Chatel-Chaix Lab
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chatel-chaixlab.bsky.social
Chatel-Chaix Lab
@chatel-chaixlab.bsky.social
A research laboratory dedicated to the study of flaviviruses and SARS-CoV-2
Reposted by Chatel-Chaix Lab
Excess mitochondrial fusion is averted by stress-activated regulators, preventing the potentially harmful release of mitochondrial DNA
https://go.nature.com/3EGN5QL
Putting the brakes on mitochondrial fusion to prevent escape of mitochondrial DNA
Organelle network is regulated to prevent cellular inflammation.
go.nature.com
February 20, 2025 at 3:04 PM
Reposted by Chatel-Chaix Lab
Opportunities for CSV trainees! Apply for the CSV Lab Exchange Program to fund research collaborations or training—deadline: April 1. Details: www.csv-scv.ca/en/lab-excha...
Submit your abstract by March 1 to present at the CSV virtual seminar on April 11: forms.gle/zw2YdxQ2kLcc...
February 1, 2025 at 12:45 AM
Reposted by Chatel-Chaix Lab
We expected it to be bad, but so quickly?
This is just getting worse. All ACIP vaccine recommendations have just been taken down!

This is a massive, politically motivated crackdown and dismantling of basic public health. Vaccines save millions of lives.

This is insane.
#IDSky #PublicHealth

www.cdc.gov/acip-recs/hc...
February 1, 2025 at 1:13 PM
Reposted by Chatel-Chaix Lab
Despite carrying lethal pathogens, bats rarely develop disease — a phenomenon that has intrigued scientists for decades

https://go.nature.com/4hBWz
L0
Viral tolerance enabled by a bat-specific genomic tweak
Comparative genomics reveals how virus-carrying bats resist disease.
go.nature.com
January 29, 2025 at 9:24 PM
Reposted by Chatel-Chaix Lab
preprint advancing #flavivirus transmission understanding: 1. Flavivirus-infected #mosquito saliva always contain sfRNA inside lipide #vesicles. 2. Salivary sfRNA increases transmission by inhibiting MDA5-mediated interferon signalling.

www.biorxiv.org/content/10.1...
Multiple orthoflaviviruses secrete sfRNA in mosquito saliva to promote transmission by inhibiting MDA5-mediated early interferon response
Numerous orthoflaviviruses transmitted through the bites of different mosquito species infect more than 500 million people annually. Bite-initiated skin infection represents a critical and conserved s...
www.biorxiv.org
January 24, 2025 at 8:45 PM
Reposted by Chatel-Chaix Lab
🇭🇳 Contribute to the community
🇮🇪 Publish papers, but also be publicly visible
🇺🇸 Publication record, impact, and research quality

This is how to become a professor where you are
https://go.nature
.com/3WpESGE
Want to become a professor? Here’s how hiring criteria differ by country
Huge analysis identifies regional variations in the criteria that institutions use to move researchers up the ranks.
go.nature.com
January 22, 2025 at 4:58 PM
As a first post on Bluesky, I am very proud to share our latest research published in @cp-iscience.bsky.social on how dengue and Zika viruses hijack mitochondrial functions in respiration and apoptosis by altering their contacts with th eendoplasmic reticulum. www.sciencedirect.com/science/arti...
Dengue virus and Zika virus alter endoplasmic reticulum-mitochondria contact sites to regulate respiration and apoptosis
During infection, dengue virus (DENV) and Zika virus (ZIKV), two (ortho)flaviviruses of public health concern worldwide, induce alterations of mitocho…
www.sciencedirect.com
January 22, 2025 at 10:32 PM