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naturepoker
@binomicalabs.org
Binomica Labs independent researcher by day, warehouse worker by night

Small thoughtful science

#phylogenetics #archaea #evolution #bioinformatics

@naturepoker@genomic.social
http://naturepoker.wordpress.com
https://orcid.org/0000-0002-6977-5440
Current premises of 'de-extinction' has a strong modern safari for the affluent vibe, IMHO.
November 11, 2025 at 12:57 AM
I hope so - otherwise this is too depressing!
November 10, 2025 at 10:24 PM
Nice Minolta SLR! I love 110 film too, though I stick with BW and hand-develop with caffenol to keep it cheap.

Haha I'll try my best to stick with 660, keep my eyes on sx70 in the future
November 8, 2025 at 11:15 PM
Hmm you're right - maybe I should just keep an eye open and pick one up on the cheap, even if refurb needs to wait. The best instant camera ever made aren't going to be around forever.
November 8, 2025 at 11:05 PM
Ah, that's the camera I'll dream about for a long while. Factoring in CLA and 600 conversion, prices are high and rising, it looks like.
November 8, 2025 at 10:50 PM
Thank you! All the shots so far managed to impress - I think I really need to start saving up for the film.
November 8, 2025 at 10:16 PM
Reposted by naturepoker
Fantastic talk by @vikramshivakumar.bsky.social Mumemto—Scalable multi-MUM finding for pangenomes
Papers biorxiv.org/content/10.1101/2025.05.20.654611 & doi.org/10.1186/s13059-025-03644-0
Code: github.com/vikshiv/mume...
Very efficient pangenome visualization tool, revealing synteny and variations!
November 6, 2025 at 1:13 AM
I build an ML tree using Haladaptatus outgroup against existing Halococcus species (single copy genes based, 308 targets), and it does seem to place in middle of other Halococcus species with great bootstrap values.
November 6, 2025 at 7:04 PM
I think that's the point where I get all the side eyes from my collaborators lol
November 6, 2025 at 5:24 PM
oooh cool name. I was also thinking something quadra related from the cocci packing. Also as Gunnm reference
November 6, 2025 at 5:20 PM
I also decided to make doubly sure, so got some detailed microscopy from collaborators and should be getting gas chromatography analysis sometime. Getting some practice on academia-amateur collaboration pipeline in the process as well :)
November 6, 2025 at 5:11 PM
Reasonably certain this is a novel species - originally collected as part of a Halococcus-wide resequencing & methylation analysis project I ran (paper coming soon 🤞). The conventional biomarker genes, genomic structural arrangement and SCG based trees all set it apart from others of the genus
November 6, 2025 at 5:10 PM
Ohh good one. These guys seem to dissolve into agglomerates under specific growth conditions too.

It'll likely be what you described or one of the older researchers (from 70's I think) associated with history of this one, whatever is more appropriate.
November 6, 2025 at 5:04 PM
I like it, accurate and to the point!
November 6, 2025 at 5:01 PM