Christian Heckmann
@chrismheckmann.bsky.social
Marie Skłodowska-Curie Research Fellow in Biocatalysis at TU Delft|Likes enzymes, space, and tea.
Beautiful cover art by @allisonwolder.bsky.social
On the front cover of this week's #JACS: "Asymmetric Enantio-complementary Synthesis of Thioethers via Ene-Reductase-Catalyzed C–C Bond Formation"
Read it here 🔗 buff.ly/RIVQKo0
#ChemSky
Read it here 🔗 buff.ly/RIVQKo0
#ChemSky
June 5, 2025 at 7:53 AM
Beautiful cover art by @allisonwolder.bsky.social
Reposted by Christian Heckmann
Controlling five stereocentres in one go😎 Extremely excited to finally share our work from the O’Reilly group in UCD on the assembly of chiral heterocycles via a DKR cascade🙌🏻
doi.org/10.1002/anie...
#chemistry #biocatalysis #catalysis #synthesis
doi.org/10.1002/anie...
#chemistry #biocatalysis #catalysis #synthesis
Transaminase‐Triggered Cascades for the Synthesis and Dynamic Kinetic Resolution of Chiral N‐Heterocycles
A single-step biocatalytic route to complex indolizidine and quinolizidine alkaloids is described that relies on transaminase-triggered double intramolecular aza-Michael methodology. In one case, a r...
doi.org
April 22, 2025 at 6:59 AM
Controlling five stereocentres in one go😎 Extremely excited to finally share our work from the O’Reilly group in UCD on the assembly of chiral heterocycles via a DKR cascade🙌🏻
doi.org/10.1002/anie...
#chemistry #biocatalysis #catalysis #synthesis
doi.org/10.1002/anie...
#chemistry #biocatalysis #catalysis #synthesis
Are you an early career researcher in #biocatalysis? Do you want to showcase your work to your peers? The deadline to submit an abstract for an oral presentation at #NextGenBiocat is this Sunday ⏰️. Go to nextgenbiocat.org to register.
NextGenBiocat
Visit the post for more.
nextgenbiocat.org
February 20, 2025 at 9:09 AM
Are you an early career researcher in #biocatalysis? Do you want to showcase your work to your peers? The deadline to submit an abstract for an oral presentation at #NextGenBiocat is this Sunday ⏰️. Go to nextgenbiocat.org to register.
Are you a #youngresearcher working in #biocatalysis? Do you want to share your work with #internationalscientists? Come to the #nextgenbiocat 8-9 of May in Milan! For more details on deadlines for abstract submission and how to register, see nextgenbiocat.org
NextGenBiocat
Visit the post for more.
Nextgenbiocat.org
January 30, 2025 at 1:29 PM
Are you a #youngresearcher working in #biocatalysis? Do you want to share your work with #internationalscientists? Come to the #nextgenbiocat 8-9 of May in Milan! For more details on deadlines for abstract submission and how to register, see nextgenbiocat.org
Pleased to share our pre-print on using ene reductases to synthesise chiral thioethers: doi.org/10.26434/che...
Asymmetric Enantio-Complementary Synthesis of Thioethers via Ene-Reductase Catalysed C-C bond formation
Enzymes are attractive catalysts due to their high chemo-, regio-, and enantio-selectivity. In recent years the application of enzymes in organic synthesis has expanded dramatically, especially for th...
doi.org
December 20, 2024 at 7:53 PM
Pleased to share our pre-print on using ene reductases to synthesise chiral thioethers: doi.org/10.26434/che...