Sally Lowell
@cellysally.bsky.social
Developmental & stem cell biologist, University of Edinburgh
Digs repetition
Also digs local coordination between cells in development and disease
#SustainableConferencing #Music #Science #MoreScience
Mastodon @CellySally@biologists.social
Digs repetition
Also digs local coordination between cells in development and disease
#SustainableConferencing #Music #Science #MoreScience
Mastodon @CellySally@biologists.social
Pinned
Sally Lowell
@cellysally.bsky.social
· Sep 16
As summer ends, puffins leave Scotland and migrate long distances, heading west across the Atlantic, or south to Africa, and with some individuals venturing into the Mediterranean Sea
This one ended up on the cover of today's EMBO Journal 😃
#GotTheCover
www.embopress.org/toc/14602075...
This one ended up on the cover of today's EMBO Journal 😃
#GotTheCover
www.embopress.org/toc/14602075...
Reposted by Sally Lowell
🌱During #COP30, we invite you to explore what is the carbon footprint of an event and learn about easy steps to take to minimise it.
🟢Learn more with our free event carbon calculator: biologists.com/sustainabili...
🟢Learn more with our free event carbon calculator: biologists.com/sustainabili...
November 14, 2025 at 10:26 AM
🌱During #COP30, we invite you to explore what is the carbon footprint of an event and learn about easy steps to take to minimise it.
🟢Learn more with our free event carbon calculator: biologists.com/sustainabili...
🟢Learn more with our free event carbon calculator: biologists.com/sustainabili...
Reposted by Sally Lowell
Development that lasts a life time. Check out the 2025 special issue of @dev-journal.bsky.social on Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues
journals.biologists.com/dev/issue/15...
journals.biologists.com/dev/issue/15...
Volume 152 Issue 20 | Development | The Company of Biologists
journals.biologists.com
November 5, 2025 at 8:54 AM
Development that lasts a life time. Check out the 2025 special issue of @dev-journal.bsky.social on Lifelong Development: the Maintenance, Regeneration and Plasticity of Tissues
journals.biologists.com/dev/issue/15...
journals.biologists.com/dev/issue/15...
It was such a pleasure to host @joadelas.bsky.social at @edinuni-irr.bsky.social yesterday. What a great talk- fascinating insights into how Cis Regulatory Elements process spatial and temporal information to build complicated and beautiful things such as embryos. Bravo Joaquina!
Go to sleep in London, wake up in Edinburg! Great experience aboard the Caledonian Sleeper train.
Looking forward to a fun day full of science at the CRM. Thank you so much @cellysally.bsky.social for hosting me.
Looking forward to a fun day full of science at the CRM. Thank you so much @cellysally.bsky.social for hosting me.
October 31, 2025 at 9:06 AM
It was such a pleasure to host @joadelas.bsky.social at @edinuni-irr.bsky.social yesterday. What a great talk- fascinating insights into how Cis Regulatory Elements process spatial and temporal information to build complicated and beautiful things such as embryos. Bravo Joaquina!
Reposted by Sally Lowell
Go to sleep in London, wake up in Edinburg! Great experience aboard the Caledonian Sleeper train.
Looking forward to a fun day full of science at the CRM. Thank you so much @cellysally.bsky.social for hosting me.
Looking forward to a fun day full of science at the CRM. Thank you so much @cellysally.bsky.social for hosting me.
October 30, 2025 at 8:08 AM
Go to sleep in London, wake up in Edinburg! Great experience aboard the Caledonian Sleeper train.
Looking forward to a fun day full of science at the CRM. Thank you so much @cellysally.bsky.social for hosting me.
Looking forward to a fun day full of science at the CRM. Thank you so much @cellysally.bsky.social for hosting me.
Reposted by Sally Lowell
Read the 1st prize winning essay from our competition 'Innovative ideas for the future of sustainable events'. Read Liew Yao Rong’s essay and learn about his innovative approach that combines participants’ management, location and logistics: www.biologists.com/stories/peop...
October 28, 2025 at 8:15 AM
Read the 1st prize winning essay from our competition 'Innovative ideas for the future of sustainable events'. Read Liew Yao Rong’s essay and learn about his innovative approach that combines participants’ management, location and logistics: www.biologists.com/stories/peop...
Reposted by Sally Lowell
Thank you @scholarlykitchen.bsky.social for featuring our Event Carbon Calculator in your article.
Read more for many great #sustainability tips.
Read more for many great #sustainability tips.
Five Tips for Hosting a Sustainable Event scholarlykitchen.sspnet.org/2025/10/14/f...
Five Tips for Hosting a Sustainable Event - The Scholarly Kitchen
Event planners are faced with the delicate balance between constructing spaces for deeper connection with the impact we’re having on our planet. Here’s what I’ve learned about planning events that pri...
scholarlykitchen.sspnet.org
October 28, 2025 at 10:59 AM
Thank you @scholarlykitchen.bsky.social for featuring our Event Carbon Calculator in your article.
Read more for many great #sustainability tips.
Read more for many great #sustainability tips.
Reposted by Sally Lowell
“Developmental biology is fundamentally beautiful. We are no less beautiful for our variation. Instead, perhaps we are more so. Perhaps we are remarkable. Perhaps we are full of wonder.”
Read this insightful post by Bethan on the Node.
thenode.biologists.com/developmenta...
#Disability
Read this insightful post by Bethan on the Node.
thenode.biologists.com/developmenta...
#Disability
Developmental Biology and Disability - the Node
Hopeful monsters. Morphospace. Mutation. Natural variation. Mutagenesis screens. Polymorphism. Deformity. Phenotype. Disease. Adaptation. Anomaly.
thenode.biologists.com
October 22, 2025 at 1:15 PM
“Developmental biology is fundamentally beautiful. We are no less beautiful for our variation. Instead, perhaps we are more so. Perhaps we are remarkable. Perhaps we are full of wonder.”
Read this insightful post by Bethan on the Node.
thenode.biologists.com/developmenta...
#Disability
Read this insightful post by Bethan on the Node.
thenode.biologists.com/developmenta...
#Disability
The Possible vs. The Actual: can #GenerativeBiology reveal fundamental design principles of complex life?
@philipcball.bsky.social closes #GenBio25 with a magnificent synthesis of the past two days of discussions, and guides us towards an agenda for the future of the field.
@philipcball.bsky.social closes #GenBio25 with a magnificent synthesis of the past two days of discussions, and guides us towards an agenda for the future of the field.
October 21, 2025 at 5:43 PM
The Possible vs. The Actual: can #GenerativeBiology reveal fundamental design principles of complex life?
@philipcball.bsky.social closes #GenBio25 with a magnificent synthesis of the past two days of discussions, and guides us towards an agenda for the future of the field.
@philipcball.bsky.social closes #GenBio25 with a magnificent synthesis of the past two days of discussions, and guides us towards an agenda for the future of the field.
Reposted by Sally Lowell
Good afternoon #GenBio25. @bensteventon.bsky.social uses a flock of sheep as an analogy for multi-level reciprocal interactions between cells and how to engineer them.
a herd of sheep walking down a grassy path
ALT: a herd of sheep walking down a grassy path
media.tenor.com
October 20, 2025 at 12:53 PM
Good afternoon #GenBio25. @bensteventon.bsky.social uses a flock of sheep as an analogy for multi-level reciprocal interactions between cells and how to engineer them.
Reposted by Sally Lowell
Who are our (cellular) neighbours? @matt-mala.bsky.social is addressing this question now at #GenBio25, using characters living on a conceptual ‘Cell Street’. Learn more in his @dev-journal.bsky.social Primer: doi.org/10.1242/dev....
Enabling neighbour labelling: using synthetic biology to explore how cells influence their neighbours
Summary: This Primer reviews emerging approaches for engineering synthetic signalling between cells and discusses how these could be applied to study the influence cells have on their neighbours durin...
doi.org
October 20, 2025 at 8:44 AM
Who are our (cellular) neighbours? @matt-mala.bsky.social is addressing this question now at #GenBio25, using characters living on a conceptual ‘Cell Street’. Learn more in his @dev-journal.bsky.social Primer: doi.org/10.1242/dev....
Reposted by Sally Lowell
Good morning from Generative Biology! @bernasozen.bsky.social starts by taking a closer look at metabolism in early embryogenesis.
Learn more about stem cell-based embryo models in her recent @dev-journal.bsky.social Review: doi.org/10.1242/dev.... and interview: doi.org/10.1242/dev....
Learn more about stem cell-based embryo models in her recent @dev-journal.bsky.social Review: doi.org/10.1242/dev.... and interview: doi.org/10.1242/dev....
Transitions in development – an interview with Berna Sozen
Berna Sozen is an Assistant Professor in the Department of Genetics at Yale University, USA. Berna's lab studies early mammalian development, metabolism, and maternal–fetal interactions using mouse an...
doi.org
October 20, 2025 at 8:12 AM
Good morning from Generative Biology! @bernasozen.bsky.social starts by taking a closer look at metabolism in early embryogenesis.
Learn more about stem cell-based embryo models in her recent @dev-journal.bsky.social Review: doi.org/10.1242/dev.... and interview: doi.org/10.1242/dev....
Learn more about stem cell-based embryo models in her recent @dev-journal.bsky.social Review: doi.org/10.1242/dev.... and interview: doi.org/10.1242/dev....
Reposted by Sally Lowell
Three short talks now at #GenBio25. @bracciolilab.bsky.social discusses the ability of cells to contribute to different lineages in a gastruloid model. Luca recently published an ‘In preprints’ article in @dev-journal.bsky.social: doi.org/10.1242/dev....
October 20, 2025 at 10:57 AM
Three short talks now at #GenBio25. @bracciolilab.bsky.social discusses the ability of cells to contribute to different lineages in a gastruloid model. Luca recently published an ‘In preprints’ article in @dev-journal.bsky.social: doi.org/10.1242/dev....
We are looking forward to spending the next two days discussing INTERESTING THINGS at our workshop on Generative Biology: new approaches to study developmental design principles #GenBio25
Thanks to my excellent coorganisers @jcornwallscoones.bsky.social & @dbenzinger.bsky.social & all participants
Thanks to my excellent coorganisers @jcornwallscoones.bsky.social & @dbenzinger.bsky.social & all participants
En route to Brighton—for the 1st time—for the @royalsociety.org Generative Biology meeting organised by @jcornwallscoones.bsky.social, @dbenzinger.bsky.social & @cellysally.bsky.social. Happy to chat about @dev-journal.bsky.social, @the-node.bsky.social & @biologists.bsky.social. Also have freebies!
October 19, 2025 at 5:00 PM
We are looking forward to spending the next two days discussing INTERESTING THINGS at our workshop on Generative Biology: new approaches to study developmental design principles #GenBio25
Thanks to my excellent coorganisers @jcornwallscoones.bsky.social & @dbenzinger.bsky.social & all participants
Thanks to my excellent coorganisers @jcornwallscoones.bsky.social & @dbenzinger.bsky.social & all participants
Reposted by Sally Lowell
BREAKING🚨: @Equinor has resubmitted its application to open the biggest undeveloped oil field in the UK - Rosebank.
In the next weeks, the UK gov will decide to reject or approve this disaster project.
Equinor hasn’t given up, and neither will we. We’re stepping things up.
In the next weeks, the UK gov will decide to reject or approve this disaster project.
Equinor hasn’t given up, and neither will we. We’re stepping things up.
October 15, 2025 at 11:26 AM
BREAKING🚨: @Equinor has resubmitted its application to open the biggest undeveloped oil field in the UK - Rosebank.
In the next weeks, the UK gov will decide to reject or approve this disaster project.
Equinor hasn’t given up, and neither will we. We’re stepping things up.
In the next weeks, the UK gov will decide to reject or approve this disaster project.
Equinor hasn’t given up, and neither will we. We’re stepping things up.
Reposted by Sally Lowell
With storm Amy approaching, it’s an ideal time to get your SLiPERs on!
Hot off the press!
Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4
www.nature.com/articles/s41...
Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4
www.nature.com/articles/s41...
Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4 - Nature Communications
Here they perform a systematic dissection of OCT4 and reveal how intrinsically disordered regions can be used to serve specific functions during reprogramming and embryonic development. This can be exploited to engineer more efficient and specific reprogramming factors.
www.nature.com
October 3, 2025 at 3:38 PM
With storm Amy approaching, it’s an ideal time to get your SLiPERs on!
Hot off the press!
Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4
www.nature.com/articles/s41...
Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4
www.nature.com/articles/s41...
Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4 - Nature Communications
Here they perform a systematic dissection of OCT4 and reveal how intrinsically disordered regions can be used to serve specific functions during reprogramming and embryonic development. This can be exploited to engineer more efficient and specific reprogramming factors.
www.nature.com
September 30, 2025 at 4:16 PM
Hot off the press!
Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4
www.nature.com/articles/s41...
Cell-type-specific functionality encoded within the intrinsically disordered regions of OCT4
www.nature.com/articles/s41...
Reposted by Sally Lowell
Nice work from Val Wilson & co on neuromesodermal progenitors
SOX2/TBXT co-expressing cells are self-propagating bipotent NMPs
Increasing TBXT levels (not SOX2/TBXT ratio) switch NMPs from neural- to mesoderm-biased
www.biorxiv.org/content/10.1...
SOX2/TBXT co-expressing cells are self-propagating bipotent NMPs
Increasing TBXT levels (not SOX2/TBXT ratio) switch NMPs from neural- to mesoderm-biased
www.biorxiv.org/content/10.1...
Brachyury expression levels predict lineage potential and axis-forming ability of in vitro derived neuromesodermal progenitors
Neuromesodermal progenitors (NMPs) produce the spinal cord and musculoskeleton in the elongating anterior-posterior axis. In vivo, NMPs possess dual potency, coinciding with regions coexpressing SOX2 ...
www.biorxiv.org
September 29, 2025 at 8:33 AM
Nice work from Val Wilson & co on neuromesodermal progenitors
SOX2/TBXT co-expressing cells are self-propagating bipotent NMPs
Increasing TBXT levels (not SOX2/TBXT ratio) switch NMPs from neural- to mesoderm-biased
www.biorxiv.org/content/10.1...
SOX2/TBXT co-expressing cells are self-propagating bipotent NMPs
Increasing TBXT levels (not SOX2/TBXT ratio) switch NMPs from neural- to mesoderm-biased
www.biorxiv.org/content/10.1...
Reposted by Sally Lowell
Ever thought about exploring Stem Cells in different fields of biomedical research while surrounded by the beauty of a Greek island? That's exactly what the European Stem Cell Summer School offers – an inspiring learning experience on the outstanding island of Spetses 🇬🇷 @stemcellsummer.bsky.social
September 21, 2025 at 11:47 AM
Ever thought about exploring Stem Cells in different fields of biomedical research while surrounded by the beauty of a Greek island? That's exactly what the European Stem Cell Summer School offers – an inspiring learning experience on the outstanding island of Spetses 🇬🇷 @stemcellsummer.bsky.social
Reposted by Sally Lowell
An image analysis toolkit to streamline the study of cell fates in embryo development
Image made with @leicamicrosystems.bsky.social microscopy
📷 Matthew French et al @cellysally.bsky.social lab University of Edinburgh in @plosbiology.org
➡️ bpod.org.uk/archive/2025...
Image made with @leicamicrosystems.bsky.social microscopy
📷 Matthew French et al @cellysally.bsky.social lab University of Edinburgh in @plosbiology.org
➡️ bpod.org.uk/archive/2025...
September 16, 2025 at 4:30 PM
An image analysis toolkit to streamline the study of cell fates in embryo development
Image made with @leicamicrosystems.bsky.social microscopy
📷 Matthew French et al @cellysally.bsky.social lab University of Edinburgh in @plosbiology.org
➡️ bpod.org.uk/archive/2025...
Image made with @leicamicrosystems.bsky.social microscopy
📷 Matthew French et al @cellysally.bsky.social lab University of Edinburgh in @plosbiology.org
➡️ bpod.org.uk/archive/2025...
Very excited to have this back-end-of-an-embryo cell-neighbour-analysis image from our latest paper featured as today's Biomedical Image of the Day!
Congrats to first author and ace image-analyst Matthew French
bpod.org.uk/archive/2025...
Congrats to first author and ace image-analyst Matthew French
bpod.org.uk/archive/2025...
BPoD | Following Fate
Following Fate - Biomedical pictures for September 2025.
bpod.org.uk
September 16, 2025 at 12:29 PM
Very excited to have this back-end-of-an-embryo cell-neighbour-analysis image from our latest paper featured as today's Biomedical Image of the Day!
Congrats to first author and ace image-analyst Matthew French
bpod.org.uk/archive/2025...
Congrats to first author and ace image-analyst Matthew French
bpod.org.uk/archive/2025...
Reposted by Sally Lowell
👀 Do you have an idea for a post on the Node that you have been postponing writing for a while? This is your chance to publish your piece at last for a chance to win £200. Submit your post by 30 September 2025. 📝
thenode.biologists.com/the-node-wri...
#devbio #stemcell
thenode.biologists.com/the-node-wri...
#devbio #stemcell
September 16, 2025 at 12:16 PM
👀 Do you have an idea for a post on the Node that you have been postponing writing for a while? This is your chance to publish your piece at last for a chance to win £200. Submit your post by 30 September 2025. 📝
thenode.biologists.com/the-node-wri...
#devbio #stemcell
thenode.biologists.com/the-node-wri...
#devbio #stemcell
Reposted by Sally Lowell
The Scientific Distillery
Could you distil a complex scientific concept so that it can be explained in 30 seconds and be understood by a lay person, but *without* sacrificing scientific depth?
The delegates at #SCSS2025 were brilliant at this task 👏
Could you distil a complex scientific concept so that it can be explained in 30 seconds and be understood by a lay person, but *without* sacrificing scientific depth?
The delegates at #SCSS2025 were brilliant at this task 👏
September 16, 2025 at 10:44 AM
The Scientific Distillery
Could you distil a complex scientific concept so that it can be explained in 30 seconds and be understood by a lay person, but *without* sacrificing scientific depth?
The delegates at #SCSS2025 were brilliant at this task 👏
Could you distil a complex scientific concept so that it can be explained in 30 seconds and be understood by a lay person, but *without* sacrificing scientific depth?
The delegates at #SCSS2025 were brilliant at this task 👏
Austin Smith points out that naive pluripotent cells in the embryo only self- renew rarely, if ever.
In response to some heckling from the faculty, he says “You can call ES cells artifacts if you want, but they’re still bloody marvellous” 😃
#SCSS2025
In response to some heckling from the faculty, he says “You can call ES cells artifacts if you want, but they’re still bloody marvellous” 😃
#SCSS2025
September 14, 2025 at 8:56 AM
Austin Smith points out that naive pluripotent cells in the embryo only self- renew rarely, if ever.
In response to some heckling from the faculty, he says “You can call ES cells artifacts if you want, but they’re still bloody marvellous” 😃
#SCSS2025
In response to some heckling from the faculty, he says “You can call ES cells artifacts if you want, but they’re still bloody marvellous” 😃
#SCSS2025
Reposted by Sally Lowell
A provocative opening this morning from Cedric Blanpain, who sets out to argue that most tissues are maintained by unipotent stem cells. We look forward to hearing him make his case.. #SCSS2025
September 14, 2025 at 6:09 AM
A provocative opening this morning from Cedric Blanpain, who sets out to argue that most tissues are maintained by unipotent stem cells. We look forward to hearing him make his case.. #SCSS2025