Chuck Ryan
@charlesryanmd.bsky.social
Oncologist
Memorial Sloan Kettering Cancer Center
New York,NY
Memorial Sloan Kettering Cancer Center
New York,NY
This week we start a three part series on early detection- blood based, AI and EHR based, multiple cancers with one test. As the vision comes true, it promises to prevent so many early deaths. This week we talk to Nick Papadapolous from Johns Hopkins Kimmel Cancer Center
Early Detection, Part 1: Finding Cancer in the Blood, Years Before Symptoms
Podcast Episode · The Good News About Cancer · 11/04/2025 · 20m
podcasts.apple.com
November 6, 2025 at 12:16 PM
This week we start a three part series on early detection- blood based, AI and EHR based, multiple cancers with one test. As the vision comes true, it promises to prevent so many early deaths. This week we talk to Nick Papadapolous from Johns Hopkins Kimmel Cancer Center
When exercise is the prescription!
Our new podcast on a truly remarkable study in patient getting chemotherapy for colorectal cancer. More than just an improvement in outcome- it gives patients agency in their care.
podcasts.apple.com/us/podcast/t...
Our new podcast on a truly remarkable study in patient getting chemotherapy for colorectal cancer. More than just an improvement in outcome- it gives patients agency in their care.
podcasts.apple.com/us/podcast/t...
When Exercise Is The Prescription
Podcast Episode · The Good News About Cancer · 10/28/2025 · 22m
podcasts.apple.com
October 28, 2025 at 10:18 AM
When exercise is the prescription!
Our new podcast on a truly remarkable study in patient getting chemotherapy for colorectal cancer. More than just an improvement in outcome- it gives patients agency in their care.
podcasts.apple.com/us/podcast/t...
Our new podcast on a truly remarkable study in patient getting chemotherapy for colorectal cancer. More than just an improvement in outcome- it gives patients agency in their care.
podcasts.apple.com/us/podcast/t...
The Good News About Cancer is now a ‘Gold Medal Award Winner’ !
Here is season 2 episode 1 with Andrea Cercek from @mskcc.bsky.social
podcasts.apple.com/us/podcast/t...
Here is season 2 episode 1 with Andrea Cercek from @mskcc.bsky.social
podcasts.apple.com/us/podcast/t...
When Immunotherapy Can Replace Surgery
Podcast Episode · The Good News About Cancer · 10/21/2025 · 25m
podcasts.apple.com
October 22, 2025 at 2:06 PM
The Good News About Cancer is now a ‘Gold Medal Award Winner’ !
Here is season 2 episode 1 with Andrea Cercek from @mskcc.bsky.social
podcasts.apple.com/us/podcast/t...
Here is season 2 episode 1 with Andrea Cercek from @mskcc.bsky.social
podcasts.apple.com/us/podcast/t...
What could be better #GoodNewsAboutCancer than showing that healthy pregnancies with no cancer risk are possible during rx for #BreastCancer? #AnnePartridge discussed the "Positive" Study from Dana-Farber Cancer Institute on this weeks episode!
podcasts.apple.com/us/podcast/t...
podcasts.apple.com/us/podcast/t...
From Breast Cancer Patients to Healthy Mothers
Podcast Episode · The Good News About Cancer · 04/29/2025 · 22m
podcasts.apple.com
April 30, 2025 at 4:13 PM
What could be better #GoodNewsAboutCancer than showing that healthy pregnancies with no cancer risk are possible during rx for #BreastCancer? #AnnePartridge discussed the "Positive" Study from Dana-Farber Cancer Institute on this weeks episode!
podcasts.apple.com/us/podcast/t...
podcasts.apple.com/us/podcast/t...
Reposted by Chuck Ryan
1/3 Big congrats to Justin Hwang, Emmanuel Antonarakis, @charlesryanmd.bsky.social & team on a story looking at germline HSD3B1 (which is linked to prostate cancer mortality) vs. tumor findings in prostate cancer! A couple of things that I find interesting here!🧪 www.mdpi.com/2072-6694/17...
www.mdpi.com
April 9, 2025 at 11:43 AM
1/3 Big congrats to Justin Hwang, Emmanuel Antonarakis, @charlesryanmd.bsky.social & team on a story looking at germline HSD3B1 (which is linked to prostate cancer mortality) vs. tumor findings in prostate cancer! A couple of things that I find interesting here!🧪 www.mdpi.com/2072-6694/17...
Reposted by Chuck Ryan
From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA
March 22, 2025 at 10:44 AM
From 2010 to 2016 (latest data I have ), NIH research contributed to EVERY drug approved by the FDA
Reposted by Chuck Ryan
Just a reminder that when you give (or take) abiraterone for prostate cancer, you get a bunch of complex steroidal metabolites with various activities. It is messy. Below is what occurs after a single dose. 🧪
www.jci.org/articles/vie...
www.jci.org/articles/vie...
March 21, 2025 at 12:41 PM
Just a reminder that when you give (or take) abiraterone for prostate cancer, you get a bunch of complex steroidal metabolites with various activities. It is messy. Below is what occurs after a single dose. 🧪
www.jci.org/articles/vie...
www.jci.org/articles/vie...
This week we talk to Pam Munster of @ucsfcancer.bsky.social about her BRCA story and her mission to address the risk in carriers
podcasts.apple.com/us/podcast/t...
podcasts.apple.com/us/podcast/t...
Preventing Cancer by Understanding Inherited Risks
Podcast Episode · The Good News About Cancer · 03/18/2025 · 22m
podcasts.apple.com
March 18, 2025 at 11:24 AM
This week we talk to Pam Munster of @ucsfcancer.bsky.social about her BRCA story and her mission to address the risk in carriers
podcasts.apple.com/us/podcast/t...
podcasts.apple.com/us/podcast/t...
Early detection of cancer saves lives! We are getting better at this with new technology! In this weeks #Goodnewsaboutcancer we talk to Margaret Temepero of @ucsfcancer.bsky.social
podcasts.apple.com/us/podcast/t...
podcasts.apple.com/us/podcast/t...
Cancer Early Detection: Beyond Mammograms and Colonoscopy
Podcast Episode · The Good News About Cancer · 03/11/2025 · 21m
podcasts.apple.com
March 11, 2025 at 9:57 AM
Early detection of cancer saves lives! We are getting better at this with new technology! In this weeks #Goodnewsaboutcancer we talk to Margaret Temepero of @ucsfcancer.bsky.social
podcasts.apple.com/us/podcast/t...
podcasts.apple.com/us/podcast/t...
This weeks guest is Kimryn Rathmell, past Director of the National Cancer Institute (NCI) in a conversation about the wide reaching and critical role of this organization and it’s recent ‘24 in ‘24’ areas of progress! podcasts.apple.com/us/podcast/t...
The Crucial Role of the National Cancer Institute
Podcast Episode · The Good News About Cancer · 03/04/2025 · 23m
podcasts.apple.com
March 4, 2025 at 11:07 AM
This weeks guest is Kimryn Rathmell, past Director of the National Cancer Institute (NCI) in a conversation about the wide reaching and critical role of this organization and it’s recent ‘24 in ‘24’ areas of progress! podcasts.apple.com/us/podcast/t...
Proud dad moment today! Even those covering #Oscars for @apnews.com look Fab! Go Elise!
March 2, 2025 at 11:44 PM
Proud dad moment today! Even those covering #Oscars for @apnews.com look Fab! Go Elise!
This week we talk about the stunning 65% decrease in cervical cancer mortality in women under 25! The first generation of HPV vaccine recipients to reach adulthood.
Conversation with Ashish Deshmukh of MUSC
podcasts.apple.com/us/podcast/t...
Conversation with Ashish Deshmukh of MUSC
podcasts.apple.com/us/podcast/t...
Winning Against HPV
Podcast Episode · The Good News About Cancer · 02/25/2025 · 20m
podcasts.apple.com
February 25, 2025 at 7:17 PM
This week we talk about the stunning 65% decrease in cervical cancer mortality in women under 25! The first generation of HPV vaccine recipients to reach adulthood.
Conversation with Ashish Deshmukh of MUSC
podcasts.apple.com/us/podcast/t...
Conversation with Ashish Deshmukh of MUSC
podcasts.apple.com/us/podcast/t...
This week we talk to William Pao about egfr, lung cancer and his new book- Breakthrough!
The Key that Unlocked Lung Cancer
Podcast Episode · The Good News About Cancer · 02/18/2025 · 22m
podcasts.apple.com
February 18, 2025 at 11:09 AM
This week we talk to William Pao about egfr, lung cancer and his new book- Breakthrough!
Reposted by Chuck Ryan
Adrenal androgens and overall survival (OS) in men with castration-resistant prostate cancer (CRPC) treated with enzalutamide without (ENZ) or with abiraterone and prednisone (ENZ/AAP). #GU25
@charlesryanmd.bsky.social @mjmorrismd.bsky.social @ascopost.bsky.social meetings.asco.org/abstracts-pr...
@charlesryanmd.bsky.social @mjmorrismd.bsky.social @ascopost.bsky.social meetings.asco.org/abstracts-pr...
Program Guide – ASCO Meeting Program Guide
meetings.asco.org
February 14, 2025 at 5:06 AM
Adrenal androgens and overall survival (OS) in men with castration-resistant prostate cancer (CRPC) treated with enzalutamide without (ENZ) or with abiraterone and prednisone (ENZ/AAP). #GU25
@charlesryanmd.bsky.social @mjmorrismd.bsky.social @ascopost.bsky.social meetings.asco.org/abstracts-pr...
@charlesryanmd.bsky.social @mjmorrismd.bsky.social @ascopost.bsky.social meetings.asco.org/abstracts-pr...
Reposted by Chuck Ryan
Why is funding NIH so important? Listen to the Good News About Cancer w/ @charlesryanmd.bsky.social @mskcancercenter.bsky.social @drkarenknudsen.bsky.social & Dr. Morgans. Also amazing news about decline in lung cancer in Puerto Rico b/c of public health measures! podcasts.apple.com/us/podcast/4...
4.75 Million Lives Saved, and Counting
Podcast Episode · The Good News About Cancer · 02/11/2025 · 23m
podcasts.apple.com
February 15, 2025 at 9:37 PM
Why is funding NIH so important? Listen to the Good News About Cancer w/ @charlesryanmd.bsky.social @mskcancercenter.bsky.social @drkarenknudsen.bsky.social & Dr. Morgans. Also amazing news about decline in lung cancer in Puerto Rico b/c of public health measures! podcasts.apple.com/us/podcast/4...
Thank you! What an honor it was to talk about the immense influence of this remarkable person.
Chuck Ryan gives the heartfelt keynote address at the Feng Symposium. Dr. Ryan is one of the most effective communicators I’ve met. No one better to give the keynote! @ucsfcancer.bsky.social
February 13, 2025 at 10:04 PM
Thank you! What an honor it was to talk about the immense influence of this remarkable person.
Hey Bluesky friends- i’m happy to announce the launch of our new podcast – The Good News About Cancer! Did you know that there are 4.75 million Americans alive today whose lives have been saved by cancer that has been successfully treated or prevented? Lots more good news to come.
February 11, 2025 at 4:45 PM
Hey Bluesky friends- i’m happy to announce the launch of our new podcast – The Good News About Cancer! Did you know that there are 4.75 million Americans alive today whose lives have been saved by cancer that has been successfully treated or prevented? Lots more good news to come.
Reposted by Chuck Ryan
Just in time for Thanksgiving, nice pathology framework for characterizing treatment emergent neuroendocrine #ProstateCancer, a biologically diverse entity that everyone has a hard time describing, in CCR - thanks to Michael Haffner and @mishabeltran.bsky.social
aacrjournals.org/clincancerre...
aacrjournals.org/clincancerre...
Framework for the Pathology Workup of Metastatic Castration-Resistant Prostate Cancer Biopsies
Abstract. Lineage plasticity and histologic transformation from prostate adenocarcinoma to neuroendocrine prostate cancer (NEPC) occurs in up to 15-20% of patients with castration-resistant prostate c...
aacrjournals.org
November 28, 2024 at 3:16 PM
Just in time for Thanksgiving, nice pathology framework for characterizing treatment emergent neuroendocrine #ProstateCancer, a biologically diverse entity that everyone has a hard time describing, in CCR - thanks to Michael Haffner and @mishabeltran.bsky.social
aacrjournals.org/clincancerre...
aacrjournals.org/clincancerre...
Important data @ccparker.bsky.social what are your thoughts on the duration of ADT and Abi in low volume mHSPC? Data free zone but lifelong ADT may need to be rethought?
November 25, 2024 at 3:17 PM
Important data @ccparker.bsky.social what are your thoughts on the duration of ADT and Abi in low volume mHSPC? Data free zone but lifelong ADT may need to be rethought?
Always wondered whether intermittent parpi use would reduce this likelihood as well as what ‘threshold’ is required before clinical progression. Could we act at first sign of RM’s? Lots of questions .
Mechanisms of resistance to PARP inhibitors in advanced prostate cancer with BRCA2/PALB2 alterations: Reversion mutations emerge within 16 weeks. These associate with disease progression and survival.
#Cancer #Oncology @oncoalert.bsky.social @apccc.bsky.social
www.sciencedirect.com/science/arti...
#Cancer #Oncology @oncoalert.bsky.social @apccc.bsky.social
www.sciencedirect.com/science/arti...
November 23, 2024 at 5:19 PM
Always wondered whether intermittent parpi use would reduce this likelihood as well as what ‘threshold’ is required before clinical progression. Could we act at first sign of RM’s? Lots of questions .
If you see this, please repost with a favorite photo of the sky that you’ve taken recently
November 20, 2024 at 2:05 AM
Reposted by Chuck Ryan
If you see this, please repost with a favorite photo of the sky that you’ve taken recently
November 16, 2024 at 3:16 AM
If you see this, please repost with a favorite photo of the sky that you’ve taken recently