Chrysothemis Brown
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chrysothemisbrown.bsky.social
Chrysothemis Brown
@chrysothemisbrown.bsky.social
Pediatrician | Immunologist @MSK Cancer Center | Freeman Hrabowski Scholar, HHMI
www.thebrownlaboratory.com
Excited to share our review on Thetis cells and dendritic cells, and their roles in mucosal immunity and tolerance @natimmunol.nature.com rdcu.be/eLtB1
Antigen-presenting cells as arbiters of mucosal tolerance and immunity
Nature Immunology - Brown and colleagues review the heterogeneity of mucosal antigen-presenting cells that orchestrate T cell immunity to intestinal antigens.
urldefense.com
October 17, 2025 at 12:22 PM
Reposted by Chrysothemis Brown
The American Association of Immunologists AAI meeting will be in Boston, April 15-19, 2026. Come join me and @chrysothemisbrown.bsky.social at this exciting Symposium on Early life immune development. Submit your abstracts by October 15th! immunology2026.aai.org/session/earl...
Early Life Immune Development and Function   - IMMUNOLOGY2026™
Time: 8:00 - 11:30 AM Chairs: Chrysothemis C. Brown, Memorial Sloan Kettering Cancer Ctr., USA Petter Brodin, Imperial Col. London and Karolinska Inst., GBR, SWE
immunology2026.aai.org
September 22, 2025 at 3:23 PM
Thank you for the lovely write up! @mskcancercenter.bsky.social
“This is a great example of how clinical studies can reveal clues to fundamental mechanisms in biology,” says MSK's @chrysothemisbrown.bsky.social ‬. "These new understandings can pave the way for new treatment strategies for food allergies, which are desperately needed.” Learn more ⬇️
MSK Researchers Identify Key Player in Childhood Food Allergies: Thetis Cells
Thetis cells, a class of immune cells first described by MSK researchers in 2022, play an essential and previously unknown role in suppressing inflammatory responses to food, a new study finds.
www.mskcc.org
June 15, 2025 at 9:53 AM
Reposted by Chrysothemis Brown
Yep...& senior author of one,
@chrysothemisbrown.bsky.social, will be at www.emds2025.com in Edinburgh 🏴󠁧󠁢󠁳󠁣󠁴󠁿 in Sept. to discuss their work. So, if you're interested in RORgt+ APC, or APC more generally, EMDS2025 is for you!

Abstract deadline: TODAY.

@britsocimm.bsky.social @natrevimmunol.nature.com
May 30, 2025 at 11:09 AM
Excited to share our study describing a role for a subset of Thetis cells, TC IV, in tolerance to food antigens. A team effort led by Vanja Cabric and Yollanda Parisotto
www.science.org/doi/10.1126/...
A wave of Thetis cells imparts tolerance to food antigens early in life
Within the intestine, peripherally-induced regulatory T (pTreg) cells play an essential role in suppressing inflammatory responses to food proteins. However, the identity of antigen-presenting cells (...
www.science.org
May 21, 2025 at 6:24 PM
Interested in immunology and looking to gain research experience before applying to graduate or medical school?Join us! We're hiring a research technician general-mskcc.icims.com/jobs/83021/r...
Memorial Sloan Kettering Cancer Center Careers
Let’s change the way the world treats cancer Our multi-disciplinary teams work together to provide exceptional patient care, develop innovative research, and deliver outstanding educational programs.
general-mskcc.icims.com
January 8, 2025 at 9:52 AM
Reposted by Chrysothemis Brown
1/ Keen to share the story of my postdoc research out in @natureportfolio.bsky.social! We built a massive resource characterizing the spatial landscape of the gut—and yes, we dug deep into the biology too. If you’ve got a minute, let me walk you through the story. 🧵👇
www.nature.com/articles/s41...
Spatially restricted immune and microbiota-driven adaptation of the gut - Nature
Intestinal regionalization is characterized by robust and resilient structural cell states and the intestine can adapt to environmental stress in a spatially controlled manner through crosstalk betwee...
www.nature.com
November 21, 2024 at 10:21 PM