CKD-EPI, MDRD etc give us GFR corrected for body surface area (ml/min/1.73m2)
BUT we're supposed to use the *absolute* GFR (ml/min) for drug dosing (eg KDIGO 2024 guidelines below; FDA agrees)
in obesity, the computer's ml/min/1.73m2 can be way too low #EMIMCC
CKD-EPI, MDRD etc give us GFR corrected for body surface area (ml/min/1.73m2)
BUT we're supposed to use the *absolute* GFR (ml/min) for drug dosing (eg KDIGO 2024 guidelines below; FDA agrees)
in obesity, the computer's ml/min/1.73m2 can be way too low #EMIMCC
Metronidazole 500mg q12h dosing was not associated with worse outcomes compared to metronidazole 500mgq8h
Metro:500mgq12h must be used for most types of infections #idsky #medsky #EMIMCC
www.sciencedirect.com/science/arti...
Metronidazole 500mg q12h dosing was not associated with worse outcomes compared to metronidazole 500mgq8h
Metro:500mgq12h must be used for most types of infections #idsky #medsky #EMIMCC
www.sciencedirect.com/science/arti...
Pessimist: The cup is half empty
ID Doc (when a new antibiotic gets approved): The cup is both
#IDSky
Pessimist: The cup is half empty
Anesthesiologist: Did you just drink half that cup? Now you’re not NPO
Pessimist: The cup is half empty
ID Doc (when a new antibiotic gets approved): The cup is both
#IDSky