@chrislinnell.bsky.social
Pinned
My first Bluesky post!
Thought I would introduce myself to begin - I'm the founder and president of the Canadian Longevity Association, which is dedicated to accelerating the introduction of effective longevity treatments and ensuring equitable access to them for all Canadians.
1/3 #longevity
Thought I would introduce myself to begin - I'm the founder and president of the Canadian Longevity Association, which is dedicated to accelerating the introduction of effective longevity treatments and ensuring equitable access to them for all Canadians.
1/3 #longevity
The latest Rejuvenation Roundup from @lifespannews.bsky.social covering the month of October is now available:
www.lifespan.io/news/rejuven...
www.lifespan.io/news/rejuven...
Rejuvenation Roundup October 2025
The trick-or-treaters have all gone home as the leaves have fallen to the ground, but rejuvenation biotech attempts to prevent human beings from fading away. Here’s what’s been done to fight aging in ...
www.lifespan.io
November 4, 2025 at 11:01 PM
The latest Rejuvenation Roundup from @lifespannews.bsky.social covering the month of October is now available:
www.lifespan.io/news/rejuven...
www.lifespan.io/news/rejuven...
The latest Rejuvenation Roundup from @lifespannews.bsky.social is now available detailing the latest advances in the longevity field.
www.lifespan.io/news/rejuven...
www.lifespan.io/news/rejuven...
August 4, 2025 at 9:11 PM
The latest Rejuvenation Roundup from @lifespannews.bsky.social is now available detailing the latest advances in the longevity field.
www.lifespan.io/news/rejuven...
www.lifespan.io/news/rejuven...
Reposted
Researchers from Laval University have found out that white collar workers who work more than 40 hours per week in midlife had higher arterial stiffness at older age as measured by carotid-femoral pulse wave velocity.
bmcpublichealth.biomedcentral.com/articles/10....
bmcpublichealth.biomedcentral.com/articles/10....
Long working hours at midlife and arterial stiffness at older age in a 24-year prospective cohort - BMC Public Health
Backgrounds This study aims to examine whether long working hours, repeatedly assessed at midlife, is associated with higher arterial stiffness at older age in a 24-year prospective study of white-col...
bmcpublichealth.biomedcentral.com
June 16, 2025 at 9:53 PM
Researchers from Laval University have found out that white collar workers who work more than 40 hours per week in midlife had higher arterial stiffness at older age as measured by carotid-femoral pulse wave velocity.
bmcpublichealth.biomedcentral.com/articles/10....
bmcpublichealth.biomedcentral.com/articles/10....
Reposted
In a large mice study, combining rapamycin and anti-cancer drug trametinib led to further lifespan extension than either drug alone.
Treatment also showed benefits against multiple age-related causes of mortality, including cancer.
www.lifespan.io/news/a-drug-...
By: @arkadimazin.bsky.social
Treatment also showed benefits against multiple age-related causes of mortality, including cancer.
www.lifespan.io/news/a-drug-...
By: @arkadimazin.bsky.social
A Drug Combo Increases Lifespan in Mice by Over 30%
Combining rapamycin with the anti-cancer drug trametinib produced a synergistic effect and robust life extension in a new study [1]. A multi-node approach […]
www.lifespan.io
June 4, 2025 at 1:24 PM
In a large mice study, combining rapamycin and anti-cancer drug trametinib led to further lifespan extension than either drug alone.
Treatment also showed benefits against multiple age-related causes of mortality, including cancer.
www.lifespan.io/news/a-drug-...
By: @arkadimazin.bsky.social
Treatment also showed benefits against multiple age-related causes of mortality, including cancer.
www.lifespan.io/news/a-drug-...
By: @arkadimazin.bsky.social
@canadianlongevity.bsky.socialMay's Rejuvenation Roundup from Lifespan.io is now available!
www.lifespan.io/news/rejuven...
www.lifespan.io/news/rejuven...
The latest longevity, life extension, and rejuvenation news.
Science is seeking to reverse human aging! We will show you how anti-aging, rejuvenation biotechnology, longevity tech, and geroscience could change the world.
Lifespan.io
June 2, 2025 at 11:06 PM
@canadianlongevity.bsky.socialMay's Rejuvenation Roundup from Lifespan.io is now available!
www.lifespan.io/news/rejuven...
www.lifespan.io/news/rejuven...
Replacing the blood or plasma in old animals with that from younger animals has shown promising results, but data from humans has so far been sparse. This small study starts to fill in that gap.
Using three different treatment regimes, including one which also included ... 1/3
Using three different treatment regimes, including one which also included ... 1/3
May 30, 2025 at 11:11 AM
Replacing the blood or plasma in old animals with that from younger animals has shown promising results, but data from humans has so far been sparse. This small study starts to fill in that gap.
Using three different treatment regimes, including one which also included ... 1/3
Using three different treatment regimes, including one which also included ... 1/3
Reposted
Researchers from Dalhousie University have discovered that senolytics can target Alzheimer’s-linked brain enzymes without harming healthy ones.
"This work provides new insight into how AD-related damage can be precisely targeted, leading the way for safer treatments that ... 1/3
"This work provides new insight into how AD-related damage can be precisely targeted, leading the way for safer treatments that ... 1/3
May 15, 2025 at 10:51 PM
Researchers from Dalhousie University have discovered that senolytics can target Alzheimer’s-linked brain enzymes without harming healthy ones.
"This work provides new insight into how AD-related damage can be precisely targeted, leading the way for safer treatments that ... 1/3
"This work provides new insight into how AD-related damage can be precisely targeted, leading the way for safer treatments that ... 1/3
Reposted
A screen of 66 medicinal agents found that apigenin, a natural flavonoid, shows both anticancer and senomorphic properties in cell culture and mice studies.
Learn more: www.lifespan.io/news/how-api...
By: Anna Drangowska-Way
Learn more: www.lifespan.io/news/how-api...
By: Anna Drangowska-Way
How Apigenin May Reduce Senescence and Cancer | Lifespan.io
Screening of a natural compounds library has revealed the senomorphic properties of apigenin. This natural flavonoid also demonstrated rejuvenating effects on many aging-associated molecular features ...
www.lifespan.io
May 14, 2025 at 4:14 PM
A screen of 66 medicinal agents found that apigenin, a natural flavonoid, shows both anticancer and senomorphic properties in cell culture and mice studies.
Learn more: www.lifespan.io/news/how-api...
By: Anna Drangowska-Way
Learn more: www.lifespan.io/news/how-api...
By: Anna Drangowska-Way
Reposted
Researchers from the CHU de Québec-Université Laval Research Center investigated the molecule SPARC, which is produced by muscles during exercise. When injected into mice it improved their muscles metabolic function, mimicking the beneficial effects of exercise. 1/2
May 12, 2025 at 8:56 PM
Researchers from the CHU de Québec-Université Laval Research Center investigated the molecule SPARC, which is produced by muscles during exercise. When injected into mice it improved their muscles metabolic function, mimicking the beneficial effects of exercise. 1/2
Anthocyanins, the blue/purple pigments found in fruit and vegetables, were found in this placebo controlled trial to reduce inflammatory markers such as CRP in adults at risk of dementia. 1/2
May 5, 2025 at 11:01 PM
Anthocyanins, the blue/purple pigments found in fruit and vegetables, were found in this placebo controlled trial to reduce inflammatory markers such as CRP in adults at risk of dementia. 1/2
Keep up your relationships! In this population-based study of immunosenescence in early midlife adults (age 33–44), it was found that "having more close friends and frequent contact related to decreased immunosenescence " and ... 1/2
April 30, 2025 at 9:01 PM
Keep up your relationships! In this population-based study of immunosenescence in early midlife adults (age 33–44), it was found that "having more close friends and frequent contact related to decreased immunosenescence " and ... 1/2
Reposted
March's Longevity Review is now out, where we will take a look at how low frequency ultrasound can reverse cellular senescence and increase mouse lifespan, as well as two studies on reducing lower back pain, the first of which uses epigenetic reprogramming, ... 1/2
youtu.be/czYRnYD4ZcI
youtu.be/czYRnYD4ZcI
March 2025 Longevity Review
YouTube video by Canadian Longevity Association
youtu.be
April 25, 2025 at 9:16 PM
March's Longevity Review is now out, where we will take a look at how low frequency ultrasound can reverse cellular senescence and increase mouse lifespan, as well as two studies on reducing lower back pain, the first of which uses epigenetic reprogramming, ... 1/2
youtu.be/czYRnYD4ZcI
youtu.be/czYRnYD4ZcI
Longevity Snapshot 11 - Senolytics to Reduce Lower Back Pain
Lower back pain is one of the most common chronic conditions of aging. In this Canadian study, senolytics were used to remove senescent cells and reduce lower back pain in mice.
www.youtube.com/watch?v=SDT0...
Lower back pain is one of the most common chronic conditions of aging. In this Canadian study, senolytics were used to remove senescent cells and reduce lower back pain in mice.
www.youtube.com/watch?v=SDT0...
Longevity Snapshot 11 - Senolytics to Reduce Lower Back Pain
YouTube video by Canadian Longevity Association
www.youtube.com
April 22, 2025 at 10:35 PM
Longevity Snapshot 11 - Senolytics to Reduce Lower Back Pain
Lower back pain is one of the most common chronic conditions of aging. In this Canadian study, senolytics were used to remove senescent cells and reduce lower back pain in mice.
www.youtube.com/watch?v=SDT0...
Lower back pain is one of the most common chronic conditions of aging. In this Canadian study, senolytics were used to remove senescent cells and reduce lower back pain in mice.
www.youtube.com/watch?v=SDT0...
Reposted
The PEARL trial tested rapamycin's effect on human healthspan and the results are in!
Read more from lead author Dr. Sajid Zalzala of AgelessRx, Ora Biomedical co-founder Matt Kaeberlein, and Lifespan.io founder @keithcomito.bsky.social:
www.lifespan.io/news/results...
By: Josh Conway
#rapamycin
Read more from lead author Dr. Sajid Zalzala of AgelessRx, Ora Biomedical co-founder Matt Kaeberlein, and Lifespan.io founder @keithcomito.bsky.social:
www.lifespan.io/news/results...
By: Josh Conway
#rapamycin
April 21, 2025 at 9:13 PM
The PEARL trial tested rapamycin's effect on human healthspan and the results are in!
Read more from lead author Dr. Sajid Zalzala of AgelessRx, Ora Biomedical co-founder Matt Kaeberlein, and Lifespan.io founder @keithcomito.bsky.social:
www.lifespan.io/news/results...
By: Josh Conway
#rapamycin
Read more from lead author Dr. Sajid Zalzala of AgelessRx, Ora Biomedical co-founder Matt Kaeberlein, and Lifespan.io founder @keithcomito.bsky.social:
www.lifespan.io/news/results...
By: Josh Conway
#rapamycin
Longevity Snapshot 10 - Reprogramming To Reduce Lower Back Pain
Lower back pain is one of the most common chronic conditions of aging. In this study epigenetic reprogramming is used to rejuvenate spinal cells and reduce lower back pain in rats.
youtu.be/JRWbyPUKp8g
Lower back pain is one of the most common chronic conditions of aging. In this study epigenetic reprogramming is used to rejuvenate spinal cells and reduce lower back pain in rats.
youtu.be/JRWbyPUKp8g
Longevity Snapshot 10 - Reprogramming To Reduce Lower Back Pain
YouTube video by Canadian Longevity Association
youtu.be
April 18, 2025 at 7:51 PM
Longevity Snapshot 10 - Reprogramming To Reduce Lower Back Pain
Lower back pain is one of the most common chronic conditions of aging. In this study epigenetic reprogramming is used to rejuvenate spinal cells and reduce lower back pain in rats.
youtu.be/JRWbyPUKp8g
Lower back pain is one of the most common chronic conditions of aging. In this study epigenetic reprogramming is used to rejuvenate spinal cells and reduce lower back pain in rats.
youtu.be/JRWbyPUKp8g
Longevity Snapshot 9 - Ultrasound for Longevity
Low frequency ultrasound was used to reverse the senescence of cells and when applied to mice led to increased physical performance, improved appearance and lengthened their lifespans.
youtu.be/TTfvtfIhoZA
Low frequency ultrasound was used to reverse the senescence of cells and when applied to mice led to increased physical performance, improved appearance and lengthened their lifespans.
youtu.be/TTfvtfIhoZA
Longevity Snapshot 9 - Ultrasound for Longevity
YouTube video by Canadian Longevity Association
youtu.be
April 15, 2025 at 9:53 PM
Longevity Snapshot 9 - Ultrasound for Longevity
Low frequency ultrasound was used to reverse the senescence of cells and when applied to mice led to increased physical performance, improved appearance and lengthened their lifespans.
youtu.be/TTfvtfIhoZA
Low frequency ultrasound was used to reverse the senescence of cells and when applied to mice led to increased physical performance, improved appearance and lengthened their lifespans.
youtu.be/TTfvtfIhoZA
Going directly from Twitter to Bluesky is like entering an alternate universe. Don't quite feel as soiled here.
April 1, 2025 at 10:01 PM
Going directly from Twitter to Bluesky is like entering an alternate universe. Don't quite feel as soiled here.
The latest longevity news for March is now available via @lifespanio.bsky.social's Rejuvenation Roundup, for which I provide a lot of the info. I've been volunteering with them since 2019!
www.lifespan.io/news/rejuven...
www.lifespan.io/news/rejuven...
The latest longevity, life extension, and rejuvenation news.
The Latest Longevity News Aging and longevity topics Editor’s Picks – The top longevity stories Industry Press Releases
Lifespan.io
April 1, 2025 at 9:12 PM
The latest longevity news for March is now available via @lifespanio.bsky.social's Rejuvenation Roundup, for which I provide a lot of the info. I've been volunteering with them since 2019!
www.lifespan.io/news/rejuven...
www.lifespan.io/news/rejuven...
The diabetes medication, metformin, was one of the first proposed longevity drugs, and was the subject of the much heralded and equally delayed TAME trial which sought to see if metformin could delay the onset of aging related diseases and thus prove the geroscience hypothesis. Despite being ... 1/4
March 28, 2025 at 3:28 PM
The diabetes medication, metformin, was one of the first proposed longevity drugs, and was the subject of the much heralded and equally delayed TAME trial which sought to see if metformin could delay the onset of aging related diseases and thus prove the geroscience hypothesis. Despite being ... 1/4
In this massive meta-analysis of 133 systematic reviews with over a quarter of a million participants, it was confirmed that exercise can improve cognition at any age.
"What this study confirms is that even low-intensity exercise -- like yoga or walking -- can improve cognition, 1/3
"What this study confirms is that even low-intensity exercise -- like yoga or walking -- can improve cognition, 1/3
March 27, 2025 at 9:26 PM
In this massive meta-analysis of 133 systematic reviews with over a quarter of a million participants, it was confirmed that exercise can improve cognition at any age.
"What this study confirms is that even low-intensity exercise -- like yoga or walking -- can improve cognition, 1/3
"What this study confirms is that even low-intensity exercise -- like yoga or walking -- can improve cognition, 1/3
A new meta-analysis of 79 studies on mortality and sleep duration found that compared to the standard range of 7-8 hours of sleep, sleeping less than 7 hours saw a 14% increase in mortality, while sleeping more than 9 hours resulted in a 34% increase in mortality.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
March 26, 2025 at 4:50 PM
A new meta-analysis of 79 studies on mortality and sleep duration found that compared to the standard range of 7-8 hours of sleep, sleeping less than 7 hours saw a 14% increase in mortality, while sleeping more than 9 hours resulted in a 34% increase in mortality.
link.springer.com/article/10.1...
link.springer.com/article/10.1...
In an observational study of over 100K adults followed for 30 years, it was found that eating healthily in mid-life was (surprise, surprise!) linked to healthier aging at 70 and 75. Healthier aging meant being free of chronic diseases, and in good mental and physical condition. More closely ... 1/3
March 24, 2025 at 8:37 PM
In an observational study of over 100K adults followed for 30 years, it was found that eating healthily in mid-life was (surprise, surprise!) linked to healthier aging at 70 and 75. Healthier aging meant being free of chronic diseases, and in good mental and physical condition. More closely ... 1/3
My first Bluesky post!
Thought I would introduce myself to begin - I'm the founder and president of the Canadian Longevity Association, which is dedicated to accelerating the introduction of effective longevity treatments and ensuring equitable access to them for all Canadians.
1/3 #longevity
Thought I would introduce myself to begin - I'm the founder and president of the Canadian Longevity Association, which is dedicated to accelerating the introduction of effective longevity treatments and ensuring equitable access to them for all Canadians.
1/3 #longevity
March 24, 2025 at 7:33 PM
My first Bluesky post!
Thought I would introduce myself to begin - I'm the founder and president of the Canadian Longevity Association, which is dedicated to accelerating the introduction of effective longevity treatments and ensuring equitable access to them for all Canadians.
1/3 #longevity
Thought I would introduce myself to begin - I'm the founder and president of the Canadian Longevity Association, which is dedicated to accelerating the introduction of effective longevity treatments and ensuring equitable access to them for all Canadians.
1/3 #longevity