CGM at MGB
@cgm-mgh.bsky.social
Center for Genomic Medicine at Mass General Brigham and
Harvard Medical School
Harvard Medical School
Check out this exciting recent work from CGM PI @jorsmo.bsky.social and his colleagues in the @pgcgenetics.bsky.social!
1/4 Thrilled to be sharing new work published today in Nature describing the third wave of results from the PGC Cross-Disorder Group. This reflects a massive group effort to examine shared and unique genetic signal across >1 million cases for 14 psychiatric disorders. www.nature.com/articles/s41...
Mapping the genetic landscape across 14 psychiatric disorders - Nature
Genomic analyses applied to 14 childhood- and adult-onset psychiatric disorders identifies five underlying genomic factors that explain the majority of the genetic variance of the individual disorders...
www.nature.com
December 15, 2025 at 6:26 PM
Check out this exciting recent work from CGM PI @jorsmo.bsky.social and his colleagues in the @pgcgenetics.bsky.social!
We had such a wonderful time seeing familiar and new faces at our Center’s holiday party this week. We hope everyone enjoyed! Please tag us in your party photos- we love to see our community having fun. Thank you as always to The Liberty Hotel for hosting us!
December 12, 2025 at 3:40 PM
We had such a wonderful time seeing familiar and new faces at our Center’s holiday party this week. We hope everyone enjoyed! Please tag us in your party photos- we love to see our community having fun. Thank you as always to The Liberty Hotel for hosting us!
Don't miss the last CGM Seminar of the semester tomorrow where we'll hear from Raghu Chivukula and his lab! If you can't join us in person, join on zoom here: https://loom.ly/R-Ujl8w
December 9, 2025 at 10:15 PM
Don't miss the last CGM Seminar of the semester tomorrow where we'll hear from Raghu Chivukula and his lab! If you can't join us in person, join on zoom here: https://loom.ly/R-Ujl8w
A new multi-ancestry polygenic score for type 1 diabetes improves predictive power in non-European ancestries while maintaining high predictive power in European ancestry. Read this recent paper from Miriam Udler, Aaron Deutsch, and colleagues here!: https://loom.ly/zCRDnQQ #type1diabetes
December 8, 2025 at 4:04 PM
A new multi-ancestry polygenic score for type 1 diabetes improves predictive power in non-European ancestries while maintaining high predictive power in European ancestry. Read this recent paper from Miriam Udler, Aaron Deutsch, and colleagues here!: https://loom.ly/zCRDnQQ #type1diabetes
Don't miss Dr. Andrea Edlow and lab tomorrow at the CGM Seminar! Information below
December 2, 2025 at 8:14 PM
Don't miss Dr. Andrea Edlow and lab tomorrow at the CGM Seminar! Information below
@cgm-mgh.bsky.social faculty Chris Anderson and team found polygenic risk scores, combined w/ clinical predictors, can help identify patients most likely to develop atrial fibrillation after stroke loom.ly/QQQFp8s
February 5, 2025 at 2:02 PM
@cgm-mgh.bsky.social faculty Chris Anderson and team found polygenic risk scores, combined w/ clinical predictors, can help identify patients most likely to develop atrial fibrillation after stroke loom.ly/QQQFp8s
Reposted by CGM at MGB
🚨🚨🚨 In collaboration with @pnatarajanmd.bsky.social we are excited to launch gVasc, a new biobank focused on the genetics of spontaneous coronary artery dissection (SCAD)! with a participant-facing enrollment portal,
👉 gvascstudy.org 👈
👉 gvascstudy.org 👈
January 9, 2025 at 12:02 AM
🚨🚨🚨 In collaboration with @pnatarajanmd.bsky.social we are excited to launch gVasc, a new biobank focused on the genetics of spontaneous coronary artery dissection (SCAD)! with a participant-facing enrollment portal,
👉 gvascstudy.org 👈
👉 gvascstudy.org 👈
Reposted by CGM at MGB
A special congratulations to Konrad Karczewski, Siwei Chen, @ksamocha.bsky.social and Mike Guo for all their hard work on these publications. Read more about this work at www.nature.com/articles/d41... (2/2)
December 6, 2023 at 6:21 PM
A special congratulations to Konrad Karczewski, Siwei Chen, @ksamocha.bsky.social and Mike Guo for all their hard work on these publications. Read more about this work at www.nature.com/articles/d41... (2/2)
Reposted by CGM at MGB
🚨New paper out in Nature Mental Health from my work with @erindunnscd.bsky.social at #MassGeneral! We found that childhood adversity leads to #epigenetic changes that can increase OR reduce risk for depression. Let me explain... 🧵(1/6)
Read the paper here: www.nature.com/articles/s44...
Read the paper here: www.nature.com/articles/s44...
December 2, 2024 at 8:11 PM
🚨New paper out in Nature Mental Health from my work with @erindunnscd.bsky.social at #MassGeneral! We found that childhood adversity leads to #epigenetic changes that can increase OR reduce risk for depression. Let me explain... 🧵(1/6)
Read the paper here: www.nature.com/articles/s44...
Read the paper here: www.nature.com/articles/s44...
Researchers @TalkowskiLab used long-read sequencing and the T2T reference to characterize previously intractable genome rearrangements (e.g. ring chroms, Robertsonian translocations), shining light on their formation and consequences. @ajhgnews.bsky.social www.sciencedirect.com/science/arti...
Resolution of ring chromosomes, Robertsonian translocations, and complex structural variants from long-read sequencing and telomere-to-telomere assembly
Delineation of structural variants (SVs) at sequence resolution in highly repetitive genomic regions has long been intractable. The sequence propertie…
www.sciencedirect.com
January 29, 2025 at 5:10 PM
Researchers @TalkowskiLab used long-read sequencing and the T2T reference to characterize previously intractable genome rearrangements (e.g. ring chroms, Robertsonian translocations), shining light on their formation and consequences. @ajhgnews.bsky.social www.sciencedirect.com/science/arti...