Christian Cao
christiancao.bsky.social
Christian Cao
@christiancao.bsky.social
3rd year MD student @UofT. Fitness, music, and nature enthusiast!

Automating evidence synthesis @ ottosr.com
When we reproduced an entire Cochrane issue of reviews (n=12 reviews), otto-SR found nearly twice as many relevant studies (n=114) compared to the original reviews (n=64).

These additional studies materially changed conclusions: two reviews became statistically significant, one lost significance.
June 12, 2025 at 5:00 PM
Today we’re announcing otto-SR, an AI workflow to perform systematic reviews 3000x faster

By using gpt-4.1 and o3-mini, ottoSR beats humans at all tasks

In two days, we conducted 12 work-years of Cochrane research–finding 2x more relevant papers and altering key conclusions 🧵
June 12, 2025 at 4:58 PM