Ane Appelt
banner
cancerphysicist.bsky.social
Ane Appelt
@cancerphysicist.bsky.social
Physicist, cancer & radiotherapy researcher, trialist, data nerd. Global low-carbon / train traveller. Occasional caver & underground photographer. Professor of Clinical Medical Physics at Rigshospitalet & DTU, Copenhagen, DK #radonc #medphys
AAPM, here I come! Only my 2nd time ever, and 7 years since I last went 😳 Have acquired a few more grey hair & wrinkles in the meantime, but still excited to hear what’s happening on the other side of the pond. And please all reach out if you want to meet up! #medphys #AAPM2025
July 25, 2025 at 3:07 PM
Biked the 7km home in the rain in high heels and a dress. I believe this means I’m now formally reassimilated? 🇩🇰 🚴‍♀️
#Copenhagen #CyclingCulture
July 11, 2025 at 7:00 PM
My inaugural lecture as Professor of Clinical Medical Physics at Rigshospitalet and DTU will be on the 6th Oct at 3pm in Auditorium 1, Rigshospitalet, Copenhagen

It would be lovely to see a lot of familiar faces, for the lecture and for the reception afterwards ☺️
#medphys #radonc
July 2, 2025 at 8:04 AM
Survived the first week in my new workplace. Got an office, computer, keys & ID card - and so many lovely and welcoming colleagues. Key items have been added to my empty office shelves, and I’ve got tentative plans for stuff to work on over the coming months. Could do with some sleep, though 😂
June 20, 2025 at 4:16 PM
Oh well, that didn’t quite go to plan … Got 9 hours of restful sleep and a shower, but now stuck in Cologne waiting for a replacement bus. At least I’ve got good company! #ESTRO25
May 7, 2025 at 6:59 AM
My feet are shattered by too much walking in heels, and I'm functioning on about 15 hours of sleep over the last five days. So now hanging out in a cool little cafe, trying to keep awake before boarding the night train to Brussels🚆
See you all in Stockholm next year #ESTRO25
May 6, 2025 at 4:30 PM
I gave a total of 5 talks, attended & chaired numerous meetings, made it to too few of the scientific talks (🙏 online recordings!), and saw so many friends and colleagues that I have lost count a long time ago. I even managed to meet a few new people (@NiuSanford!) #ESTRO25
May 6, 2025 at 4:30 PM
I got to catch up with my partner in crime (i.e. all things #reirradiation) Eliana Vasquez Osorio, who gave a brilliant - as always - talk on image registration for reRT dose accumulation today #radonc #medphys #ESTRO25
May 6, 2025 at 4:30 PM
What a blast - #ESTRO25 has been absolutely amazing 🙌
The scientific programme was outstanding: not only the clinical track - with many, many large trials reported - but also extremely strong #medphys, #RTT and #radbio tracks
May 6, 2025 at 4:30 PM
Love it when a plan comes together! This year’s joint #ESTRO25-AAPM symposium is the culmination of 3 years of cross-Atlantic #reirradiation collaboration🤩
🔹Chuck Mayo: #medphys-led workflows
🔹Søren Bentzen: #radbio
🔹Marija Popovic: dose accumulation
🔹Lone Hoffmann: reRT trial design & QA
May 6, 2025 at 7:37 AM
Dose metrics linked to bowel toxicity for rectal RT in the RAPIDO trial: Amazing work by Max Tanaka from NKI

Medium-to-high dose volumes for bowel bag (RTOG or Embrace) best predictors for both acute & late toxicity - V30Gy for LCRT, V20Gy for short course #ESTRO25 #radonc #medphys
May 5, 2025 at 3:59 PM
Hella Sand looked at rigid v deformable reg for lung #reirradiation. Both performed well, with good inter-centre consistency, but less variation for DIR, especially for cumulative max dose. Results have driven recommendations in the CURE Lung reRT trial #radonc #medphys #ESTRO25
May 5, 2025 at 3:41 PM
Isak Wahlsted led a national study of dose accumulation for #reirradiation: 8 diverse cases evaluated in all Danish RT centres

Image reg was consistent & high quality; but differences in a/b & tissue recovery gave substantial intercentre variation in cumulative dose #medphys #radonc #ESTRO25
May 5, 2025 at 3:41 PM
Great to see first outputs from ESTRO-EORTC ReCare cohort on high-dose #reirradiation - such data are sorely needed! Jonas Willmann presented characteristics for first 290 patients #ESTRO25; w/ large groups of thoracic & pelvic cancers. Current patient enrolment closing in on 500 patients! #radonc
May 5, 2025 at 8:40 AM
What a way to celebrate a paper! Arnaud Beddok had arranged for chocolate and champagne for the whole co-author group to mark the acceptance of a large review paper for publication. Way to set the bar high for future papers 😅 #ESTRO25 #radonc #medphys
May 5, 2025 at 8:02 AM
Loads of interesting #irradiation sessions today as well at #ESTRO25!
#radonc #medphys
May 5, 2025 at 7:04 AM
Amazing Reirradiation Meet&Greet session at #ESTRO25 today! Fantastic turnout, and great opportunity to present how much we’ve already done on #reirradiation within ESTRO

Now really looking forward to working with all the new members of the Reirradiation Focus group #radonc #medphys
May 4, 2025 at 2:21 PM
Well, I’ve managed one coffee … @bostonscientific.bsky.social has almost no queue, and good (and surprisingly strong!) coffee ☕️ #ESTRO25 #coffeechallenge
May 4, 2025 at 2:03 PM
Slightly delayed, but a summary of the key reirradiation sessions and presentation at today's #ESTRO25

In particular, note the dedicated #RTT and #brachytherapy reirradiation sessions 😍

#radonc #medphys #reirradiation
May 4, 2025 at 10:05 AM
I’m SO delighted to finally see first STAR-TREC data reported 🤩 #ESTRO25

Short course RT vs chemorad for organ preservation in early stage rectal cancer

61% vs 80% TME-free survival at 12 months ➡️ More organ preservation with long-course chemorad!
#radonc #rectalcancer
May 4, 2025 at 10:02 AM
Excellent to also see the quality of life data, demonstrating the positive patient impact of RT dose reduction
#radonc #ESTRO25
May 4, 2025 at 9:53 AM
PLATO ACT 4 results for dose de-escalation in early-stage anal cancer are out! Prof Sebag-Montefiore presents on the plenary stage at #ESTRO24

3-year locoregional failure 16.4% for standard dose IMRT vs 12.4% reduced dose IMRT

Primary endpoint is met! Reduced dose IMRT is safe & effective
#radonc
May 4, 2025 at 9:50 AM
Yesterday was terrible for my coffee sampling! Far too busy meeting people, and only managed a single coffee from the GE stand. At least it was a delightful reunion with both their barista and their excellent coffee (and the queue was short!). #ESTRO25 #CoffeeChallenge
May 4, 2025 at 5:58 AM
Things that make me happy:
Seeing an RT planning & evaluation solution for #reirradiation that I’ve helped develop in its (nearly) final version. Amazing work by @raysearchlabs.bsky.social @solstina.bsky.social @crukradnetleeds.bsky.social & colleagues.
Probably highlight of #ESTRO25 so far for me 😍
May 3, 2025 at 2:05 PM
Why? Not quite clear, but Prof Offersen speculates that the effective dose might simply be too low with 40Gy/15# for this group.
(They’ve carefully confirmed that it’s not a question of RT quality!)
#ESTRO25 #radonc #medphys
May 3, 2025 at 9:05 AM