naturepoker
@binomicalabs.org
Binomica Labs independent researcher by day, warehouse worker by night
Small thoughtful science
#phylogenetics #archaea #evolution #bioinformatics
@naturepoker@genomic.social
http://naturepoker.wordpress.com
https://orcid.org/0000-0002-6977-5440
Small thoughtful science
#phylogenetics #archaea #evolution #bioinformatics
@naturepoker@genomic.social
http://naturepoker.wordpress.com
https://orcid.org/0000-0002-6977-5440
Please tell me this is just a wild guess. Democrats decided to cave in because successfully defending ACA coverage will get rid of a talking point in the midterms?
newrepublic.com/post/202948/...
newrepublic.com/post/202948/...
November 10, 2025 at 9:37 PM
Please tell me this is just a wild guess. Democrats decided to cave in because successfully defending ACA coverage will get rid of a talking point in the midterms?
newrepublic.com/post/202948/...
newrepublic.com/post/202948/...
Picked up a #Polaroid Sun660 from a curve sale for pocket change. Very happy to see it's working properly with fresh film!
Doubly glad to capture the last of the autumn leaves - I was afraid I wouldn't be able to take them before the rains washed them away.
#analogphotography
Doubly glad to capture the last of the autumn leaves - I was afraid I wouldn't be able to take them before the rains washed them away.
#analogphotography
November 8, 2025 at 9:58 PM
Picked up a #Polaroid Sun660 from a curve sale for pocket change. Very happy to see it's working properly with fresh film!
Doubly glad to capture the last of the autumn leaves - I was afraid I wouldn't be able to take them before the rains washed them away.
#analogphotography
Doubly glad to capture the last of the autumn leaves - I was afraid I wouldn't be able to take them before the rains washed them away.
#analogphotography
Ok I think I'm set for the winter.
November 7, 2025 at 10:50 PM
Ok I think I'm set for the winter.
Check this out - first image of a new Halococcus species I discovered with collaborators. Still figuring out the scheme to name the darn thing.
Independent research & amateur biology FTW.
🧫🦠🧪
Independent research & amateur biology FTW.
🧫🦠🧪
November 6, 2025 at 4:52 PM
Check this out - first image of a new Halococcus species I discovered with collaborators. Still figuring out the scheme to name the darn thing.
Independent research & amateur biology FTW.
🧫🦠🧪
Independent research & amateur biology FTW.
🧫🦠🧪
Going through @samuelhorsfield.bsky.social presentation on pangenome graphs in comparative genomics, courtesy of @training.ebi.embl.org.
Fascinating tidbit on history of alignment based sequence graph - it goes all the way back to 1989 (Hein), era of Apple IIs and IBM PS/2s. Great talk!
💻🧬🦠🧫
Fascinating tidbit on history of alignment based sequence graph - it goes all the way back to 1989 (Hein), era of Apple IIs and IBM PS/2s. Great talk!
💻🧬🦠🧫
November 5, 2025 at 3:19 PM
Going through @samuelhorsfield.bsky.social presentation on pangenome graphs in comparative genomics, courtesy of @training.ebi.embl.org.
Fascinating tidbit on history of alignment based sequence graph - it goes all the way back to 1989 (Hein), era of Apple IIs and IBM PS/2s. Great talk!
💻🧬🦠🧫
Fascinating tidbit on history of alignment based sequence graph - it goes all the way back to 1989 (Hein), era of Apple IIs and IBM PS/2s. Great talk!
💻🧬🦠🧫
오랜만에 눈마새를 정독중에 이 부분을 다시 읽었다.
자기완성을 위한 인생을 조심하라. 나중에 라수가 독자를 위해 풀이해 줄때 까지 정말 알쏭달쏭한 문장이었는데.
젠장. 한국밖의 사람들이 이 소설을 읽지 못하고 살아가야 한다는 사실은 굉장한 불의가 아닐 수 없다.
그럼, 내가 모르는 언어와 문화들의 시와 이야기들도 이처럼 재미있고 인생들을 흔들어 놓는 존재들 이라는 것이겠지.
인생이 어둡고 갑갑해질때 이런 생각을 하면 좀 가슴이 시원해지는 느낌이 든다.
자기완성을 위한 인생을 조심하라. 나중에 라수가 독자를 위해 풀이해 줄때 까지 정말 알쏭달쏭한 문장이었는데.
젠장. 한국밖의 사람들이 이 소설을 읽지 못하고 살아가야 한다는 사실은 굉장한 불의가 아닐 수 없다.
그럼, 내가 모르는 언어와 문화들의 시와 이야기들도 이처럼 재미있고 인생들을 흔들어 놓는 존재들 이라는 것이겠지.
인생이 어둡고 갑갑해질때 이런 생각을 하면 좀 가슴이 시원해지는 느낌이 든다.
October 26, 2025 at 12:09 AM
오랜만에 눈마새를 정독중에 이 부분을 다시 읽었다.
자기완성을 위한 인생을 조심하라. 나중에 라수가 독자를 위해 풀이해 줄때 까지 정말 알쏭달쏭한 문장이었는데.
젠장. 한국밖의 사람들이 이 소설을 읽지 못하고 살아가야 한다는 사실은 굉장한 불의가 아닐 수 없다.
그럼, 내가 모르는 언어와 문화들의 시와 이야기들도 이처럼 재미있고 인생들을 흔들어 놓는 존재들 이라는 것이겠지.
인생이 어둡고 갑갑해질때 이런 생각을 하면 좀 가슴이 시원해지는 느낌이 든다.
자기완성을 위한 인생을 조심하라. 나중에 라수가 독자를 위해 풀이해 줄때 까지 정말 알쏭달쏭한 문장이었는데.
젠장. 한국밖의 사람들이 이 소설을 읽지 못하고 살아가야 한다는 사실은 굉장한 불의가 아닐 수 없다.
그럼, 내가 모르는 언어와 문화들의 시와 이야기들도 이처럼 재미있고 인생들을 흔들어 놓는 존재들 이라는 것이겠지.
인생이 어둡고 갑갑해질때 이런 생각을 하면 좀 가슴이 시원해지는 느낌이 든다.
This makes surprising amount of sense.
October 25, 2025 at 2:22 AM
This makes surprising amount of sense.
Another fun #archaeasky paper to ponder about. HGT driven copy number expansion led to structural diversification, collection of which ended up being the eukaryotic replisome - seems to be the gist, as demonstrated by the author's very handy illustration.
🦠🧫
🦠🧫
October 21, 2025 at 6:58 PM
Another fun #archaeasky paper to ponder about. HGT driven copy number expansion led to structural diversification, collection of which ended up being the eukaryotic replisome - seems to be the gist, as demonstrated by the author's very handy illustration.
🦠🧫
🦠🧫
Depravity pervading through our generation in one image.
Found during random browsing.
Found during random browsing.
October 21, 2025 at 1:05 AM
Depravity pervading through our generation in one image.
Found during random browsing.
Found during random browsing.
This sits at the highest place in my lab lol
October 17, 2025 at 1:17 PM
This sits at the highest place in my lab lol
This particular figure was quite striking - physical microscopy of the E. coli genome. Somehow we run these tangles mess through pores (often not breaking them over significant distances) and render them into reliable representation of whole genomic compartments.
🧫🦠
🧫🦠
October 15, 2025 at 2:25 PM
This particular figure was quite striking - physical microscopy of the E. coli genome. Somehow we run these tangles mess through pores (often not breaking them over significant distances) and render them into reliable representation of whole genomic compartments.
🧫🦠
🧫🦠
There's another artists collective building right across the street from our lab with fascinating murals wrapping around the walls. Alas, the owners got rid of the whole thing yesterday - it's just a gray block now 😞
These photos turned out to be the paintings in their final few days
#nyc
These photos turned out to be the paintings in their final few days
#nyc
October 6, 2025 at 12:09 AM
There's another artists collective building right across the street from our lab with fascinating murals wrapping around the walls. Alas, the owners got rid of the whole thing yesterday - it's just a gray block now 😞
These photos turned out to be the paintings in their final few days
#nyc
These photos turned out to be the paintings in their final few days
#nyc
Taking a breather from a long exhausting day. Reminds me I need to go back to the lab and build some heatmaps.
October 2, 2025 at 10:58 PM
Taking a breather from a long exhausting day. Reminds me I need to go back to the lab and build some heatmaps.
Man this one's a trip down the memory lane. One of more surreal experiences in my life was sorting through mislabeled mummies in the old Cairo museum of antiquities, surrounded by burning smoke of their ministry of information building - right after the Tahrir square incident.
September 25, 2025 at 8:40 PM
Man this one's a trip down the memory lane. One of more surreal experiences in my life was sorting through mislabeled mummies in the old Cairo museum of antiquities, surrounded by burning smoke of their ministry of information building - right after the Tahrir square incident.
Your last saved picture is your moral philosophy
I'm confused.
I'm confused.
September 7, 2025 at 4:07 PM
Your last saved picture is your moral philosophy
I'm confused.
I'm confused.
I think I finally untangled this darn Archaeal genome. About three full days of work building some middleware. Good grief, I had an easier time assembling rabbit neuron rna-seq reads and running PCA on it. Before and after graph for the Archaea, final product's fully circularized.
September 5, 2025 at 7:19 PM
I think I finally untangled this darn Archaeal genome. About three full days of work building some middleware. Good grief, I had an easier time assembling rabbit neuron rna-seq reads and running PCA on it. Before and after graph for the Archaea, final product's fully circularized.
Testing out stand caffenol development. While regular agitation is far faster (15 min vs 1 hour) I get to leave the film in the developer and go work for a while with the stand method, potentially using multiple containers at once.
ISO100 120 frame from a Holga. Doesn't look half bad!
ISO100 120 frame from a Holga. Doesn't look half bad!
August 20, 2025 at 3:28 AM
Testing out stand caffenol development. While regular agitation is far faster (15 min vs 1 hour) I get to leave the film in the developer and go work for a while with the stand method, potentially using multiple containers at once.
ISO100 120 frame from a Holga. Doesn't look half bad!
ISO100 120 frame from a Holga. Doesn't look half bad!
The late afternoon stroll through the used book row was definitely worth it today.
August 19, 2025 at 11:55 PM
The late afternoon stroll through the used book row was definitely worth it today.
Finally making time to read Greg Priest's amazing history of science dissertation "Charles Darwin's Science of History". Chapter 1 ends with phrasing below:
I find the static genes-are-circuits paradigm of synbio too divorced from biological reality. Was there another path? I guess we'll see!
I find the static genes-are-circuits paradigm of synbio too divorced from biological reality. Was there another path? I guess we'll see!
August 19, 2025 at 6:41 PM
Finally making time to read Greg Priest's amazing history of science dissertation "Charles Darwin's Science of History". Chapter 1 ends with phrasing below:
I find the static genes-are-circuits paradigm of synbio too divorced from biological reality. Was there another path? I guess we'll see!
I find the static genes-are-circuits paradigm of synbio too divorced from biological reality. Was there another path? I guess we'll see!
Rigging up a spare phone into 16mm film scanning and curve inverting duty. The smaller film format has its limits, but is still capable of producing pretty decent results. I buy expired microfilm or 16mm movie stock and load them manually, cost per shot can go down to 15 cents or so.
August 16, 2025 at 3:40 PM
Rigging up a spare phone into 16mm film scanning and curve inverting duty. The smaller film format has its limits, but is still capable of producing pretty decent results. I buy expired microfilm or 16mm movie stock and load them manually, cost per shot can go down to 15 cents or so.
The 16mm films I took to ASM 2025 developed beautifully in caffenol. I wasn't sure how it would turn out from lack of practice and new 16mm reel being a little fiddly, but it turned out okay. Woot
August 15, 2025 at 11:35 PM
The 16mm films I took to ASM 2025 developed beautifully in caffenol. I wasn't sure how it would turn out from lack of practice and new 16mm reel being a little fiddly, but it turned out okay. Woot