Billy Marsiglia
@billymarsiglia.bsky.social
Assistant Professor and Chemical Biologist at UAB studying protein-protein interactions in the PI3K-AKT pathway. He/him
marsiglialab.com
marsiglialab.com
We found that T308 phosphorylation allosterically enhances the binding of ATP-competitive inhibitors and influences their effectiveness on triple-negative cancer cell lines. Great work done by Jeremy Harris, Dr. Flávio Antônio de Oliveira Simões, and Erin Ryerson!
March 24, 2025 at 3:44 PM
We found that T308 phosphorylation allosterically enhances the binding of ATP-competitive inhibitors and influences their effectiveness on triple-negative cancer cell lines. Great work done by Jeremy Harris, Dr. Flávio Antônio de Oliveira Simões, and Erin Ryerson!