Nayan Arora
@captainchloride.bsky.social
Associate Professor and APD @pdxkidney.bsky.social | Cardiorenal enthusiast | Whisky drinker, runner, dad | Filtrate on Freely Filtered 🎙️
We are 2 for 2 with positive trials so far. LIBERATE-D shows benefit with a conservative vs conventional dialysis strategy in AKI-D. The difference in mortality is concerning though? Simultaneous pub 👇🏾 #kidneywk
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
November 7, 2025 at 5:10 PM
We are 2 for 2 with positive trials so far. LIBERATE-D shows benefit with a conservative vs conventional dialysis strategy in AKI-D. The difference in mortality is concerning though? Simultaneous pub 👇🏾 #kidneywk
jamanetwork.com/journals/jam...
jamanetwork.com/journals/jam...
Shocking first high impact trial of the day. Fish oil reduces CV events in dialysis patients! #Pisces #kidneywk
Simultaneous pub in NEJM
www.nejm.org/doi/full/10....
Simultaneous pub in NEJM
www.nejm.org/doi/full/10....
November 7, 2025 at 4:45 PM
Shocking first high impact trial of the day. Fish oil reduces CV events in dialysis patients! #Pisces #kidneywk
Simultaneous pub in NEJM
www.nejm.org/doi/full/10....
Simultaneous pub in NEJM
www.nejm.org/doi/full/10....
@sophia-kidney.bsky.social is working really hard at this conference #kidneywk
November 6, 2025 at 7:37 PM
@sophia-kidney.bsky.social is working really hard at this conference #kidneywk
@sophia-kidney.bsky.social got shoved into a corner by ASN but well
worth the trek to check out her poster and try out abcKidney #kidneywk
worth the trek to check out her poster and try out abcKidney #kidneywk
November 6, 2025 at 4:58 PM
@sophia-kidney.bsky.social got shoved into a corner by ASN but well
worth the trek to check out her poster and try out abcKidney #kidneywk
worth the trek to check out her poster and try out abcKidney #kidneywk
Small trial of lysine chloride in euvolemic patients with heart failure. Median furosemide dose was 80mg. Chloride supplementation reduced plasma volume and improved diuretic response. Interesting but maybe not the population I would use it in? #kidneywk
November 6, 2025 at 4:07 PM
Small trial of lysine chloride in euvolemic patients with heart failure. Median furosemide dose was 80mg. Chloride supplementation reduced plasma volume and improved diuretic response. Interesting but maybe not the population I would use it in? #kidneywk
We have a new therapy for type 1 diabetes! FINE-ONE with significant proteinuria reduction compared to placebo on a background of RASi with an acceptable safety profile. Where’s the simultaneous pub?? Sglt2 inhibitors are next…#kidneywk
November 6, 2025 at 3:26 PM
We have a new therapy for type 1 diabetes! FINE-ONE with significant proteinuria reduction compared to placebo on a background of RASi with an acceptable safety profile. Where’s the simultaneous pub?? Sglt2 inhibitors are next…#kidneywk
Interim analysis of atacicept (dual BAFF/APRIL inhibitor) shows successful proteinuria reduction vs placebo. Also reduced Gd-IgA1 levels. Adding to the IgA armamentarium. Simultaneous pub 👇🏾 #kidneywk
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
November 6, 2025 at 3:21 PM
Interim analysis of atacicept (dual BAFF/APRIL inhibitor) shows successful proteinuria reduction vs placebo. Also reduced Gd-IgA1 levels. Adding to the IgA armamentarium. Simultaneous pub 👇🏾 #kidneywk
www.nejm.org/doi/full/10....
www.nejm.org/doi/full/10....
Interesting study in pts w/T1D w/ or w/out flozins and comp. With healthy controls. Less glomerulomegaly on routine biopsies. Flozins impacted metabolic transcripts throughout the nephron - ie the effect wasn’t isolated to the proximal tubule. Showing they are powerful metabolic drugs. #nephsky
July 21, 2025 at 10:08 PM
Interesting study in pts w/T1D w/ or w/out flozins and comp. With healthy controls. Less glomerulomegaly on routine biopsies. Flozins impacted metabolic transcripts throughout the nephron - ie the effect wasn’t isolated to the proximal tubule. Showing they are powerful metabolic drugs. #nephsky
If you're applying to a Nephrology fellowship, let @glaucomflecken.bsky.social tell you why you need to come to @pdxkidney.bsky.social. Then let us tell you what makes it such a great and unique training program! #nephsky
July 17, 2025 at 4:41 PM
If you're applying to a Nephrology fellowship, let @glaucomflecken.bsky.social tell you why you need to come to @pdxkidney.bsky.social. Then let us tell you what makes it such a great and unique training program! #nephsky
Huge thanks to @hswapnil.medsky.social for the invite and to everyone in Ottawa for the incredible hospitality, I had a great time!
As a bonus I got to check out the tulip festival (pics courtesy of swap)
As a bonus I got to check out the tulip festival (pics courtesy of swap)
May 16, 2025 at 2:28 PM
Huge thanks to @hswapnil.medsky.social for the invite and to everyone in Ottawa for the incredible hospitality, I had a great time!
As a bonus I got to check out the tulip festival (pics courtesy of swap)
As a bonus I got to check out the tulip festival (pics courtesy of swap)
Really fascinating talk this morning by Dr. Hiroyuki Nakai regarding AAV vector-mediated gene therapy for Alports disease @pdxkidney.bsky.social
April 18, 2025 at 3:40 PM
Really fascinating talk this morning by Dr. Hiroyuki Nakai regarding AAV vector-mediated gene therapy for Alports disease @pdxkidney.bsky.social
Often consulted after initial correction attempts in hyponatremia.👇called after a 12 mmol/L correction over 8 hrs (primary polydipsia). Previously I would've relowered the Na but with the new data (whether you agree or not) we decided to keep things stable until 24h mark. What would you do? #nephsky
April 8, 2025 at 5:08 PM
Often consulted after initial correction attempts in hyponatremia.👇called after a 12 mmol/L correction over 8 hrs (primary polydipsia). Previously I would've relowered the Na but with the new data (whether you agree or not) we decided to keep things stable until 24h mark. What would you do? #nephsky
Giving a talk about heart failure treatment in patients with CKD. 👇 the protocol for our clinic
February 28, 2025 at 4:38 PM
Giving a talk about heart failure treatment in patients with CKD. 👇 the protocol for our clinic
That’s the difference between Michigan and Portland. A snowy day here means you don’t go to the hospital.
February 13, 2025 at 5:33 PM
That’s the difference between Michigan and Portland. A snowy day here means you don’t go to the hospital.
Co-management is so important. When you leave it all up to Cardiologists, patients with an elevated creatinine get undertreated and probably vice-versa 👇
December 19, 2024 at 5:57 PM
Co-management is so important. When you leave it all up to Cardiologists, patients with an elevated creatinine get undertreated and probably vice-versa 👇
Well this should add fuel to the fluid wars...
December 19, 2024 at 5:25 AM
Well this should add fuel to the fluid wars...
"Retro" is usually reserved for fashion and music. Typically not something you see in medicine - unless it's acetazolamide I guess.
December 12, 2024 at 5:53 PM
"Retro" is usually reserved for fashion and music. Typically not something you see in medicine - unless it's acetazolamide I guess.
Given our concern for obstruction we called IR for percutaneous nephrostomy tubes, which they felt were not indicated on the basis of only mild radiographic changes and requested a CT urogram, which showed an atrophic L kidney and 3 stones in the distal R ureter with "trace hydrouteronephrosis"
December 9, 2024 at 10:53 PM
Given our concern for obstruction we called IR for percutaneous nephrostomy tubes, which they felt were not indicated on the basis of only mild radiographic changes and requested a CT urogram, which showed an atrophic L kidney and 3 stones in the distal R ureter with "trace hydrouteronephrosis"
The complete anuria was odd to us as typically patients with acute tubular injury are oliguric rather than anuric (except for severe cases). We had a high suspicion for obstruction so requested an US. R kidney shown here (the L kidney was difficult to visualize). Read was that of "mild hydro"
December 9, 2024 at 10:53 PM
The complete anuria was odd to us as typically patients with acute tubular injury are oliguric rather than anuric (except for severe cases). We had a high suspicion for obstruction so requested an US. R kidney shown here (the L kidney was difficult to visualize). Read was that of "mild hydro"
December 6, 2024 at 8:24 PM