Professor Lesley Hoyles
@bugsinyourguts.bsky.social
And all this science I don't understand, it's just my job five days a week.
Professor of Microbiome and Systems Biology @ Nottingham Trent University. 🏳️🌈
Working predominantly on the human gut microbiota.
All views my own.
Professor of Microbiome and Systems Biology @ Nottingham Trent University. 🏳️🌈
Working predominantly on the human gut microbiota.
All views my own.
Over 17,000 submissions for this year's MSCA Postdoctoral Fellowships, and it's really no surprise where most applicants are applying from.
September 11, 2025 at 10:44 PM
Over 17,000 submissions for this year's MSCA Postdoctoral Fellowships, and it's really no surprise where most applicants are applying from.
Microbiome Innovation One Health Conference 2025.
15-16 September 2025, University of Oxford.
#microbiomesky
15-16 September 2025, University of Oxford.
#microbiomesky
August 4, 2025 at 2:04 PM
Microbiome Innovation One Health Conference 2025.
15-16 September 2025, University of Oxford.
#microbiomesky
15-16 September 2025, University of Oxford.
#microbiomesky
Great to have the opportunity to present our work on CAUTI-associated bacteria at #HISCON. Good to get feedback from clinicians on the work.
June 18, 2025 at 1:00 PM
Great to have the opportunity to present our work on CAUTI-associated bacteria at #HISCON. Good to get feedback from clinicians on the work.
The pinnacle of my scientific career.
June 12, 2025 at 9:12 PM
The pinnacle of my scientific career.
Interested in seeing whether your favourite bacterium is well represented in the AllTheBacteria database of 2,440,377 assembled (and annotated) genomes?
96 % of all genomes are high quality.
Species-level assemblies represented at >=0.1 % of the total dataset. #microsky
96 % of all genomes are high quality.
Species-level assemblies represented at >=0.1 % of the total dataset. #microsky
June 8, 2025 at 9:52 AM
Interested in seeing whether your favourite bacterium is well represented in the AllTheBacteria database of 2,440,377 assembled (and annotated) genomes?
96 % of all genomes are high quality.
Species-level assemblies represented at >=0.1 % of the total dataset. #microsky
96 % of all genomes are high quality.
Species-level assemblies represented at >=0.1 % of the total dataset. #microsky
The leupeptin BGC looks to be pretty much restricted to K. michiganensis. >90 % of all genomes encode the complete BGC. Our annotations mean that this BGC will be included in the next release of antiSMASH (unexpected bonus 😀).
(AllTheBacteria a huge help here - thanks @zaminiqbal.bsky.social!)
(AllTheBacteria a huge help here - thanks @zaminiqbal.bsky.social!)
April 24, 2025 at 7:58 PM
The leupeptin BGC looks to be pretty much restricted to K. michiganensis. >90 % of all genomes encode the complete BGC. Our annotations mean that this BGC will be included in the next release of antiSMASH (unexpected bonus 😀).
(AllTheBacteria a huge help here - thanks @zaminiqbal.bsky.social!)
(AllTheBacteria a huge help here - thanks @zaminiqbal.bsky.social!)
We've covered histamine, ethanol, colibactin, tilivalline, tilimycin, pyrazinones, pyrazines and N-acyl amides.
This is one area of research where much more is known about non-pneumoniae Klebsiella spp. than K. pneumoniae.
This is one area of research where much more is known about non-pneumoniae Klebsiella spp. than K. pneumoniae.
April 24, 2025 at 7:49 PM
We've covered histamine, ethanol, colibactin, tilivalline, tilimycin, pyrazinones, pyrazines and N-acyl amides.
This is one area of research where much more is known about non-pneumoniae Klebsiella spp. than K. pneumoniae.
This is one area of research where much more is known about non-pneumoniae Klebsiella spp. than K. pneumoniae.
This has made @drsimonmcarthur.bsky.social and I laugh this morning (but in a good - and very middle class - way). #gutbrainaxis #IShopAtWaitroseBecause
March 29, 2025 at 12:58 PM
This has made @drsimonmcarthur.bsky.social and I laugh this morning (but in a good - and very middle class - way). #gutbrainaxis #IShopAtWaitroseBecause
Ziyaad Dangor talking on Klebsiella pneumoniae as an important infectious cause of death in infants in LMIC settings.
K. pneumoniae contributes to "pathway to death" in almost a quarter of infants between months 1 and 59 months of life.
#KLEBS2024
K. pneumoniae contributes to "pathway to death" in almost a quarter of infants between months 1 and 59 months of life.
#KLEBS2024
November 20, 2024 at 5:28 PM
Ziyaad Dangor talking on Klebsiella pneumoniae as an important infectious cause of death in infants in LMIC settings.
K. pneumoniae contributes to "pathway to death" in almost a quarter of infants between months 1 and 59 months of life.
#KLEBS2024
K. pneumoniae contributes to "pathway to death" in almost a quarter of infants between months 1 and 59 months of life.
#KLEBS2024
With a bit of curation* sandpiper (sandpiper.qut.edu.au/About) data is useful for summarizing species prevalence across different metagenomic datasets.
(*Figure my own after wrangling with the myriad source descriptors provided under the heading 'organism'.)
(*Figure my own after wrangling with the myriad source descriptors provided under the heading 'organism'.)
November 15, 2024 at 12:18 PM
With a bit of curation* sandpiper (sandpiper.qut.edu.au/About) data is useful for summarizing species prevalence across different metagenomic datasets.
(*Figure my own after wrangling with the myriad source descriptors provided under the heading 'organism'.)
(*Figure my own after wrangling with the myriad source descriptors provided under the heading 'organism'.)
Any excuse for a video of my favourite bird.
November 8, 2024 at 5:33 PM
Any excuse for a video of my favourite bird.
Presented, this morning at the Scottish Microbiology Association autumn meeting, on our work on non-pneumoniae Klebsiella spp. in clinical and veterinary settings.
Very happy with the Klebsiella bowl I was given by my hosts!
Very happy with the Klebsiella bowl I was given by my hosts!
November 2, 2024 at 9:55 AM
Presented, this morning at the Scottish Microbiology Association autumn meeting, on our work on non-pneumoniae Klebsiella spp. in clinical and veterinary settings.
Very happy with the Klebsiella bowl I was given by my hosts!
Very happy with the Klebsiella bowl I was given by my hosts!
Long may the downward trend regarding gut-brain axis reviews continue.
June 12, 2024 at 11:38 AM
Long may the downward trend regarding gut-brain axis reviews continue.
Not able to attend #MicroSoc24, but my team is being represented by Sam Dawson and Mohamed Eladawy.
Today, check out Mohamed's poster (no. 181) on the first detailed genomic analyses of uropathogens in an Egyptian clinical setting, and the importance of comparing genotypic and phenotypic AMR data.
Today, check out Mohamed's poster (no. 181) on the first detailed genomic analyses of uropathogens in an Egyptian clinical setting, and the importance of comparing genotypic and phenotypic AMR data.
April 9, 2024 at 2:04 PM
Not able to attend #MicroSoc24, but my team is being represented by Sam Dawson and Mohamed Eladawy.
Today, check out Mohamed's poster (no. 181) on the first detailed genomic analyses of uropathogens in an Egyptian clinical setting, and the importance of comparing genotypic and phenotypic AMR data.
Today, check out Mohamed's poster (no. 181) on the first detailed genomic analyses of uropathogens in an Egyptian clinical setting, and the importance of comparing genotypic and phenotypic AMR data.
I know what that pathway is missing...
February 15, 2024 at 5:46 PM
I know what that pathway is missing...
Post a meme made by you
December 19, 2023 at 12:01 PM
Post a meme made by you
Importance of Mohamed's study in an Egyptian clinical context.
October 30, 2023 at 12:27 PM
Importance of Mohamed's study in an Egyptian clinical context.
Reading a clinical FMT paper where the only screening criterion for donors was pretty much "yep, jobby's a good 'un".
October 1, 2023 at 7:38 PM
Reading a clinical FMT paper where the only screening criterion for donors was pretty much "yep, jobby's a good 'un".
Share your #thesis quotes! #academia
My dogs were also thanked for keeping me sane.
My dogs were also thanked for keeping me sane.
September 19, 2023 at 1:46 PM
Share your #thesis quotes! #academia
My dogs were also thanked for keeping me sane.
My dogs were also thanked for keeping me sane.
TFW you've done a comprehensive genome-based analysis and a reviewer wants a 16S rRNA gene-based tree for the same strains.
September 1, 2023 at 12:54 PM
TFW you've done a comprehensive genome-based analysis and a reviewer wants a 16S rRNA gene-based tree for the same strains.
Latest purchase, which will never be seen in public.
August 12, 2023 at 5:24 PM
Latest purchase, which will never be seen in public.
TFW you're trying to find guidance on getting ethics and questions together for interviewing patients and all the people who could help you are on holiday until September.
August 5, 2023 at 1:18 PM
TFW you're trying to find guidance on getting ethics and questions together for interviewing patients and all the people who could help you are on holiday until September.
Excellent opportunity for anyone wanting to undertake a postdoc in phage research, with Professor Andrey Shkoporov
@AShkoporov at UCC. Contact Andrey directly about this position.
@AShkoporov at UCC. Contact Andrey directly about this position.
July 30, 2023 at 12:47 PM
Excellent opportunity for anyone wanting to undertake a postdoc in phage research, with Professor Andrey Shkoporov
@AShkoporov at UCC. Contact Andrey directly about this position.
@AShkoporov at UCC. Contact Andrey directly about this position.
TFW you haven't looked at a dataset for a while, and now have to spend 2 days getting your head round exactly where things were when you had to turn your attention elsewhere.
July 27, 2023 at 10:19 AM
TFW you haven't looked at a dataset for a while, and now have to spend 2 days getting your head round exactly where things were when you had to turn your attention elsewhere.