Briggs Group
@briggsgroup.bsky.social
Briggs group at MPI Biochemistry
Department of Cell and Virus Structure
Cryo-EM, tomography, CLEM, coated vesicles, enveloped viruses.
Department of Cell and Virus Structure
Cryo-EM, tomography, CLEM, coated vesicles, enveloped viruses.
Without SP2, HIV-1 fuses more slowly with target cells. We worked with Kräusslich and Müller labs @uniheidelberg.bsky.social,
@wmothes.bsky.social at @yalemicropath.bsky.social, Robert Dick @emorydeptofmed.bsky.social and Kun Qu.
Read the full paper @nature.com here: www.nature.com/articles/s41...
@wmothes.bsky.social at @yalemicropath.bsky.social, Robert Dick @emorydeptofmed.bsky.social and Kun Qu.
Read the full paper @nature.com here: www.nature.com/articles/s41...
The conserved HIV-1 spacer peptide 2 triggers matrix lattice maturation - Nature
A study reports that the structural maturation of the matrix domain of the Gag protein of HIV-1 is induced by the proteolytic release and binding of the spacer peptide SP2.
www.nature.com
February 28, 2025 at 2:04 PM
Without SP2, HIV-1 fuses more slowly with target cells. We worked with Kräusslich and Müller labs @uniheidelberg.bsky.social,
@wmothes.bsky.social at @yalemicropath.bsky.social, Robert Dick @emorydeptofmed.bsky.social and Kun Qu.
Read the full paper @nature.com here: www.nature.com/articles/s41...
@wmothes.bsky.social at @yalemicropath.bsky.social, Robert Dick @emorydeptofmed.bsky.social and Kun Qu.
Read the full paper @nature.com here: www.nature.com/articles/s41...
James Stacey and @dhrebik.bsky.social generated high-resolution structures of matrix within virus particles by #cryoEM, finding SP2 bound to a pocket on matrix (we previously thought the ligand was a lipid):
February 28, 2025 at 2:04 PM
James Stacey and @dhrebik.bsky.social generated high-resolution structures of matrix within virus particles by #cryoEM, finding SP2 bound to a pocket on matrix (we previously thought the ligand was a lipid):