Charlène Boumendil (She/Her)
@charleneboumendil.bsky.social
Group leader @Institute of Human Genetics, chromatin lover, inclusive feminist, mother of three.
Amazing!!!!! So so well deserved! I am very happy for you. Congrats
November 7, 2025 at 1:50 PM
Amazing!!!!! So so well deserved! I am very happy for you. Congrats
Also, there is a video tutorial on how to do it, click by click so it should be very easy to implement it in every lab! I truly hope this will be helpful to the community :-)
October 7, 2025 at 7:07 PM
Also, there is a video tutorial on how to do it, click by click so it should be very easy to implement it in every lab! I truly hope this will be helpful to the community :-)
Axelle then développed a semi automated image analysis pipeline based on deep learning segmentation tools and we decided to share our detailed protocol with the community. Most of the analysis is done on Fiji (free software!) and does not require advanced bioinformatics skills.
October 7, 2025 at 7:05 PM
Axelle then développed a semi automated image analysis pipeline based on deep learning segmentation tools and we decided to share our detailed protocol with the community. Most of the analysis is done on Fiji (free software!) and does not require advanced bioinformatics skills.
One aspect we found difficult was quantification of the results, especially when it comes to relatively subtile différences. So Axelle created lentiviral vectors and stable cell lines to reduce variability (just contact us to get these!).
October 7, 2025 at 7:02 PM
One aspect we found difficult was quantification of the results, especially when it comes to relatively subtile différences. So Axelle created lentiviral vectors and stable cell lines to reduce variability (just contact us to get these!).
They are absolutely fantastic tools, one of the very few which allow to assess transport dynamics and are widely used in the nuclear pores field. As a new lab working on nuclear pores and chromatin, we had to make it work in the lab! And this was Axelle’s mission
October 7, 2025 at 6:59 PM
They are absolutely fantastic tools, one of the very few which allow to assess transport dynamics and are widely used in the nuclear pores field. As a new lab working on nuclear pores and chromatin, we had to make it work in the lab! And this was Axelle’s mission
LEXY and LINuS are optogenetics methods to assess nucleocytoplasmic transport dynamics. Original papers from di Ventura lab here: www.nature.com/articles/nco... and: www.nature.com/articles/nco...
Optogenetic control of nuclear protein export - Nature Communications
Light-inducible control of protein subcellular localization holds great promise for synthetic biology applications and insights into basic cell biology. Here the authors develop a genetically-encoded light-inducible nuclear export system and apply it to a synthetic repressor and p53 transcriptional activity.
www.nature.com
October 7, 2025 at 6:57 PM
LEXY and LINuS are optogenetics methods to assess nucleocytoplasmic transport dynamics. Original papers from di Ventura lab here: www.nature.com/articles/nco... and: www.nature.com/articles/nco...
Thank you Douaa!
September 11, 2025 at 12:16 PM
Thank you Douaa!
Fingers crossed!!! What a team!!!
September 11, 2025 at 12:16 PM
Fingers crossed!!! What a team!!!
Thank you Claire!
September 5, 2025 at 4:01 AM
Thank you Claire!
Looking forward to reading it! Congrats!
September 4, 2025 at 6:39 PM
Looking forward to reading it! Congrats!
Thanks a lot Ilya!!!
September 4, 2025 at 6:36 PM
Thanks a lot Ilya!!!
Thank you Pradeep!!
September 4, 2025 at 6:35 PM
Thank you Pradeep!!
Thanks a lot Max!
September 4, 2025 at 6:35 PM
Thanks a lot Max!
Thank you Nezha!!
September 4, 2025 at 6:35 PM
Thank you Nezha!!
Congrats!!! Very happy for you :-)
September 4, 2025 at 2:43 PM
Congrats!!! Very happy for you :-)
Very very sad today. Clarisse, you will be remembered.
August 4, 2025 at 12:17 PM
Very very sad today. Clarisse, you will be remembered.
I’m so sorry…
August 3, 2025 at 8:04 PM
I’m so sorry…