Chris H. Hill
@chillzaa.bsky.social
Wellcome Sir Henry Dale Fellow and PI at the University of York, UK. He/him 🏳️🌈 Interested in #RNA, #ribosomes, #cryo-EM, #crystallography and #virus gene expression, 🔬🧬
https://www.hill-lab.co.uk
Also piano 🎹🎶
www.youtube.com/@chillzaa
https://www.hill-lab.co.uk
Also piano 🎹🎶
www.youtube.com/@chillzaa
IRES domain IVc contacts uS19 and uS13 on the 'head' of the small ribosomal subunit, whilst the conserved apical GNRA tetraloop interacts directly with the initiator tRNA
October 7, 2025 at 11:37 AM
IRES domain IVc contacts uS19 and uS13 on the 'head' of the small ribosomal subunit, whilst the conserved apical GNRA tetraloop interacts directly with the initiator tRNA
In our preprint, we reconstitute human translation initiation on a model poliovirus IRES and examine 48S complexes by cryo-EM. Our structures reveal a network of interaction between IRES domain IVc and the translation machinery during start-codon recognition (closed 48S complexes)
October 7, 2025 at 11:37 AM
In our preprint, we reconstitute human translation initiation on a model poliovirus IRES and examine 48S complexes by cryo-EM. Our structures reveal a network of interaction between IRES domain IVc and the translation machinery during start-codon recognition (closed 48S complexes)
Here we present the structure of the 2A-RNA complex at 1.9 Å, revealing a novel RNA pseudoknot 👇
July 19, 2025 at 3:10 PM
Here we present the structure of the 2A-RNA complex at 1.9 Å, revealing a novel RNA pseudoknot 👇
a little É(as)tude... 🎹🐣
Happy holidays everyone!
Happy holidays everyone!
April 20, 2025 at 12:42 PM
a little É(as)tude... 🎹🐣
Happy holidays everyone!
Happy holidays everyone!