Chelsea Brown
@chelseabrown.bsky.social
Postdoctoral researcher in the Marrink lab @ Groningen University | Former member of the Stansfeld lab @ Warwick University | Views are my own | She/her 🏳️🌈
https://orcid.org/0000-0003-2006-5015
https://orcid.org/0000-0003-2006-5015
Pinned
What better way to use my first proper post than to share my first big piece of post-doctoral work with @cg-martini.bsky.social!
Here, we used integrative modelling to build and simulate a mitochondrial cristae.
Find the paper here (rdcu.be/eujAC) or see below for a quick overview 👇
Here, we used integrative modelling to build and simulate a mitochondrial cristae.
Find the paper here (rdcu.be/eujAC) or see below for a quick overview 👇
Reposted by Chelsea Brown
Kat Blow has developed CCD2MD, a suite of packages for preparing co-folded outputs for MD simulations.
Created for protein–lipid interactions in integral membrane proteins, it also works for peripheral and lipid-anchored proteins too.
pubs.acs.org/doi/full/10....
github.com/keb721/ccd2md
Created for protein–lipid interactions in integral membrane proteins, it also works for peripheral and lipid-anchored proteins too.
pubs.acs.org/doi/full/10....
github.com/keb721/ccd2md
CCD2MD: A Suite of Packages for Preparing Co-Folded Outputs for Molecular Dynamics Simulations
Protein–lipid interactions play a crucial role in the stability and function of membrane proteins. While experimental approaches to characterize these interactions in a native-like membrane environmen...
pubs.acs.org
November 12, 2025 at 11:53 AM
Kat Blow has developed CCD2MD, a suite of packages for preparing co-folded outputs for MD simulations.
Created for protein–lipid interactions in integral membrane proteins, it also works for peripheral and lipid-anchored proteins too.
pubs.acs.org/doi/full/10....
github.com/keb721/ccd2md
Created for protein–lipid interactions in integral membrane proteins, it also works for peripheral and lipid-anchored proteins too.
pubs.acs.org/doi/full/10....
github.com/keb721/ccd2md
Reposted by Chelsea Brown
Martini on top of the world ! TS2CG as a Membrane Builder | Journal of Chemical Theory and Computation pubs.acs.org/doi/10.1021/...
September 3, 2025 at 6:54 AM
Martini on top of the world ! TS2CG as a Membrane Builder | Journal of Chemical Theory and Computation pubs.acs.org/doi/10.1021/...
Reposted by Chelsea Brown
A true community effort ! The Martini 3 Lipidome: Expanded and Refined Parameters Improve Lipid Phase Behavior | ACS Central Science pubs.acs.org/doi/10.1021/...
pubs.acs.org
August 1, 2025 at 11:32 AM
A true community effort ! The Martini 3 Lipidome: Expanded and Refined Parameters Improve Lipid Phase Behavior | ACS Central Science pubs.acs.org/doi/10.1021/...
Reposted by Chelsea Brown
@chelseabrown.bsky.social @cg-martini.bsky.social@rug.nl
Integrative molecular modelling of a mitochondrial crista demonstrates a pipeline for constructing biologically representative systems and addressing interactions in complex environments
www.nature.com/articles/s42...
Integrative molecular modelling of a mitochondrial crista demonstrates a pipeline for constructing biologically representative systems and addressing interactions in complex environments
www.nature.com/articles/s42...
An integrative modelling approach to the mitochondrial cristae - Communications Biology
Integrative molecular modelling of a mitochondrial crista demonstrates a pipeline for constructing biologically representative systems and addressing interactions in complex environments.
www.nature.com
July 7, 2025 at 8:05 PM
@chelseabrown.bsky.social @cg-martini.bsky.social@rug.nl
Integrative molecular modelling of a mitochondrial crista demonstrates a pipeline for constructing biologically representative systems and addressing interactions in complex environments
www.nature.com/articles/s42...
Integrative molecular modelling of a mitochondrial crista demonstrates a pipeline for constructing biologically representative systems and addressing interactions in complex environments
www.nature.com/articles/s42...
It was great to help out the lipids with these two Mycobacterial enzymes. Fantastic work from the Mancia lab!
Also a couple of back-to-back @natcomms.nature.com papers with @chelseabrown.bsky.social on Mycobacterial enzymes in collaboration with the Mancia lab et al.: doi.org/10.1038/s414...
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Mechanistic studies of mycobacterial glycolipid biosynthesis by the mannosyltransferase PimE - Nature Communications
Here the authors investigate of the structural basis of substrate recognition and the catalytic mechanism of the mannosyltransferase PimE, which is crucial for the biosynthesis of phosphatidyl-myo-ino...
doi.org
July 8, 2025 at 5:20 AM
It was great to help out the lipids with these two Mycobacterial enzymes. Fantastic work from the Mancia lab!
What better way to use my first proper post than to share my first big piece of post-doctoral work with @cg-martini.bsky.social!
Here, we used integrative modelling to build and simulate a mitochondrial cristae.
Find the paper here (rdcu.be/eujAC) or see below for a quick overview 👇
Here, we used integrative modelling to build and simulate a mitochondrial cristae.
Find the paper here (rdcu.be/eujAC) or see below for a quick overview 👇
July 1, 2025 at 3:34 PM
What better way to use my first proper post than to share my first big piece of post-doctoral work with @cg-martini.bsky.social!
Here, we used integrative modelling to build and simulate a mitochondrial cristae.
Find the paper here (rdcu.be/eujAC) or see below for a quick overview 👇
Here, we used integrative modelling to build and simulate a mitochondrial cristae.
Find the paper here (rdcu.be/eujAC) or see below for a quick overview 👇
Reposted by Chelsea Brown
Martini workshop registration now open !!!!
See cgmartini.nl for details and how to apply.
Looking forward to seeing you in Groningen, Aug 11-15th.
See cgmartini.nl for details and how to apply.
Looking forward to seeing you in Groningen, Aug 11-15th.
May 27, 2025 at 7:55 AM
Martini workshop registration now open !!!!
See cgmartini.nl for details and how to apply.
Looking forward to seeing you in Groningen, Aug 11-15th.
See cgmartini.nl for details and how to apply.
Looking forward to seeing you in Groningen, Aug 11-15th.
Reposted by Chelsea Brown
Pre-announcement: MARTINI tutorial workshop, August 11-15th 2025 in Groningen, The Netherlands !!
Learn basic and advanced Martini from the cocktail masters themselves. Registration will open soon.
Learn basic and advanced Martini from the cocktail masters themselves. Registration will open soon.
April 28, 2025 at 9:06 AM
Pre-announcement: MARTINI tutorial workshop, August 11-15th 2025 in Groningen, The Netherlands !!
Learn basic and advanced Martini from the cocktail masters themselves. Registration will open soon.
Learn basic and advanced Martini from the cocktail masters themselves. Registration will open soon.
Reposted by Chelsea Brown
MartiniGlass: a Tool for Enabling Visualization of Coarse-Grained Martini Topologies | Journal of Chemical Information and Modeling pubs.acs.org/doi/10.1021/...
MartiniGlass: a Tool for Enabling Visualization of Coarse-Grained Martini Topologies
As molecular modeling gains ever more prominence in understanding cellular processes, high quality visualization of models and dynamics has never been more important. Naturally, much molecular visuali...
pubs.acs.org
March 26, 2025 at 7:33 PM
MartiniGlass: a Tool for Enabling Visualization of Coarse-Grained Martini Topologies | Journal of Chemical Information and Modeling pubs.acs.org/doi/10.1021/...