Chantelle Sephton
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chantellesephton.bsky.social
Chantelle Sephton
@chantellesephton.bsky.social
45 followers 64 following 3 posts
I am a Full Professor at Université Laval and our research focuses on understanding the complex mechanisms driving amyotrophic lateral sclerosis (ALS) and Frontotemporal dementia (FTD). For more info: https://www.sephtonlab.ca
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chantellesephton.bsky.social
🤯 www.science.org/doi/10.1126/...
A subcellular map of translational machinery composition and regulation at the single-molecule level
Millions of ribosomes are packed within mammalian cells, yet we lack tools to visualize them in toto and characterize their subcellular composition. In this study, we present ribosome expansion micros...
www.science.org
October 30, 2025 at 1:33 PM
chantellesephton.bsky.social
I am delighted to share our new publication! Huge thanks to my team and all of our outstanding co-authors for their contributions to this work: Targeting lipid droplets in FUS-linked amyotrophic lateral sclerosis mitigates neuronal and astrocytic lipotoxicity: academic.oup.com/brain/articl...
Targeting lipid droplets in FUS-linked amyotrophic lateral sclerosis mitigates neuronal and astrocytic lipotoxicity
ALS leads to loss of motor neurons, muscle atrophy and systemic energy imbalance. Marcadet and Pelaez et al. report lipid droplet accumulation and peroxida
academic.oup.com
September 24, 2025 at 2:32 PM
Reposted by Chantelle Sephton
joeallenjoe.bsky.social
In fiscal year 2024, the report found, NIH awarded more than $36.9 billion to researchers, supporting more than 408,000 jobs and generating over $94.5 billion in new economic activity nationwide.

news.harvard.edu/gazette/stor...
NIH funding delivers exponential economic returns — Harvard Gazette
Report finds all 50 states reap gains in patient health, job creation, research resources, business development.
news.harvard.edu
March 12, 2025 at 11:49 PM
Reposted by Chantelle Sephton
drddom.bsky.social
Not an article I ever expected to read...How the US is destabilizing Canada.
www.cbc.ca/news/politic...
ANALYSIS | The U.S. has covertly destabilized nations. With Canada, it's being done in public | CBC News
Former senior Canadian intelligence officials say Canada needs to be on the lookout for campaigns aimed at destabilizing the country amid U.S. President Donald Trump's escalating 51st state threats. T...
www.cbc.ca
March 12, 2025 at 8:36 PM
chantellesephton.bsky.social
Congratulations to Dr. Mari Pelaez for earning her PhD in Neuroscience at Université Laval, Canada! Check out some her published work on ALS: www.sephtonlab.ca/publications
February 13, 2025 at 10:44 PM