Cillian Gartlan
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cilliangartlan.bsky.social
Cillian Gartlan
@cilliangartlan.bsky.social
Postdoctoral Research Fellow at the Vaccine Research Center - NIAID/NIH. Opinions are my own 🇮🇪
Reposted by Cillian Gartlan
A Review in Nature provides an overview of progress and future directions in the development of nasally administered vaccines for respiratory infections. go.nature.com/44PuKMr #medsky 🧪
May 12, 2025 at 1:45 PM
Reposted by Cillian Gartlan
Happy to share a preprint from the Angelo lab many years in the making. Read on for a saga of multiplexed imaging, immunometabolism, and TB granulomas with some fun side quests into the realms of geographical information sciences and transcriptomics… (1/20) doi.org/10.1101/2025...
The immunometabolic topography of tuberculosis granulomas governs cellular organization and bacterial control
Despite being heavily infiltrated by immune cells, tuberculosis (TB) granulomas often subvert the host response to Mycobacterium tuberculosis (Mtb) infection and support bacterial persistence. We prev...
doi.org
February 24, 2025 at 10:16 PM
Reposted by Cillian Gartlan
It turns out the immune system is playing 4D chess while we thought it was just playing checkers. Using #spatialtranscriptomics from @10xgenomics.bsky.social and @vizgen.bsky.social we were able to peek into the secret lives of tissue resident T cells in the gut as they form after infection 1/n
Tissue-resident memory CD8 T cell diversity is spatiotemporally imprinted - Nature
Profiling of the location and transcriptome of tissue-resident memory CD8 T cell formation at single-transcript resolution finds regionalized signalling as the basis of immune diversity in t...
www.nature.com
January 22, 2025 at 5:37 PM