Benedetto Polimeni
bpoli.bsky.social
Benedetto Polimeni
@bpoli.bsky.social
Postdoctoral researcher at Bodega lab, INGM, Milan | #bioinformatics, #genomics, retro- #transposons.
Reposted by Benedetto Polimeni
Finally out! 🥳 Our paper showing how a transposable element (TE) insertion can cause developmental phenotypes is now published @natgenet.nature.com 🧬🦠🐁
Below is a brief description of the major findings. Check the full version of the paper for more details: www.nature.com/articles/s41588-025-02248-5
Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes - Nature Genetics
Activation of an LTR retrotransposon inserted upstream of the Fgf8 gene produces viral-like particles in the mouse developing limb, triggering apoptosis and causing limb malformation. This phenotype c...
www.nature.com
July 9, 2025 at 10:05 AM
Reposted by Benedetto Polimeni
Yes, but can it run Doom?

`nextflow run doom`

@nextflow.io (by @jordeu.bsky.social 🌟)
github.com/nextflow-io/...
January 22, 2025 at 8:11 AM
Reposted by Benedetto Polimeni
If there's something we don't understand I assume transposons are responsible unless proven otherwise
January 18, 2025 at 6:23 PM