@jclinical-invest.bsky.social

This has been a great team effort, big thanks to everyone involved! @mskcancercenter.bsky.social

When we compared the MAFs between sample types in CH we didn't see a significant difference however comparing these in AML and MDS we did see a difference in MDS with cfDNA from plasma being much higher than buffy coat. We hypothesize this is coming from the bone marrow but did not follow this up.

We were able to detect mutations across sample types (buffy coat DNA and saliva and blood plasma cfDNA) reliably down to 0.05%-0.1% MAF while using a single sample the limit of detection was 0.3% MAF when sequenced at high depth.

Work done in Luis Diaz's lab at @mskcancercenter.bsky.social

Climate change crafting night but I’d definitely be interested in learning more about Bad art for good if I saw it advertised.

Thank you!

Yes very glad to see that!

Update: apparently she declined compensation!