Michael J. Robertson
@biophysicsguy.bsky.social
Assistant Professor in Biochemistry & Molecular Pharmacology, Baylor College of Medicine. CryoEM, GPCRs, Membrane Proteins, Comp Chem, SBDD.
Excited to share our latest preprint! We used cryoEM and MD simulations to look at the GTP-induced activation of the mu-opioid receptor-Gi complex with partial, full, & super agonists resolving the landscape of Gi activation and how its modulated by different ligands!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
June 2, 2025 at 1:32 PM
Excited to share our latest preprint! We used cryoEM and MD simulations to look at the GTP-induced activation of the mu-opioid receptor-Gi complex with partial, full, & super agonists resolving the landscape of Gi activation and how its modulated by different ligands!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...