Christos Argyropoulos MD PhD
@christosargyrop.mastodon.social.ap.brid.gy
Division Chief, Nephrology, University of New Mexico
Posts: Kidney Disease, Diabetes, Transplant, COVID19, Data Science, Bioinformatics, Computing […]
🌉 bridged from https://mastodon.social/@ChristosArgyrop on the fediverse by https://fed.brid.gy/
Posts: Kidney Disease, Diabetes, Transplant, COVID19, Data Science, Bioinformatics, Computing […]
🌉 bridged from https://mastodon.social/@ChristosArgyrop on the fediverse by https://fed.brid.gy/
In #rstats, one does cut(values,breaks=c(min_value, V1,V2..,Vn,max_value),include.lowest=TRUE) to create categorical features out of continuous values.
In #perl invoke vsearch_sample ($values,$breaks), but omit the min_value from $breaks to achieve the same effect #perldatalanguage #pdl […]
In #perl invoke vsearch_sample ($values,$breaks), but omit the min_value from $breaks to achieve the same effect #perldatalanguage #pdl […]
Original post on mastodon.social
mastodon.social
December 4, 2025 at 4:18 AM
In #rstats, one does cut(values,breaks=c(min_value, V1,V2..,Vn,max_value),include.lowest=TRUE) to create categorical features out of continuous values.
In #perl invoke vsearch_sample ($values,$breaks), but omit the min_value from $breaks to achieve the same effect #perldatalanguage #pdl […]
In #perl invoke vsearch_sample ($values,$breaks), but omit the min_value from $breaks to achieve the same effect #perldatalanguage #pdl […]
Reposted by Christos Argyropoulos MD PhD
Axios: Raccoon gets drunk at Ashland ABC store and passes out in bathroom
https://www.axios.com/local/richmond/2025/12/02/drunk-raccoon-virginia-abc-store-break-in
#raccoon #animals #wildlife
https://www.axios.com/local/richmond/2025/12/02/drunk-raccoon-virginia-abc-store-break-in
#raccoon #animals #wildlife
December 2, 2025 at 11:30 PM
Axios: Raccoon gets drunk at Ashland ABC store and passes out in bathroom
https://www.axios.com/local/richmond/2025/12/02/drunk-raccoon-virginia-abc-store-break-in
#raccoon #animals #wildlife
https://www.axios.com/local/richmond/2025/12/02/drunk-raccoon-virginia-abc-store-break-in
#raccoon #animals #wildlife
Give me open access biological data to hoard for my 30TB RAID array at home.
I just finished the ENSEMBL mysql dumps (about 750GB compressed - now have to set up the mysql around 2.7TB).
GOOOOOO
I just finished the ENSEMBL mysql dumps (about 750GB compressed - now have to set up the mysql around 2.7TB).
GOOOOOO
December 3, 2025 at 2:39 AM
Give me open access biological data to hoard for my 30TB RAID array at home.
I just finished the ENSEMBL mysql dumps (about 750GB compressed - now have to set up the mysql around 2.7TB).
GOOOOOO
I just finished the ENSEMBL mysql dumps (about 750GB compressed - now have to set up the mysql around 2.7TB).
GOOOOOO
If LLMs were understood as they are ie a vector database that is searched probabilistically via levelled up Bloom filters then we would have made them more energy/compute efficient even running on the edge. Stripped of the corpo hype we could even make them ethical & useful
December 2, 2025 at 11:25 AM
If LLMs were understood as they are ie a vector database that is searched probabilistically via levelled up Bloom filters then we would have made them more energy/compute efficient even running on the edge. Stripped of the corpo hype we could even make them ethical & useful
Sometimes one has to peek under the hood or inside the black box .
How I fixed the surprisingly slow speed of the percentile function in Perl Data Language in #perl (no C)
https://chrisarg.github.io/Killing-It-with-PERL/2025/11/30/Faster-quantie-calculations-in-PDL.html
Background […]
How I fixed the surprisingly slow speed of the percentile function in Perl Data Language in #perl (no C)
https://chrisarg.github.io/Killing-It-with-PERL/2025/11/30/Faster-quantie-calculations-in-PDL.html
Background […]
Original post on mastodon.social
mastodon.social
December 1, 2025 at 12:37 PM
Sometimes one has to peek under the hood or inside the black box .
How I fixed the surprisingly slow speed of the percentile function in Perl Data Language in #perl (no C)
https://chrisarg.github.io/Killing-It-with-PERL/2025/11/30/Faster-quantie-calculations-in-PDL.html
Background […]
How I fixed the surprisingly slow speed of the percentile function in Perl Data Language in #perl (no C)
https://chrisarg.github.io/Killing-It-with-PERL/2025/11/30/Faster-quantie-calculations-in-PDL.html
Background […]
Nothing beats #perl for not disallowed data hoarding!
I may be able to finish the download of the #mysql view of Ensembl release 115 with nothing but 300 lines of #perltidy nicely formatted #Perl code.
I had not done any web automation stuff in decades but I rebounded quickly.
I may be able to finish the download of the #mysql view of Ensembl release 115 with nothing but 300 lines of #perltidy nicely formatted #Perl code.
I had not done any web automation stuff in decades but I rebounded quickly.
December 1, 2025 at 1:23 AM
The most interesting statement in that very long , information poor email is the admission that MIS-C would weigh in the decision to approve a pediatric #COVID19 vaccine.
But MIS-C is just the subacute form of the persistence related subtype of longcovid so what gives?
But MIS-C is just the subacute form of the persistence related subtype of longcovid so what gives?
November 30, 2025 at 1:37 PM
The most interesting statement in that very long , information poor email is the admission that MIS-C would weigh in the decision to approve a pediatric #COVID19 vaccine.
But MIS-C is just the subacute form of the persistence related subtype of longcovid so what gives?
But MIS-C is just the subacute form of the persistence related subtype of longcovid so what gives?
Simply beautiful
November 29, 2025 at 5:20 PM
Simply beautiful
Interesting read:
https://open.substack.com/pub/sphinxe/p/thoughts-on-konservativismus?utm_source=share&utm_medium=android&r=1tfbmy
(read the comments too).
Thoughts on "Konservativismus"
The corpse of conservatism and the online right.
https://open.substack.com/pub/sphinxe/p/thoughts-on-konservativismus?utm_source=share&utm_medium=android&r=1tfbmy
(read the comments too).
Thoughts on "Konservativismus"
The corpse of conservatism and the online right.
November 26, 2025 at 12:32 PM
Interesting read:
https://open.substack.com/pub/sphinxe/p/thoughts-on-konservativismus?utm_source=share&utm_medium=android&r=1tfbmy
(read the comments too).
Thoughts on "Konservativismus"
The corpse of conservatism and the online right.
https://open.substack.com/pub/sphinxe/p/thoughts-on-konservativismus?utm_source=share&utm_medium=android&r=1tfbmy
(read the comments too).
Thoughts on "Konservativismus"
The corpse of conservatism and the online right.
One look at the r/DataHoarder and I am surfing Seagate's data store, because setting a 32TB RAID at home and a 120TB one at work is not enough
November 25, 2025 at 9:12 PM
One look at the r/DataHoarder and I am surfing Seagate's data store, because setting a 32TB RAID at home and a 120TB one at work is not enough
I am a Bayesian but for the most part I don't mind p-values because for the common models applied in biomedicine, one can carry out a Bayesian calculation (we call those π - values with @AndrewPGrieve ) that are noncontroversial directional measures of effect
https://arxiv.org/abs/2305.00636
https://arxiv.org/abs/2305.00636
November 25, 2025 at 7:04 PM
I am a Bayesian but for the most part I don't mind p-values because for the common models applied in biomedicine, one can carry out a Bayesian calculation (we call those π - values with @AndrewPGrieve ) that are noncontroversial directional measures of effect
https://arxiv.org/abs/2305.00636
https://arxiv.org/abs/2305.00636
I just found out that one can get rid of ai slop summary in Google search by appending -ai at the end of the search string.
November 25, 2025 at 4:38 PM
I just found out that one can get rid of ai slop summary in Google search by appending -ai at the end of the search string.
Seems performance degradation is in the air.
November 25, 2025 at 2:40 PM
Seems performance degradation is in the air.
Deliberately rebuilding a 28TB RAID5 (4 X 7.2 TB HDD) to benchmark the process... it will take roughly 27 hours but will be enjoying the colors in the meantime.
(Yes, I know that my cable management sucks, this is why I didn't become a surgeon or a proceduralist)
(Yes, I know that my cable management sucks, this is why I didn't become a surgeon or a proceduralist)
November 25, 2025 at 3:50 AM
Deliberately rebuilding a 28TB RAID5 (4 X 7.2 TB HDD) to benchmark the process... it will take roughly 27 hours but will be enjoying the colors in the meantime.
(Yes, I know that my cable management sucks, this is why I didn't become a surgeon or a proceduralist)
(Yes, I know that my cable management sucks, this is why I didn't become a surgeon or a proceduralist)
November 24, 2025 at 3:08 PM
What is legacy (=I can buy it for less than $100 on eBay) GPU with good performance of integer operations ?
November 22, 2025 at 6:46 PM
What is legacy (=I can buy it for less than $100 on eBay) GPU with good performance of integer operations ?
Optimizing fun while in anticipation of receiving bad medical news around a major holiday
#nonnuanced
https://open.substack.com/pub/christosargyropoulos/p/optimizing-fun-while-receiving-bad
Summing up 3 decades in clinical practice and a #psa for all men:
sk your doctor if receiving good news […]
#nonnuanced
https://open.substack.com/pub/christosargyropoulos/p/optimizing-fun-while-receiving-bad
Summing up 3 decades in clinical practice and a #psa for all men:
sk your doctor if receiving good news […]
Original post on mastodon.social
mastodon.social
November 22, 2025 at 4:46 PM
Optimizing fun while in anticipation of receiving bad medical news around a major holiday
#nonnuanced
https://open.substack.com/pub/christosargyropoulos/p/optimizing-fun-while-receiving-bad
Summing up 3 decades in clinical practice and a #psa for all men:
sk your doctor if receiving good news […]
#nonnuanced
https://open.substack.com/pub/christosargyropoulos/p/optimizing-fun-while-receiving-bad
Summing up 3 decades in clinical practice and a #psa for all men:
sk your doctor if receiving good news […]
Who could have guessed that high dose better than low dose flu vaccination in reducing cardiovascular events?
Now do covid19 😎
Now do covid19 😎
November 20, 2025 at 3:47 PM
Who could have guessed that high dose better than low dose flu vaccination in reducing cardiovascular events?
Now do covid19 😎
Now do covid19 😎
My week-long attempt to install a functional DISA-STIG hardened RedHat Enterprise Linux had a happy ending!
#allhailubuntu
#allhailubuntu
November 19, 2025 at 2:32 AM
My week-long attempt to install a functional DISA-STIG hardened RedHat Enterprise Linux had a happy ending!
#allhailubuntu
#allhailubuntu
The AI copilot in Windows11 is going to be the mother of popcorn.
This is fresh from r/sysadmin
#canyoufeeltheagi ?
This is fresh from r/sysadmin
#canyoufeeltheagi ?
November 19, 2025 at 2:18 AM
The AI copilot in Windows11 is going to be the mother of popcorn.
This is fresh from r/sysadmin
#canyoufeeltheagi ?
This is fresh from r/sysadmin
#canyoufeeltheagi ?
About to get humiliated by DISA-STIG hardened Ubuntu
November 18, 2025 at 11:33 PM
About to get humiliated by DISA-STIG hardened Ubuntu
As it happened with the banks in 2008, the peasants will have to bail the circular financing AI bubble actors out, even if the botlicking governments have to mandate that everyone (including the unborn) are given 3 bot accounts & paid by posttax statutory paycheck deductions.
November 18, 2025 at 5:29 PM
As it happened with the banks in 2008, the peasants will have to bail the circular financing AI bubble actors out, even if the botlicking governments have to mandate that everyone (including the unborn) are given 3 bot accounts & paid by posttax statutory paycheck deductions.
Forget JSON, TOON, and VSC! The VST (Values Separated by Tabs), retains all the advantages of the VSC but brings the Pythonic esthetics to the table; a format that was stolen from the LLM gods and gifted to humans by the Prometheus (PROMpting the ETHEr for sUbStance) of the human founder spirit.
November 17, 2025 at 11:35 PM
Forget JSON, TOON, and VSC! The VST (Values Separated by Tabs), retains all the advantages of the VSC but brings the Pythonic esthetics to the table; a format that was stolen from the LLM gods and gifted to humans by the Prometheus (PROMpting the ETHEr for sUbStance) of the human founder spirit.
This piece resonated with me!
👀#Perl is a messy, maddening programming language, the “duct tape of the internet.”
✊But at least you can tell it was made by humans.
🙏Still, I find myself returning to this strange language, and I think it’s because of the humility at its core […]
👀#Perl is a messy, maddening programming language, the “duct tape of the internet.”
✊But at least you can tell it was made by humans.
🙏Still, I find myself returning to this strange language, and I think it’s because of the humility at its core […]
Original post on mastodon.social
mastodon.social
November 15, 2025 at 10:34 AM
This piece resonated with me!
👀#Perl is a messy, maddening programming language, the “duct tape of the internet.”
✊But at least you can tell it was made by humans.
🙏Still, I find myself returning to this strange language, and I think it’s because of the humility at its core […]
👀#Perl is a messy, maddening programming language, the “duct tape of the internet.”
✊But at least you can tell it was made by humans.
🙏Still, I find myself returning to this strange language, and I think it’s because of the humility at its core […]