We show how translation initiation & elongation rates are tightly coupled in mammalian cells using single-molecule SunTag imaging & a TASEP-based modeling framework. This coordination keeps ribosome density low, even under eIF5A inhibition or knockout!
shorturl.at/6vuQP
We show how translation initiation & elongation rates are tightly coupled in mammalian cells using single-molecule SunTag imaging & a TASEP-based modeling framework. This coordination keeps ribosome density low, even under eIF5A inhibition or knockout!
shorturl.at/6vuQP
We’re excited to share two complementary studies built on a shared dataset, exploring how cells regulate translation elongation under amino acid starvation, from computational and biological angles.
🧠 + 🧬 = 🔬💥
Read on 👇
We’re excited to share two complementary studies built on a shared dataset, exploring how cells regulate translation elongation under amino acid starvation, from computational and biological angles.
🧠 + 🧬 = 🔬💥
Read on 👇