Super pleased to have finally published our latest neurochemistry review on the many and varied roles of aspartate in brain.
rdcu.be/eqMHd

New paper showing a key component of the glutamate-glutamine cycle. NTT4 (SLC6A17) supplies Gln for the presynaptic production of Glu. Needed to sustain rapid ongoing excitatory synaptic transmission and has roles in memory formation and other behaviours.
doi.org/10.1016/j.pneurobio.2025.102785

Fantastic @neurochemistry.org sponsored talk at Society of Neuroscientists in Africa from Rosa Cossart. Detecting a body size dependent developmental switch in the GABAergic hippocampus which is disrupted in an #autism model.
#SONA2025

Sodium dysregulation may play a role in Alzheimer's disease with links to increased amyloid-dependent tau pathology, neurodegeneration, and cognitive impairment. Sodium channel subunits (SCN2B &3B) showed strongest correlation with hippocampal volume and cognitive function
doi.org/10.1111/jnc....

Latest issue of ISN News is out and available to read online. Includes advice on responding to reviewers from @drbreaky.bsky.social
www.neurochemistry.org/isn-news-02/