@brangwynnelab.bsky.social
A tremendous honor! Thrilled & humbled to receive 2025 Keio Medical Science Prize for launching LLPS #phaseseparation field (= #softmatter + #cellbio) w collaborators esp @HymanLab. & Congrats to Akiko Iwasaki @virusesimmunity.bsky.social. www.princeton.edu/news/2025/09...
#KeioMedicalSciencePrize
#KeioMedicalSciencePrize
Bioengineer Clifford Brangwynne wins Keio Medical Science Prize
Japan’s Keio University awards the prize annually to honor contributions in medicine and life sciences. Brangwynne is being recognized for groundbreaking work that has opened up a new field of cell bi...
www.princeton.edu
September 20, 2025 at 6:16 PM
A tremendous honor! Thrilled & humbled to receive 2025 Keio Medical Science Prize for launching LLPS #phaseseparation field (= #softmatter + #cellbio) w collaborators esp @HymanLab. & Congrats to Akiko Iwasaki @virusesimmunity.bsky.social. www.princeton.edu/news/2025/09...
#KeioMedicalSciencePrize
#KeioMedicalSciencePrize
Reposted
🎉 Congratulations to HHMI Investigators Clifford Brangwynne and Akiko Iwasaki, the two winners of the 30th annual Keio Medical Science Prize. This international prize, awarded by Keio University in Tokyo, honors scientists who have made major contributions to the fields of medical or life sciences.
September 19, 2025 at 12:56 PM
🎉 Congratulations to HHMI Investigators Clifford Brangwynne and Akiko Iwasaki, the two winners of the 30th annual Keio Medical Science Prize. This international prize, awarded by Keio University in Tokyo, honors scientists who have made major contributions to the fields of medical or life sciences.
these people in my lab are amazing
September 20, 2025 at 12:16 AM
these people in my lab are amazing
Awesome work Anita, congrats on an amazing paper!
Cells organize key processes in biomolecular condensates, such as the multiphase nucleolus where ribosomes are made 🏭. Due to its dynamic and compartmentalized nature, small molecule perturbations of this process💊 lead to fast and distinct morphology rearrangements🌀. (2/10)
August 20, 2025 at 8:25 PM
Awesome work Anita, congrats on an amazing paper!
Check out this awesome story about the work of an awesome (former) undergrad in our lab @hollycheng.bsky.social who worked closely w @zs-biophys.bsky.social Howard Stone, James Roggeveen & Huan Wang. bioengineering.princeton.edu/news/2025/st...
Starting as an undergraduate project, an experiment reveals cells’ secrets
Holly Cheng and her colleagues were the first to successfully use micropipette aspiration to measure parts from a living cell while they were still biologically active
bioengineering.princeton.edu
August 19, 2025 at 3:17 PM
Check out this awesome story about the work of an awesome (former) undergrad in our lab @hollycheng.bsky.social who worked closely w @zs-biophys.bsky.social Howard Stone, James Roggeveen & Huan Wang. bioengineering.princeton.edu/news/2025/st...
Congrats @yoonjikim.bsky.social and co-authors!!!!!
Our squid primary cell isolation protocol is now out in
@cp-starprotocols.bsky.social⭐️🦑🧫This protocol enables molecular studies of cephalopod biology, aging, and basic cell physiology. Thanks to @brangwynnelab.bsky.social Hailey Tanner and Josh Rosenthal! Check it out here tinyurl.com/3knvkhyh 🤩
@cp-starprotocols.bsky.social⭐️🦑🧫This protocol enables molecular studies of cephalopod biology, aging, and basic cell physiology. Thanks to @brangwynnelab.bsky.social Hailey Tanner and Josh Rosenthal! Check it out here tinyurl.com/3knvkhyh 🤩
August 19, 2025 at 3:13 PM
Congrats @yoonjikim.bsky.social and co-authors!!!!!
Reposted
It has been a dream come true to lead a rotation in the @mblscience.bsky.social Physiology course - thanks to the amazing Directors @gladfelterlab.bsky.social and @brangwynnelab.bsky.social, course staff, TAs, and students!
July 12, 2025 at 11:43 PM
It has been a dream come true to lead a rotation in the @mblscience.bsky.social Physiology course - thanks to the amazing Directors @gladfelterlab.bsky.social and @brangwynnelab.bsky.social, course staff, TAs, and students!
Reposted
Combining sequencing and imaging, @brangwynnelab.bsky.social maps the spatiotemporal dynamics of rRNA processing, demonstrating how rRNA serves as both a scaffold and a substrate for the nucleolus—a multiphase, liquid-like structure. 🧪 🧬
Mapping and engineering RNA-driven architecture of the multiphase nucleolus - Nature
Spatially segregated rRNA processing dictates nucleolar morphology and drives outward progression of pre-ribosomal RNA through nucleolar phases.
www.nature.com
July 14, 2025 at 2:06 PM
Combining sequencing and imaging, @brangwynnelab.bsky.social maps the spatiotemporal dynamics of rRNA processing, demonstrating how rRNA serves as both a scaffold and a substrate for the nucleolus—a multiphase, liquid-like structure. 🧪 🧬
Congrats to Jing @jesszhiyuezhao.bsky.social
& @dnamystrom.bsky.social on cool manuscript!!! Reveals how cell nucleus is a heterogeneous material, w chromatin organization controlling formation & phase behavior of nuclear condensates. #CellBiology #Chromatin #PhaseSeparation rdcu.be/evWxR
& @dnamystrom.bsky.social on cool manuscript!!! Reveals how cell nucleus is a heterogeneous material, w chromatin organization controlling formation & phase behavior of nuclear condensates. #CellBiology #Chromatin #PhaseSeparation rdcu.be/evWxR
Chromatin heterogeneity modulates nuclear condensate dynamics and phase behavior
Nature Communications - Chromatin heterogeneity in the cell nucleus modulates the size, mobility, and formation of biomolecular condensates; decreasing chromatin heterogeneity correlates with...
rdcu.be
July 12, 2025 at 8:33 PM
Congrats to Jing @jesszhiyuezhao.bsky.social
& @dnamystrom.bsky.social on cool manuscript!!! Reveals how cell nucleus is a heterogeneous material, w chromatin organization controlling formation & phase behavior of nuclear condensates. #CellBiology #Chromatin #PhaseSeparation rdcu.be/evWxR
& @dnamystrom.bsky.social on cool manuscript!!! Reveals how cell nucleus is a heterogeneous material, w chromatin organization controlling formation & phase behavior of nuclear condensates. #CellBiology #Chromatin #PhaseSeparation rdcu.be/evWxR
An amazing group of students this year in Brangwynne rotation @mblscience.bsky.social Physiology course!!!!
June 30, 2025 at 6:38 PM
An amazing group of students this year in Brangwynne rotation @mblscience.bsky.social Physiology course!!!!
Reposted
How to spy on condensates: technology feature in
@natmethods.nature.com
Our views on the topic, by Hyman,Rosen,Brangwynne, Sabari, Kappel,Xu & myself, presented here
@hymanlab.bsky.social @brangwynnelab.bsky.social @bsabari.bsky.social @kallikappel.bsky.social
www.nature.com/articles/s41...
@natmethods.nature.com
Our views on the topic, by Hyman,Rosen,Brangwynne, Sabari, Kappel,Xu & myself, presented here
@hymanlab.bsky.social @brangwynnelab.bsky.social @bsabari.bsky.social @kallikappel.bsky.social
www.nature.com/articles/s41...
How to spy on condensates - Nature Methods
Scientists track how these membraneless biomolecular foci self-organize for their cellular tasks.
www.nature.com
June 27, 2025 at 5:30 PM
How to spy on condensates: technology feature in
@natmethods.nature.com
Our views on the topic, by Hyman,Rosen,Brangwynne, Sabari, Kappel,Xu & myself, presented here
@hymanlab.bsky.social @brangwynnelab.bsky.social @bsabari.bsky.social @kallikappel.bsky.social
www.nature.com/articles/s41...
@natmethods.nature.com
Our views on the topic, by Hyman,Rosen,Brangwynne, Sabari, Kappel,Xu & myself, presented here
@hymanlab.bsky.social @brangwynnelab.bsky.social @bsabari.bsky.social @kallikappel.bsky.social
www.nature.com/articles/s41...
Reposted
How to spy on condensates: technology feature in @natmethods.nature.com on self-organization and collective properties of condensates with quotes from Anthony Hyman @hymanlab.bsky.social @mpi-cbg.de, @brangwynnelab.bsky.social, and many more. www.nature.com/articles/s41...
How to spy on condensates - Nature Methods
Scientists track how these membraneless biomolecular foci self-organize for their cellular tasks.
www.nature.com
June 25, 2025 at 7:50 AM
How to spy on condensates: technology feature in @natmethods.nature.com on self-organization and collective properties of condensates with quotes from Anthony Hyman @hymanlab.bsky.social @mpi-cbg.de, @brangwynnelab.bsky.social, and many more. www.nature.com/articles/s41...
Nice article about the latest in the biomolecular condensate field, with some nice images and quotes from us. www.nature.com/articles/s41...
How to spy on condensates - Nature Methods
Scientists track how these membraneless biomolecular foci self-organize for their cellular tasks.
www.nature.com
June 25, 2025 at 3:25 AM
Nice article about the latest in the biomolecular condensate field, with some nice images and quotes from us. www.nature.com/articles/s41...
The one and only Manu @prakashlab.bsky.social
inspiring @mblscience.bsky.social Physiology students at this morning's lecture.
inspiring @mblscience.bsky.social Physiology students at this morning's lecture.
June 18, 2025 at 3:58 PM
The one and only Manu @prakashlab.bsky.social
inspiring @mblscience.bsky.social Physiology students at this morning's lecture.
inspiring @mblscience.bsky.social Physiology students at this morning's lecture.
A great morning with the @mblscience.bsky.social
Physiology students after my talk today.
Physiology students after my talk today.
June 17, 2025 at 5:36 PM
A great morning with the @mblscience.bsky.social
Physiology students after my talk today.
Physiology students after my talk today.
Awesome paper alert! Learn about spectrum of chromatin condensate morphologies due to elastocapillary effects (no, liquids do not need to be spherical!), from amazing duo @dnamystrom.bsky.social & Hongbo Zhao, w/ important contributions from co-authors Jorine Eeftens, Mikko Haataja, Andrej Kosmrlj.
If heterochromatin is really a liquid-like condensate, why is it not spherical?
We investigated whether mechanical interactions between a condensate and a fiber network can explain the variety of morphologies seen in phase-separated nuclear compartments
www.biorxiv.org/content/10.1...
We investigated whether mechanical interactions between a condensate and a fiber network can explain the variety of morphologies seen in phase-separated nuclear compartments
www.biorxiv.org/content/10.1...
June 16, 2025 at 7:32 PM
Awesome paper alert! Learn about spectrum of chromatin condensate morphologies due to elastocapillary effects (no, liquids do not need to be spherical!), from amazing duo @dnamystrom.bsky.social & Hongbo Zhao, w/ important contributions from co-authors Jorine Eeftens, Mikko Haataja, Andrej Kosmrlj.
Princeton's new Omenn-Darling Bioengineering Institute is hiring! New building opening this Fall, & Princeton is an awesome place to live & do amazing research at intersection of engineering & life sciences. **Please spread the word*** bioengineering.princeton.edu/join/open.
June 11, 2025 at 6:30 PM
Princeton's new Omenn-Darling Bioengineering Institute is hiring! New building opening this Fall, & Princeton is an awesome place to live & do amazing research at intersection of engineering & life sciences. **Please spread the word*** bioengineering.princeton.edu/join/open.
Start of 2025 @mblscience.bsky.social Physiology course! This is the second year of Amy @gladfelterlab.bsky.social and I co-Directing this absolutely amazing and life-changing course: www.mbl.edu/education/ad...
June 9, 2025 at 3:03 PM
Start of 2025 @mblscience.bsky.social Physiology course! This is the second year of Amy @gladfelterlab.bsky.social and I co-Directing this absolutely amazing and life-changing course: www.mbl.edu/education/ad...
Such a wonderful symposium at UMichigan! And a fantastic opportunity to connect with our beloved benefactors (and Michiganders) Gil Omenn and Martha Darling, together with my Princeton/Omenn-Darling Bioengineering Institute colleague (& Deputy Director) @toettch.bsky.social
May 29, 2025 at 9:32 PM
Such a wonderful symposium at UMichigan! And a fantastic opportunity to connect with our beloved benefactors (and Michiganders) Gil Omenn and Martha Darling, together with my Princeton/Omenn-Darling Bioengineering Institute colleague (& Deputy Director) @toettch.bsky.social
Reposted
Very glad to contribute to this cool study of of nucleoli, led by former Princeton undergrad Holly Cheng!
P.S., we all looked much younger when we were working on this project (see picture below) 😁
P.S., we all looked much younger when we were working on this project (see picture below) 😁
May 28, 2025 at 9:10 PM
Very glad to contribute to this cool study of of nucleoli, led by former Princeton undergrad Holly Cheng!
P.S., we all looked much younger when we were working on this project (see picture below) 😁
P.S., we all looked much younger when we were working on this project (see picture below) 😁
Congrats to this year's Brangwynne lab new PhD Kevin Xu (co-advised with Avalos) and graduating undergrads Aya Abu-Alfa and Emmett Grover. Kevin is now CEO of a startup, Aya is off to MD/PhD program, and Emmett to medical school. Congratulations - we are so proud of you!!!!
May 28, 2025 at 7:34 PM
Congrats to this year's Brangwynne lab new PhD Kevin Xu (co-advised with Avalos) and graduating undergrads Aya Abu-Alfa and Emmett Grover. Kevin is now CEO of a startup, Aya is off to MD/PhD program, and Emmett to medical school. Congratulations - we are so proud of you!!!!
Nucleoli as biomolecular bubble tea! Congrats to former Princeton ugrad Holly Cheng (now GS @MIT) ->Holly's senior thesis work, a close collab w Roggeveen Wang & @zs-biophys.bsky.social &Stone. Come for the cool movies & stay for the viscoelasticity! www.pnas.org/doi/10.1073/pnas.2407423122
May 28, 2025 at 7:27 PM
Nucleoli as biomolecular bubble tea! Congrats to former Princeton ugrad Holly Cheng (now GS @MIT) ->Holly's senior thesis work, a close collab w Roggeveen Wang & @zs-biophys.bsky.social &Stone. Come for the cool movies & stay for the viscoelasticity! www.pnas.org/doi/10.1073/pnas.2407423122
Reposted
The 2025 Saltiel Life Sciences Symposium is this Thursday (5/29)!
@brangwynnelab.bsky.social will start us off with the Mary Sue and Kenneth Coleman Lecture at 9:00 AM, followed by talks from @jamesknunez.bsky.social at 9:55 and @leonardomorsut.bsky.social at 10:25.
myumi.ch/lsi-symposiu...
@brangwynnelab.bsky.social will start us off with the Mary Sue and Kenneth Coleman Lecture at 9:00 AM, followed by talks from @jamesknunez.bsky.social at 9:55 and @leonardomorsut.bsky.social at 10:25.
myumi.ch/lsi-symposiu...
May 27, 2025 at 3:18 PM
The 2025 Saltiel Life Sciences Symposium is this Thursday (5/29)!
@brangwynnelab.bsky.social will start us off with the Mary Sue and Kenneth Coleman Lecture at 9:00 AM, followed by talks from @jamesknunez.bsky.social at 9:55 and @leonardomorsut.bsky.social at 10:25.
myumi.ch/lsi-symposiu...
@brangwynnelab.bsky.social will start us off with the Mary Sue and Kenneth Coleman Lecture at 9:00 AM, followed by talks from @jamesknunez.bsky.social at 9:55 and @leonardomorsut.bsky.social at 10:25.
myumi.ch/lsi-symposiu...
So grateful for our amazing inaugural advisory council for the Omenn-Darling Bioengineering Institute, who came to Princeton last week to learn about and help guide all that is happening in ODBI, the future of Bioengineering at Princeton. Thank you all!!! bioengineering.princeton.edu
May 5, 2025 at 5:26 PM
So grateful for our amazing inaugural advisory council for the Omenn-Darling Bioengineering Institute, who came to Princeton last week to learn about and help guide all that is happening in ODBI, the future of Bioengineering at Princeton. Thank you all!!! bioengineering.princeton.edu
What drives cytoplasmic mRNA organization? We created unbiased, genome-wide maps of mesoscale RNA-RNA spatial proximity, revealing impact of encoded protein function. Fantastic work from @lindsayabecker.bsky.social @sofiquinodoz.bsky.social @davidaknowles.bsky.social www.biorxiv.org/content/10.1...
Genome-wide mapping of mesoscale neuronal RNA organization and condensation
Subcellular RNA organization can affect critical cellular functions. However, our understanding of RNA microenvironments, particularly biomolecular condensates, remains limited, largely due to a lack ...
www.biorxiv.org
April 21, 2025 at 1:48 PM
What drives cytoplasmic mRNA organization? We created unbiased, genome-wide maps of mesoscale RNA-RNA spatial proximity, revealing impact of encoded protein function. Fantastic work from @lindsayabecker.bsky.social @sofiquinodoz.bsky.social @davidaknowles.bsky.social www.biorxiv.org/content/10.1...