Christian Cao
christiancao.bsky.social
Christian Cao
@christiancao.bsky.social
3rd year MD student @UofT. Fitness, music, and nature enthusiast!

Automating evidence synthesis @ ottosr.com
Our work isn’t done. We’re currently working on incorporating search and risk of bias assessments. If you’re interested in connecting, please don’t hesitate to reach out!
June 12, 2025 at 5:05 PM
... Bijan Teja; Alexander Leung; Lina Ghosn; Rahul Arora; Michael Noetel; David B. Emerson
June 12, 2025 at 5:05 PM
Plus all other researchers involved: Katherine Manta; Elina Farahani; Matthew Cecere; Anabel Selemon; Linsey Gong; Robert Kloosterman; Scott Jiang; Richard Saleh; Denis Margalik; James Lin; Jane Jomy; Jerry Xie; David Chen; Jaswanth Gorla; Sylvia Lee; Kelvin Zhang; Harriet Ware; Mairead Whelan...
June 12, 2025 at 5:04 PM
A special shout out to:
@rohitarorayyc.bsky.social
@paullusla.bsky.social
@jzsang.bsky.social

for working tirelessly to make this dream happen <3

And our advisors:
@isabelleboutron.bsky.social
David Moher
@geochurch.bsky.social
@nikbobrovitz.bsky.social
June 12, 2025 at 5:04 PM
Check out our blog post: ottosr.com/blog/announc...

Preprint: l.ottosr.com/preprint
otto-SR | The AI Systematic Review Platform
Systematic reviews in hours, not months.
ottosr.com
June 12, 2025 at 5:01 PM
If you’re a researcher who works on systematic reviews: we’re offering otto-SR through a free pilot at ottosr.com/sign-up/
otto-SR | The AI Systematic Review Platform
Systematic reviews in hours, not months.
ottosr.com
June 12, 2025 at 5:00 PM
In one review, otto-SR found 5 more relevant papers than the original authors (9 vs 4 studies).

These additional studies revealed that taking immune-enhancing nutrition before gastric surgery likely reduces hospital stay by over 1 day (p<0.05).
June 12, 2025 at 5:00 PM
When we reproduced an entire Cochrane issue of reviews (n=12 reviews), otto-SR found nearly twice as many relevant studies (n=114) compared to the original reviews (n=64).

These additional studies materially changed conclusions: two reviews became statistically significant, one lost significance.
June 12, 2025 at 5:00 PM
Through rigorous benchmarking, otto-SR consistently outperformed or matched humans in:
- screening sensitivity (otto-SR: 96.7% vs. human: 81.7%)
- screening specificity (otto-SR 97.9% vs. human 98.1%)
- data extraction accuracy (otto-SR: 93.1% vs. human: 79.7%)
June 12, 2025 at 4:58 PM