HöbartnerLab UniWue
chlab.bsky.social
HöbartnerLab UniWue
@chlab.bsky.social
Nucleic Acid Chemistry Lab
Reposted by HöbartnerLab UniWue
A new paper from the Hoebartner Lab @UniWue @chlab.bsky.social reports the crystal structures of the ribozyme SAMURI, revealing the mechanism of its methyltransferase activity and site-selectivity

www.nature.com/articles/s41...
Structure and catalytic activity of the SAM-utilizing ribozyme SAMURI - Nature Chemical Biology
Crystal structures of the ribozyme SAMURI reveal the alkyltransferase mechanism and show N3-modified adenosine and dealkylated cofactor in the active site, allowing for a comparison with riboswitches ...
www.nature.com
January 14, 2025 at 5:26 PM