Cover for the October 2025 issue of the Canadian Journal of Ophthalmology.
November 6, 2025 at 3:21 PM
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This study compared the performance of large language models (Microsoft Copilot, GPT-4, Google Gemini) in answering 300 diverse ophthalmological questions from StatPearls, and assessed the impact of prompting techniques on their accuracy.

bit.ly/cjo_LLMs-per...
Infographic summarizing the study on the performance of large language models (Microsoft Copilot, Chat GPT-4, and Google Gemini) in answering 300 diverse ophthalmological questions from StatPearls.
August 7, 2025 at 2:31 PM
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The August CJO is now online! It features articles on translating ophthalmic medical jargon with AI, 24-hour intraocular pressure fluctuation in glaucoma patients, G-ROP versus WINROP for ROP screening, photo essays, research letters, the F.Y. Eye column, and much more.
bit.ly/cjo_60-4_Aug...
Cover of the August 2025 issue of the Canadian Journal of Ophthalmology (CJO). Cover is white with red and black text, and it features two reddish-orange fundus images on a black background in the centre-top.
July 28, 2025 at 2:12 PM
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Each relapse in acute optic neuritis results in an approximate one-line decrease in Snellen chart vision. This study found that a higher number of ipsilateral relapses is independently associated with poorer visual outcomes.

bit.ly/cjo_optic-ne...
Visual abstract infographic presents a summary of the study, including the objective, study design, methods, results, and conclusions.
June 26, 2025 at 2:13 PM
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In the United States alone, over 6 million people participate in martial arts, which are associated with injuries to the head, neck, face, and eyes. This study characterized the nature and incidence of martial arts-related eye injuries in the United States from 2012 to 2021.

bit.ly/cjo_seeing-t...
A woman in a white karate gi with a green belt strikes a punching stance in profile. One fist is held next to her face and the other fist is extended straight out in front of her. A grey, industrial-looking wall serves as the background.
June 5, 2025 at 3:32 PM
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The June CJO is now online! It features a review on integrating AI with tele-ophthalmology, articles on ocular injuries in martial arts, Langerhans cell histiocytosis of the orbit, visual recovery following pituitary adenoma surgery, the F.Y. Eye column, and more.

bit.ly/cjo_60-3_Jun...
Cover of the June 2025 issue of the CJO. The background is white. The journal name, issue, and volume appear in red and black print at the top. An picture featuring two fundus images is in the centre, and the names of three articles are featured below the image.
May 28, 2025 at 3:02 PM
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Photo essay from a teenager without surgical history who presented with decreased vision. Gene panel testing identified a heterozygous COL11A1 variant.

https://bit.ly/cjo_heterozygous-COL11A1-mutation

#Ophthalmology #COL11A1Mutation
May 21, 2025 at 11:45 AM
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Neuronal intranuclear inclusion disease is a complex neurodegenerative disorder characterized by eosinophilic intranuclear inclusions in the nervous system and visceral organ cells. This article highlights 2 cases from the same family.

bit.ly/cjo_neuronal...
Multimodal imaging from male patient. Top images show wide-field colour fundus photos. Middle images show black and white fundus autofluorescence images. Bottom images show black and white spectral-domain optical coherent tomography. Multimodal imaging from female patient. Top images show wide-field colour fundus photos. Middle images show black and white fundus autofluorescence images. Bottom images show black and white spectral-domain optical coherent tomography.
May 14, 2025 at 3:20 PM
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From a team in Alberta, this study evaluated patient satisfaction with a teleophthalmology program for ocular oncology that provides screening, remote assessment, care planning, and follow-up.

https://bit.ly/cjo_oncology-teleophthalmology

#Ophthalmology #ClinicalResearch
May 12, 2025 at 10:20 AM
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Cabozantinib is an oral tyrosine kinase receptor inhibitor used in the management of clear cell renal carcinoma. This case presents the first report of chronic recurrent conjunctival erosions secondary to cabozantinib.

bit.ly/cjo_conjunct...

#Ophthalmology
Slit lamp images showing chronic recurrent conjunctival erosions secondary to cabozantinib.
May 9, 2025 at 2:26 PM
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This review describes how high resolution OCT can be used to take “optical biopsies” that aid in the diagnosis, differentiation, and management of several benign and malignant ocular surface lesions.

bit.ly/cjo_OCT-ocul...

#Ophthalmology #ClinicalResearch
Three colour images showing eyes with different ocular surface lesions appear in a column on the left side of the image. Next to each is a corresponding black and white high-resolution optical coherence tomography image show the location of each lesion.
May 7, 2025 at 3:39 PM
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Pathological analysis from a patient with a pigmented intratarsal keratinous cyst. Intralesional cultures revealed polymicrobial colonization.

bit.ly/cjo_intratar...

#Ophthalmology
Purple pathology image showing that the cyst was limited by an outer stratified squamous epithelium with an undulating eosinophilic cuticle. Image also shows that intralesional contents included keratin and notably multiple basophilic spheric inclusions.
May 5, 2025 at 3:00 PM
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This study found that access to government-funded routine eye exams in Canada is unequal and contingent on geographical location and age. These disparities have adverse effects on Canadians’ use of eye-care providers and on their vision health outcomes.
bit.ly/cjo_access-t...
A Snellen eye chart is in the background and a pair of eye glasses are held up in front of the chart. Inside the right glasses frame, the words "eye health" appear in capital letters, clear and in focus.
May 2, 2025 at 2:46 PM
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In this study, authors evaluated the capsulorrhexis structure in 420 postmortem eyes to determine factors associated with posterior capsular opacification.

bit.ly/cjo_capsulor...

#Ophthalmology #ClinicalResearch
Collage of four Miyake-Apple view microscopic photos of postmortem eye samples in ImageJ.
April 30, 2025 at 2:56 PM
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Iris cavernous hemangioma is a rare vascular tumour that can induce spontaneous hyphema, uveitis, and glaucoma. This case of recurrent hyphema was successfully treated with iodine-125 plaque brachytherapy, and hemangioma completely resolved.

bit.ly/cjo_Iodine-1...
Collage of four images. First is slit lamp photo showing iris cavernous hemangioma in mid-iris zone. Second is ultrasound biomicroscopy of anterior chamber showing iris-related hyperecho heterogenous lesion abutting the corneal endothelium. Third is slit lamp photo 2 years after treatment showing significant resolution of the iris lesion. Fourth is slit lamp photo 7 years after treatment, showing that iris cavernous hemangioma regressed.
April 28, 2025 at 5:40 PM
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This review on ophthalmic rehabilitation in oncology care presents an overview of low vision management, ocular oncology treatments, orbital reconstructive surgery, and visual therapy for patients facing debilitating ocular sequelae due to cancer.

bit.ly/cjo_ophthalm...
Collage of images showing different ophthalmic rehabilitation materials and tools, including optical devices and tests for visual impairment; nonoptical devices for visual, orientation, and mobility training; house setup for fine motor skills, orientation, and mobility training; tactile floor and room signs; and a virtual-reality platform for children with new-onset low vision.
April 25, 2025 at 2:44 PM
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MRI scans showing increased T2 signal intensity in the right precentral gyrus and right putamen. From a case of poststrangulation hypoxic-ischemic encephalopathy with persistent cortical visual field deficits and visual hallucinations.

https://bit.ly/cjo_hypoxic-ischemic-encephalopathy
April 23, 2025 at 10:35 AM
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Our April visual abstract features a study comparing the efficiency of venturi and peristaltic pump phacoemulsification systems in patients undergoing routine laser cataract surgery.

bit.ly/cjo_venturi-...

#Ophthalmology #ClinicalResearch #CataractSurgery
Infographic describing a study that compared venturi and peristaltic based phacoemulsification efficiency in routine femtosecond laser cataract surgery. Includes the study's objective and methods, with a table summarizing the results and a brief statement about the conclusions. Infographic colours are pink, blue, black and white.
April 14, 2025 at 3:29 PM
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Corneal neovascularization and lipid keratopathy are common sequelae of interstitial keratitis. This report presents 2 cases where prolonged use of topical tacrolimus resulted in long-term resolution of these conditions.
bit.ly/cjo_corneal-...
Collage of 4 images showing 2 eyes with interstitial keratitis. The left panels show eyes with scarring over the cornea and the right panels show the same eyes after long-term treatment with tacrolimus. The scarring in both eyes is significantly reduced.
April 11, 2025 at 4:22 PM
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Conjunctival keratoacanthomas are ocular surface lesions with distinct clinical, histopathologic, and diagnostic features. This case series provides clinical, histopathological, immunohistochemical, and imaging results for this rare entity.

bit.ly/cjo_conjunct...
Collage showing examples from the conjunctival keratoacanthoma case series. Images include slit lamp photos of eyes with white lesions in the conjunctiva, high-resolution optical coherence tomography results, ultrasound biomicroscopy results, and histopathologic findings.
April 9, 2025 at 3:48 PM
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This article provides a comprehensive review of anterior uveitis epidemiology, diagnosis, and treatment, with particular emphasis on developing a tailored and stepwise strategy for the workup and treatment of anterior uveitis.

bit.ly/cjo_anterior...

#Ophthalmology #Uveitis
Close-up picture of an eye with a golden-brown iris. The white part of the eye is red and inflamed, and individual blood vessels are visible. There is also a milky-looking substance across the bottom of the iris.
April 7, 2025 at 3:04 PM
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Diabetic papillopathy is a rare complication of diabetes in children. This case reports a rare, isolated form of acute bilateral diabetic papillopathy in a 13-year-old male recently diagnosed with type 1 diabetes.

bit.ly/cjo_acute-di...

#Ophthalmology #OcularImaging #Type1Diabetes
Collage showing results from multimodal ophthalmological examination at patient's initial visit. Includes colour fundus images showing swollen optic disks and superficial telangiectatic vessels in the posterior pole in both eyes; fluorescein angiography showing telangiectasia and microvascular abnormalities and bilateral optic disc leakage and retinal staining; and optical coherence tomography confirming intraretinal macular edema.
April 1, 2025 at 2:51 PM
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April CJO is now online! It features a review on anterior uveitis for the comprehensive ophthalmologist, articles on conjunctival keratoacanthoma, digital retinoblastoma documentation, computer-aided diagnosis of eyelid skin tumors, Resident Perspectives, and more.

bit.ly/cjo_60-2_Apr...
Cover of the April 2025 issue of the CJO. It features a picture of an eye showing bilateral lens subluxation, zonular loss, and sectoral cortical opacities.
March 27, 2025 at 2:38 PM
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Our special issue contains 41 articles on personalized medicine for ocular oncology patients, including diagnostic and prognostic tools, biomarkers, predictors of treatment response, and other topics that refine an individualized approach to eye cancer care.

bit.ly/cjo_ocular-o...
Collage containing 3 images of eyes affected by different types of eye cancer.
March 26, 2025 at 3:06 PM