Brinda Bala, PhD
brindabala.bsky.social
Brinda Bala, PhD
@brindabala.bsky.social
🎓Postdoc at @UoN_BDI @MedicineUoN | Precision Medicine | Cancer and Stem Cells | Organoids | Bioinformatics 🧬👩🏻‍💻 🔬👩🏻‍🔬 🇮🇳🇹🇭🇬🇧
Had the pleasure of attending the London Gastrointestinal Organoid Network (LION) at the Francis Crick Institute 🦁🧬 Grateful to be part of a community pushing the frontiers of organoid research! A fantastic day of science and gut instincts #LION #Organoids
July 22, 2025 at 11:18 AM
Reposted by Brinda Bala, PhD
March 22, 2025 at 7:52 AM
Reposted by Brinda Bala, PhD
Intestinal #organoid goes rogue and flips polarity 🤯
@vucellimaging.bsky.social
#epithelial #cellbiology #microscopy
December 11, 2024 at 11:47 PM
Reposted by Brinda Bala, PhD
December 3, 2024 at 9:04 PM
Reposted by Brinda Bala, PhD
#Organoid research starter pack.
I didn't find many researchers from the field yet, please comment/text me to be added!
go.bsky.app/RmXgs6d
November 24, 2024 at 8:32 AM
Reposted by Brinda Bala, PhD
Very proud of this one. Sarah Hamoudi, PhD student in the lab, developed autologous cocultures between mucosal T cells and epithelial organoids from control or from patients with Crohn's disease.
www.biorxiv.org/content/10.1...
T cell mediated impairment of epithelial integrity in Crohn's disease
T lymphocytes play a major role in intestinal homeostasis, with a particular impact on the balance between self-renewal and differentiation of intestinal epithelial cells (IECs). In Crohn's disease (C...
www.biorxiv.org
November 16, 2024 at 4:50 PM
In an age of info overload, are we well informed or just misinformed? It’s crucial for scientists to communicate their findings clearly and effectively to everyone, not just their peers. Scientific literacy will promote a society that values evidence over hearsay.
#StandingUpForScience Workshop
June 10, 2024 at 12:10 PM
Two studies report that upper crypt progenitor cells are responsible for #intestinal epithelial regeneration and restoration of homeostasis and not LGR5+ stem cells, particularly after injury.
1. www.cell.com/cell/fulltex...
2. www.cell.com/cell/fulltex...

#StemCells #Gut 🧫
Time-resolved fate mapping identifies the intestinal upper crypt zone as an origin of Lgr5+ crypt base columnar cells
A revised model of the cellular hierarchy during intestinal epithelial regeneration is presented, with the identification of multi-potent intestinal stem cells in the upper crypt zone. These cells are...
www.cell.com
June 10, 2024 at 12:07 PM