Bonnie Lee
@bonniee-leee.bsky.social
PhD in Neuroscience | Postdoctoral Fellow at @camhnews.bsky.social & @whrcluster.bsky.social
@istaart.bsky.social Ambassador Alumni
🧠 women’s health, sex differences, Alzheimer’s disease, brain & cognitive aging
https://www.galealab.com/bonnielee
@istaart.bsky.social Ambassador Alumni
🧠 women’s health, sex differences, Alzheimer’s disease, brain & cognitive aging
https://www.galealab.com/bonnielee
doi.org/10.1016/j.bb...
We found paradoxical effects of a previous pregnancy on the middle-aged brain depending on APOEe4 (genetic risk for late-onset Alzheimer’s disease) 🐁
I’ll be presenting some of this work and a follow-up study on Mon at 2pm during our FRS symposium at #AAIC25! Come say hi!! 👋
We found paradoxical effects of a previous pregnancy on the middle-aged brain depending on APOEe4 (genetic risk for late-onset Alzheimer’s disease) 🐁
I’ll be presenting some of this work and a follow-up study on Mon at 2pm during our FRS symposium at #AAIC25! Come say hi!! 👋
Redirecting
doi.org
July 26, 2025 at 7:39 PM
doi.org/10.1016/j.bb...
We found paradoxical effects of a previous pregnancy on the middle-aged brain depending on APOEe4 (genetic risk for late-onset Alzheimer’s disease) 🐁
I’ll be presenting some of this work and a follow-up study on Mon at 2pm during our FRS symposium at #AAIC25! Come say hi!! 👋
We found paradoxical effects of a previous pregnancy on the middle-aged brain depending on APOEe4 (genetic risk for late-onset Alzheimer’s disease) 🐁
I’ll be presenting some of this work and a follow-up study on Mon at 2pm during our FRS symposium at #AAIC25! Come say hi!! 👋
Ahhh!! Congrats to us 😜🥹
May 22, 2025 at 4:53 AM
Ahhh!! Congrats to us 😜🥹
Congrats Jenn!!! 🥳
April 11, 2025 at 9:09 PM
Congrats Jenn!!! 🥳
But... is this really the whole picture? What if our current understanding is biased toward knowledge from male models?
This work highlights the urgent need to examine how and why AD develops differently across sex. Understanding these differences will lead to better, more effective treatments.
This work highlights the urgent need to examine how and why AD develops differently across sex. Understanding these differences will lead to better, more effective treatments.
February 11, 2025 at 8:06 PM
But... is this really the whole picture? What if our current understanding is biased toward knowledge from male models?
This work highlights the urgent need to examine how and why AD develops differently across sex. Understanding these differences will lead to better, more effective treatments.
This work highlights the urgent need to examine how and why AD develops differently across sex. Understanding these differences will lead to better, more effective treatments.
This latest study reveals that male rats with a genetic risk for AD show changes in markers related to brain health that "make sense" - reduced neural stem cells and neurogenesis, which was associated with increased microglia - yet female rats showed completely different patterns of effects.
February 11, 2025 at 8:06 PM
This latest study reveals that male rats with a genetic risk for AD show changes in markers related to brain health that "make sense" - reduced neural stem cells and neurogenesis, which was associated with increased microglia - yet female rats showed completely different patterns of effects.
Alzheimer’s disease (AD) disproportionately affects females, yet most research has focused on male models or not investigated the potential influences of sex. This has left critical gaps in our understanding of how AD risk and progression might be different across sexes.
February 11, 2025 at 8:06 PM
Alzheimer’s disease (AD) disproportionately affects females, yet most research has focused on male models or not investigated the potential influences of sex. This has left critical gaps in our understanding of how AD risk and progression might be different across sexes.