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bic-bordeaux.bsky.social
BIC_Bordeaux
@bic-bordeaux.bsky.social
Imaging facility located in Bordeaux. We offer service in light and electron microscopy, and in image treatment and analyse.
November #ImageOfTheMonth goes to M.Pujol from LPCO lab (UMR 5629). Acquired with Transmission Electron Microscopy, it shows a polystyrene (PS) latex obtained by post-dispersion of a yogurt cup made of PS in water using a surfactant. The resulting particles are highly heterogeneous and large.
November 3, 2025 at 11:02 AM
‪October #ImageOfTheMonth is from O. Barba-Vila from @iins-bordeaux.bsky.social Slice of the gustatory cortex showing axons from the gustatory thalamus (G), basolateral amygdala (R) and a thick-tufted layer 5 neuron (W), recorded through patch clamp and imaged via biocytin-streptavidin labelling
October 7, 2025 at 7:48 AM
September #ImageOfTheMonth is from @rkinet.bsky.social from @imn-bordeaux.bsky.social
This is a maximum projection of a confocal image of a microglia cell (blue) and its nucleus (red), internalising multiple nanoparticles (yellow), one day after supranigral injection in C57B6-J mouse
September 8, 2025 at 9:09 AM
August #ImageOfTheMonth is from L.Congiu from
@imn-bordeaux.bsky.social. This is a 3D reconstruction of a CD68-positive particles (white) within the cell body of microglia cells (Red) in the mouse cortex. The confocal Z-stack was processed with Imaris software.
August 7, 2025 at 6:56 PM
Reposted by BIC_Bordeaux
It’s good to be back at the BIC! @bic-bordeaux.bsky.social 🔬
July 23, 2025 at 3:31 PM
July #ImageOfTheMonth is from A.Drouet from
@iins-bordeaux.bsky.social. This image represents a neurosphere (150x150 µm) formed from dissociated hippocampal neurons cultured for 14 days under non-adhesive conditions. Yellow shows GFP expressing neurons and nuclei are showed in cyan.
July 4, 2025 at 9:36 AM
A detailed map of mouse brain cell structure & connections, offering insights into how they relate to activity in the brain, is revealed in papers from MICrONS consortium: http://spklr.io/63327B6slL

@alleninstitute.org @natureportfolio.nature.com @natmethods.nature.com @nature.com
#Neuroscience
June 17, 2025 at 12:53 PM
June #ImageOfTheMonth is from L.Boutaleb from @inrae-bfp.bsky.social. They study the impact of heat stress on cell division and DNA replication on the tomato meristem. On this confocal image, EdU staining (magenta) detects replicating DNA and Hoechst labeling (cyan) shows all cell nuclei.
June 5, 2025 at 8:50 AM
May #ImageOfTheMonth was from C.Mazocco & M.Darricau from @imn-bordeaux.bsky.social. Staining on spinal cord slices reveal TDP43 protein in the nucleus of neurons (Red). Motoneurons and synaptic terminations were stained targetting ChAT (Cyan).
June 5, 2025 at 8:44 AM
Reposted by BIC_Bordeaux
Time to expand your vision! 👀🌱
Our latest work on ExM in plants is out
Back-to-back with the Danzl 's lab (@ISTAustria) led by Magali Grison @lbm-bordeaux.bsky.social with @monica-bic.bsky.social and @gmaucort.bsky.social from the @bic-bordeaux.bsky.social .

academic.oup.com/plcell/artic...
April 17, 2025 at 8:49 AM
Reposted by BIC_Bordeaux
Finally out!, after a few months of delay, our protocol on ExM in plant roots is now available in The Plant Cell
academic.oup.com/plcell/artic...
Beautiful images in a great collaboration of the @bic-bordeaux.bsky.social with @emmanuellebayer.bsky.social and Magali Grison @lbm-bordeaux.bsky.social
Root expansion microscopy: A robust method for super resolution imaging in Arabidopsis
Root expansion microscopy (ROOT-ExM) achieves super-resolution expansion microscopy in plants.
academic.oup.com
April 14, 2025 at 9:47 AM
April #ImageOfTheMonth is from H. Vaïtinadapoulé (BiiO EA 2521). Here is a guttae, a “drop-like deposits” of extracellular matrix components on the surface of the cornea. This image was acquired using scanning electron microscopy with the help of F.Decoeur from the EM unit of the BIC.
April 1, 2025 at 4:19 PM
March #ImageOfTheMonth goes to M.Bonhivers from MFP lab (UMR 5234).
Trypanosoma brucei cell was extracted in detergent, expanded 4.2 fold using U-ExM, labelled for the microtubule cytoskeleton (magenta) and for the Hook Complex (yellow), and images usinf scanning confocal microscopy.
March 3, 2025 at 11:00 AM
Reposted by BIC_Bordeaux
Super-resolution microscopy unravels a dynamic tubular network that is stabilized by pre-existing Golgi and lipids to mature into new Golgi pre-cisternae, @bic-bordeaux.bsky.social, @cnrsbiologie.bsky.social, @cnrsaquitaine.bsky.social, #Lipids, #ExpansionMicroscopy, #PlantScience, #PlantCellBiology
February 25, 2025 at 10:11 AM
Reposted by BIC_Bordeaux
Save the date !
Frontiers in Neurophotonics Symposium 2025 in Bordeaux
October 6-9
frontiersneurophotonics.org/2025-speakers/
🧪
2025 Speakers – International Frontiers in Neurophotonics Symposium
frontiersneurophotonics.org
February 5, 2025 at 2:08 PM
February #ImageOfTheMonth is from
@tdhellemmes.bsky.social
. GFP expressing Relaxin3 neurons from the nucleus incertus and their projections are followed through the whole mouse brain using Adipoclear+ method and Light Sheet microscopy. Scale:1mm
February 3, 2025 at 5:01 PM
Happy new year! Let's start 2025 with an #ImageOfTheMonth from N. Bollier @inrae-bfp.bsky.social. Scanning confocal 3D reconstruction of a tomato shoot apical meristem. The fixed meristem was cleared using clearsee and the cell walls are stained by calcofluor white.
January 5, 2025 at 3:38 PM
Reposted by BIC_Bordeaux
Kaleidoscopic view of my tracing experiment, from top to bottom.

Our great achievement with @jeremie-bic.bsky.social in @bic-bordeaux.bsky.social for @imn-bordeaux.bsky.social
December 30, 2024 at 4:27 PM
Reposted by BIC_Bordeaux
Icing stars and flowers in electron microscopy.

With the courtesy of Isabelle Svahn in @neurobordeaux.bsky.social and @bic-bordeaux.bsky.social
December 29, 2024 at 2:56 PM
Hello, the BIC is starting its Bluesky experience with its December #ImageOfTheMonth. Beautiful rat neurons imaged in STED 😍 by T.Cloâtre from @iins-bordeaux.bsky.social !
December 12, 2024 at 10:30 AM
For Christmas this year the BIC asked for a new 🔬booking website and Santa heard us 😊. So now we are asking our users to help us find it the best name. If you have ideas and want to participate please help yourself:

forms.gle/GBJ3zymegDSr8p…
December 12, 2024 at 10:22 AM
The BIC wishes you all a very happy new year 2023!
To start well this new year, here is our January newsletter 😊:

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December 12, 2024 at 10:22 AM
Le BIC vous souhaite de bonnes fêtes de fin d'année !
December 12, 2024 at 10:22 AM
Aujourd'hui le BIC reçoit le cristal collectif du CNRS. Tous les membres de l'équipe tiennent à remercier les utilisateurs grâce à qui nous évoluons au quotidien.
Félicitations aux autres Lauréats aquitains des #TalentsCNRS !
December 12, 2024 at 10:22 AM
Our December newsletter is out 😊

bic.u-bordeaux.fr/?mailpoet_rout…
December 12, 2024 at 10:22 AM