Stanford Brain Organogenesis Center
@brainorganogenesis.bsky.social
Creating, applying and broadly sharing human stem cell models of brain development and disease
Website: http://www.brainorganogenesis.org/
Website: http://www.brainorganogenesis.org/
A remarkable group!
An amazing group of scientists, philosophers, legal scholars, ethicists, policy makers, patient advocates, funders and trainees convened at Asilomar for one of the most stimulating meetings I have had the privilege to organize, focused on the ethics of research with neural #organoids & #assembloids
November 14, 2025 at 7:11 PM
A remarkable group!
Exciting event coming up! Please share broadly
By popular demand — the next edition of our hands-on @Stanford @BrOrganogenesis course is coming in 2026!
This year, the focus turns to neural #assembloids, reflecting the growing movement toward modeling circuit-level and complex cell-cell interactions in brain disease.
🧠 Deadline: mid-December
This year, the focus turns to neural #assembloids, reflecting the growing movement toward modeling circuit-level and complex cell-cell interactions in brain disease.
🧠 Deadline: mid-December
October 16, 2025 at 5:54 PM
Exciting event coming up! Please share broadly
All you ever wanted to know about #assembloids
Less than two weeks left to register for the inaugural conference on Assembloids & Complex Cell-Cell Interactions at @cshlnews.bsky.social
Check out the topics and amazing lineup of speakers!
Check out the topics and amazing lineup of speakers!
October 3, 2025 at 5:26 PM
All you ever wanted to know about #assembloids
Warmest congratulations from all of us here at Stanford and best wishes!
A bittersweet day as another postdoc leaves to start an independent lab at St Jude’s Children Hospital.
Xiaoyu Chen led fearless work on developing a therapeutic approach for Timothy syndrome—now advancing toward clinical trial.
Xiaoyu Chen led fearless work on developing a therapeutic approach for Timothy syndrome—now advancing toward clinical trial.
October 1, 2025 at 6:53 PM
Warmest congratulations from all of us here at Stanford and best wishes!
Reposted by Stanford Brain Organogenesis Center
One week left to register for the 1st conference on assembloids at @cshlnews.bsky.social this December. Spectacular list of speakers (see below) tackling cell-cell interactions across tissues and organs
Two amazing keynotes:
Ruslan M. Medzhitov & Joanna Wysocka
#assembloids #organoids
Two amazing keynotes:
Ruslan M. Medzhitov & Joanna Wysocka
#assembloids #organoids
September 12, 2025 at 6:28 PM
One week left to register for the 1st conference on assembloids at @cshlnews.bsky.social this December. Spectacular list of speakers (see below) tackling cell-cell interactions across tissues and organs
Two amazing keynotes:
Ruslan M. Medzhitov & Joanna Wysocka
#assembloids #organoids
Two amazing keynotes:
Ruslan M. Medzhitov & Joanna Wysocka
#assembloids #organoids
Reposted by Stanford Brain Organogenesis Center
Great news about our upcoming meeting at Asilomar on the Ethics of Neural #Organoids and #Assembloids Research!
We secured additional support to waive the registration fee for at least 30 participants, which is especially beneficial for trainees
If interested, complete the form at the link below
We secured additional support to waive the registration fee for at least 30 participants, which is especially beneficial for trainees
If interested, complete the form at the link below
August 21, 2025 at 5:42 PM
Great news about our upcoming meeting at Asilomar on the Ethics of Neural #Organoids and #Assembloids Research!
We secured additional support to waive the registration fee for at least 30 participants, which is especially beneficial for trainees
If interested, complete the form at the link below
We secured additional support to waive the registration fee for at least 30 participants, which is especially beneficial for trainees
If interested, complete the form at the link below
Reposted by Stanford Brain Organogenesis Center
Stem cell-derived neural organoids and assembloids are opening new frontiers in neuroscience, but what are the ethical and societal challenges?
Join the discussion at a meeting supported by @danafoundation.bsky.social and @brainorganogenesis.bsky.social.
🎟️ sto.stanfordtickets.org/ethical-and-...
Join the discussion at a meeting supported by @danafoundation.bsky.social and @brainorganogenesis.bsky.social.
🎟️ sto.stanfordtickets.org/ethical-and-...
August 4, 2025 at 8:11 PM
Stem cell-derived neural organoids and assembloids are opening new frontiers in neuroscience, but what are the ethical and societal challenges?
Join the discussion at a meeting supported by @danafoundation.bsky.social and @brainorganogenesis.bsky.social.
🎟️ sto.stanfordtickets.org/ethical-and-...
Join the discussion at a meeting supported by @danafoundation.bsky.social and @brainorganogenesis.bsky.social.
🎟️ sto.stanfordtickets.org/ethical-and-...
Check out the latest work on assembloids out in Science today 👇
Our latest work is out today in @science.org: a self-organizing system that models organizer-driven patterning and commissural axon guidance in human neural development.
Work led by Massimo Onesto with Neal Amin in the lab
Work led by Massimo Onesto with Neal Amin in the lab
July 17, 2025 at 8:55 PM
Check out the latest work on assembloids out in Science today 👇
Newest work in our Center 👇
Brain organoids are reshaping neuroscience. To scale up their work, Wu Tsai Neuro affiliates @sergiuppasca.bsky.social, Sarah Heilshorn & team found a solution: xanthan gum. This simple solution could accelerate the discovery of brain development & disease.
neuroscience.stanford.edu/news/common-...
neuroscience.stanford.edu/news/common-...
July 17, 2025 at 3:18 AM
Newest work in our Center 👇
Reposted by Stanford Brain Organogenesis Center
Sharing today the latest from our lab, just published in Nature Biomedical Engineering.
As stem cell models gain traction for disease modeling and drug testing, one of the bottlenecks has been scaling up production. In work led by Yuki and Genta, we present a simple and cost-effective solution.
As stem cell models gain traction for disease modeling and drug testing, one of the bottlenecks has been scaling up production. In work led by Yuki and Genta, we present a simple and cost-effective solution.
July 11, 2025 at 4:46 PM
Sharing today the latest from our lab, just published in Nature Biomedical Engineering.
As stem cell models gain traction for disease modeling and drug testing, one of the bottlenecks has been scaling up production. In work led by Yuki and Genta, we present a simple and cost-effective solution.
As stem cell models gain traction for disease modeling and drug testing, one of the bottlenecks has been scaling up production. In work led by Yuki and Genta, we present a simple and cost-effective solution.
Check out this exciting new meeting at Asilomar !
Excited to announce that applications are open for the Asilomar meeting on The Ethical and Societal Implications of Neural Organoids, Assembloids, and Their Transplantation!
As the technologies & applications of 3D neural models evolve, a number of ethical and societal issues are emerging.
As the technologies & applications of 3D neural models evolve, a number of ethical and societal issues are emerging.
July 8, 2025 at 8:17 PM
Check out this exciting new meeting at Asilomar !
Congratulations Massimo!
Thrilled to introduce the newest PhD from the lab—Dr. Massimo Onesto—who successfully defended his thesis @stanfordmedicine.bsky.social.
An exciting day for an exceptional scientist!
Behind is the now-traditional “assembloids cake” we put together for the occasion.
Congratulations, Massimo!
An exciting day for an exceptional scientist!
Behind is the now-traditional “assembloids cake” we put together for the occasion.
Congratulations, Massimo!
June 21, 2025 at 10:54 PM
Congratulations Massimo!
Reposted by Stanford Brain Organogenesis Center
A few weeks ago, I talked to @neildegrassetyson.com on his StarTalk Radio about our efforts to understand human brain disorders with stem cell models including #assembloids. We touched on the promise of these technologies, the challenges & the mission behind the work
www.youtube.com/watch?v=HEBj...
www.youtube.com/watch?v=HEBj...
Groundbreaking Studies Recreate Human Brain Circuits in a Dish
YouTube video by StarTalk
www.youtube.com
June 4, 2025 at 7:50 PM
A few weeks ago, I talked to @neildegrassetyson.com on his StarTalk Radio about our efforts to understand human brain disorders with stem cell models including #assembloids. We touched on the promise of these technologies, the challenges & the mission behind the work
www.youtube.com/watch?v=HEBj...
www.youtube.com/watch?v=HEBj...
Congratulations, XiangLing! And thank you for all your contributions to our Center and the international courses 🙏
This is a bittersweet week as we say goodbye to a phenomenal postdoc in the lab— Xiangling Meng—who is leaving to start her own independent lab at Baylor College of Medicine.
May 14, 2025 at 3:01 PM
Congratulations, XiangLing! And thank you for all your contributions to our Center and the international courses 🙏
Exciting week for us here in the Center hosting students from all over the world!
This week we welcome on campus 2025 class of students for our hands-on Stanford Brain Organogenesis course.
With students joining from across the globe, this is our most international class yet—diving into cutting-edge neural #organoid and #assembloid methods, ready to bring them back to their labs.
With students joining from across the globe, this is our most international class yet—diving into cutting-edge neural #organoid and #assembloid methods, ready to bring them back to their labs.
May 7, 2025 at 6:24 PM
Exciting week for us here in the Center hosting students from all over the world!
Check out this overview of human stem cell models of brain development and disease
What human experimental models do we currently have to study brain disorders—and where do they fall short?
In our recent @annualreviews.bsky.social, @rebeccalevymdphd.bsky.social and I examine the landscape of human stem cell models—2D systems, 3D #organoids, #assembloids, and transplantation.
In our recent @annualreviews.bsky.social, @rebeccalevymdphd.bsky.social and I examine the landscape of human stem cell models—2D systems, 3D #organoids, #assembloids, and transplantation.
May 6, 2025 at 9:30 PM
Check out this overview of human stem cell models of brain development and disease
Reposted by Stanford Brain Organogenesis Center
Second day of 2025 Stanford Brain Organogenesis is on full steam! 🚂 @rebeccalevymdphd.bsky.social @sergiuppasca.bsky.social @brainorganogenesis.bsky.social
May 6, 2025 at 4:49 PM
Second day of 2025 Stanford Brain Organogenesis is on full steam! 🚂 @rebeccalevymdphd.bsky.social @sergiuppasca.bsky.social @brainorganogenesis.bsky.social
Great summary on @npr.org by Jon Hamilton discussing the recent reconstruction of the sensory neural pathway in #assembloids reported this week by our Director @sergiuppasca.bsky.social lab at @stanfordmedicine.bsky.social
www.npr.org/sections/sho...
www.npr.org/sections/sho...
Pain pathway in a dish could aid search for new analgesic drugs
Scientists have recreated a pathway that senses pain, using clusters of human nerve cells grown in a dish.
www.npr.org
April 11, 2025 at 5:40 PM
Great summary on @npr.org by Jon Hamilton discussing the recent reconstruction of the sensory neural pathway in #assembloids reported this week by our Director @sergiuppasca.bsky.social lab at @stanfordmedicine.bsky.social
www.npr.org/sections/sho...
www.npr.org/sections/sho...
Reposted by Stanford Brain Organogenesis Center
The @sergiuppasca.bsky.social group functionally assembled the essential components of the human sensory pathway in a compound organoid "assembloid." The model could accelerate our understanding of sensory circuits and facilitate therapeutic development. ow.ly/BZ4R50VxSfy 🧪 @gregscherrer.bsky.social
April 10, 2025 at 7:03 PM
The @sergiuppasca.bsky.social group functionally assembled the essential components of the human sensory pathway in a compound organoid "assembloid." The model could accelerate our understanding of sensory circuits and facilitate therapeutic development. ow.ly/BZ4R50VxSfy 🧪 @gregscherrer.bsky.social
Great overview of the recent @nature.com article from the Pasca lab
Brief overview in @data.ft.com of recent work to build four-part assembloids as a model of the human somatosensory neural pathway
www.ft.com/content/f8d5...
www.ft.com/content/f8d5...
Scientists recreate brain circuit in lab for first time
Research breakthrough promises new treatments for severe pain
www.ft.com
April 10, 2025 at 10:38 PM
Great overview of the recent @nature.com article from the Pasca lab
Exciting new research today in @nature.com from @sergiuppasca.bsky.social’s lab
In @nature.com today we report sensory #assembloids comprising four parts to recapitulate aspects of the pathway that processes pain stimuli and we use it to study genetic syndromes.
Work pioneered by the brilliant Ji-il Kim & Kent Imaizumi in close collab with @gregscherrer.bsky.social !
Link 👇
Work pioneered by the brilliant Ji-il Kim & Kent Imaizumi in close collab with @gregscherrer.bsky.social !
Link 👇
April 9, 2025 at 6:17 PM
Exciting new research today in @nature.com from @sergiuppasca.bsky.social’s lab
Check out this brief summary
As stem cell-based modeling of the human nervous system and disease advances, we recently shared a group-effort framework in @nature.com on designing experiments with #organoids, #assembloids, and transplantation
Here a few key takeaways in 6 slides👇
Here a few key takeaways in 6 slides👇
April 4, 2025 at 7:40 PM
Check out this brief summary
Congratulations to our Director @sergiuppasca.bsky.social for his induction into the American Institute for Medical and Biological Engineering @aimbe-official.bsky.social this week in Washington DC!
April 1, 2025 at 11:50 PM
Congratulations to our Director @sergiuppasca.bsky.social for his induction into the American Institute for Medical and Biological Engineering @aimbe-official.bsky.social this week in Washington DC!
Congratulations on this important group effort!
In this week’s @nature.com, we publish a group effort to outline a framework for studies with neural #organoids, #assembloids and transplantation. More details below 1/n
March 15, 2025 at 4:43 AM
Congratulations on this important group effort!