Benedikt Sundermann
@benediktsun.bsky.social
Neuroradiology, fMRI, and growing interest in advanced neurovascular MRI. Oldenburg, Germany. (previously Münster & Oxford). Writing and sharing on my own behalf, mainly for scientific discussions and #RadEd
Pinned
1/3 Ever wondered how the individual cortical #ASPECTS regions routinely assessed in acute #stroke imaging are related to functional #brain #networks? We have now addressed this with an atlas correspondence analysis. See our brief report preprint at doi.org/10.1101/2025...
Reposted by Benedikt Sundermann
Big data won't solve anything if it's crappy data. 😒
We need to 1) train people to inspect datasets before using them and 2) ensure that openly shared data is good data.
www.thetransmitter.org/spectrum/poo...
We need to 1) train people to inspect datasets before using them and 2) ensure that openly shared data is good data.
www.thetransmitter.org/spectrum/poo...
Poor image quality introduces systematic bias into MRI data
Analyses that include low-quality MRI data underestimate cortical thickness and overestimate surface area, according to new work from the ABCD Study.
www.thetransmitter.org
August 1, 2025 at 11:36 PM
Big data won't solve anything if it's crappy data. 😒
We need to 1) train people to inspect datasets before using them and 2) ensure that openly shared data is good data.
www.thetransmitter.org/spectrum/poo...
We need to 1) train people to inspect datasets before using them and 2) ensure that openly shared data is good data.
www.thetransmitter.org/spectrum/poo...
Reposted by Benedikt Sundermann
My dissertation / first RR is out now in Imaging Neuroscience! Lots of folks discuss how between-person heterogeneity may limit the utility of group-averages for brain functioning - we empirically tested that idea! doi.org/10.1162/IMAG...
July 28, 2025 at 9:36 PM
My dissertation / first RR is out now in Imaging Neuroscience! Lots of folks discuss how between-person heterogeneity may limit the utility of group-averages for brain functioning - we empirically tested that idea! doi.org/10.1162/IMAG...
Reposted by Benedikt Sundermann
👀
Using Extreme Value Statistics to Reconceptualize Psychopathology as Extreme Deviations From a Normative Reference Model
onlinelibrary.wiley.com/doi/full/10....
Using Extreme Value Statistics to Reconceptualize Psychopathology as Extreme Deviations From a Normative Reference Model
onlinelibrary.wiley.com/doi/full/10....
Using Extreme Value Statistics to Reconceptualize Psychopathology as Extreme Deviations From a Normative Reference Model
Overview of our approach for extreme value statistics. First, we fit a normative model to imaging phenotypes, before employing a ‘peaks-over-threshold’ approach widely used in meteorology and finance....
onlinelibrary.wiley.com
July 21, 2025 at 12:30 AM
👀
Using Extreme Value Statistics to Reconceptualize Psychopathology as Extreme Deviations From a Normative Reference Model
onlinelibrary.wiley.com/doi/full/10....
Using Extreme Value Statistics to Reconceptualize Psychopathology as Extreme Deviations From a Normative Reference Model
onlinelibrary.wiley.com/doi/full/10....
Reposted by Benedikt Sundermann
1000s of studies have been published mapping neuroanatomical changes in psychiatric disorders. Can we ever converge on robust disease phenotypes? Our latest PP led by Trang Cao in a huge collab effort investigates this question...
@nsb-lab.bsky.social
@nsb-lab.bsky.social
July 10, 2025 at 11:28 PM
1000s of studies have been published mapping neuroanatomical changes in psychiatric disorders. Can we ever converge on robust disease phenotypes? Our latest PP led by Trang Cao in a huge collab effort investigates this question...
@nsb-lab.bsky.social
@nsb-lab.bsky.social
Reposted by Benedikt Sundermann
Breath hold fMRI is great for measuring CVR... *except when your participant or patient doesn't quite perform the task the way you'd like. Let's see if we can fix that! (Spoiler, it looks like we can, using the respiratory belt data to predict or fill in missing PETCO2 data!)
New paper in Imaging Neuroscience by Rebecca G. Clements, Molly G. Bright, et al:
Quantitative mapping of cerebrovascular reactivity amplitude and delay with breath-hold BOLD fMRI when end-tidal CO2 quality is low
doi.org/10.1162/imag...
Quantitative mapping of cerebrovascular reactivity amplitude and delay with breath-hold BOLD fMRI when end-tidal CO2 quality is low
doi.org/10.1162/imag...
May 3, 2025 at 4:14 AM
Breath hold fMRI is great for measuring CVR... *except when your participant or patient doesn't quite perform the task the way you'd like. Let's see if we can fix that! (Spoiler, it looks like we can, using the respiratory belt data to predict or fill in missing PETCO2 data!)
Reposted by Benedikt Sundermann
ICYMI: Recent technological advances in functional MRI provide a range of new information about brain physiology. Collaboration between engineers and neuroscientists will help maximize these gains, writes Laura Lewis.
www.thetransmitter.org/human-neurot...
www.thetransmitter.org/human-neurot...
fMRI can do more than you think
Advances in brain imaging technology provide new and different information about the brain.
www.thetransmitter.org
June 25, 2025 at 4:19 PM
ICYMI: Recent technological advances in functional MRI provide a range of new information about brain physiology. Collaboration between engineers and neuroscientists will help maximize these gains, writes Laura Lewis.
www.thetransmitter.org/human-neurot...
www.thetransmitter.org/human-neurot...
Reposted by Benedikt Sundermann
paper: doi.org/10.1038/s415...
code: github.com/netneurolab/...
@zhenqi.bsky.social will present this work at the @ohbmofficial.bsky.social symposium: "Validating brain connectivity measures" on Friday Jun 27 3.45PM (poster 1386)
code: github.com/netneurolab/...
@zhenqi.bsky.social will present this work at the @ohbmofficial.bsky.social symposium: "Validating brain connectivity measures" on Friday Jun 27 3.45PM (poster 1386)
Benchmarking methods for mapping functional connectivity in the brain - Nature Methods
In this Analysis, Liu et al. benchmark more than 200 pairwise statistics for functional brain connectivity in tasks such as hub mapping, distance relationships, structure–function coupling and behavio...
doi.org
June 20, 2025 at 7:57 PM
paper: doi.org/10.1038/s415...
code: github.com/netneurolab/...
@zhenqi.bsky.social will present this work at the @ohbmofficial.bsky.social symposium: "Validating brain connectivity measures" on Friday Jun 27 3.45PM (poster 1386)
code: github.com/netneurolab/...
@zhenqi.bsky.social will present this work at the @ohbmofficial.bsky.social symposium: "Validating brain connectivity measures" on Friday Jun 27 3.45PM (poster 1386)
1/3 Ever wondered how the individual cortical #ASPECTS regions routinely assessed in acute #stroke imaging are related to functional #brain #networks? We have now addressed this with an atlas correspondence analysis. See our brief report preprint at doi.org/10.1101/2025...
June 24, 2025 at 7:52 PM
1/3 Ever wondered how the individual cortical #ASPECTS regions routinely assessed in acute #stroke imaging are related to functional #brain #networks? We have now addressed this with an atlas correspondence analysis. See our brief report preprint at doi.org/10.1101/2025...
Reposted by Benedikt Sundermann
Mapping cortical Alberta Stroke Program Early CT Score (ASPECTS) regions to functional brain networks https://www.medrxiv.org/content/10.1101/2025.06.20.25330017v1
June 24, 2025 at 1:12 AM
Mapping cortical Alberta Stroke Program Early CT Score (ASPECTS) regions to functional brain networks https://www.medrxiv.org/content/10.1101/2025.06.20.25330017v1
Reposted by Benedikt Sundermann
Sorry my math/stats workshop talk was a bit of a disaster as the videos didn't play :) but here it is anyway
www.youtube.com/watch?v=nCfa...
www.youtube.com/watch?v=nCfa...
Generative AI and Vision Language Models in Neuroimaging: Some Advances and Open Questions
YouTube video by Paul Thompson
www.youtube.com
June 22, 2025 at 9:43 AM
Sorry my math/stats workshop talk was a bit of a disaster as the videos didn't play :) but here it is anyway
www.youtube.com/watch?v=nCfa...
www.youtube.com/watch?v=nCfa...
Reposted by Benedikt Sundermann
On 🧠 #WorldBrainDay, let me highlight “Advancing Clinical and Neuroscientific Research Through Accessible and Optimized Protocol Design at 3T” by @srikash.bsky.social and Kâmil Uludağ, PhD (@uhn.ca, @uoft.bsky.social)
🔗 github.com/BRAIN-TO/bto...
#MRI #NeuroSky #OpenScience @mritobi.bsky.social
🔗 github.com/BRAIN-TO/bto...
#MRI #NeuroSky #OpenScience @mritobi.bsky.social
GitHub - BRAIN-TO/bto_mri_protocols_info: This is a repository of wiki, code and containers for post-processing data acquired using the BRAIN-TO imaging protocols on a Siemens Prisma 3 T
This is a repository of wiki, code and containers for post-processing data acquired using the BRAIN-TO imaging protocols on a Siemens Prisma 3 T - BRAIN-TO/bto_mri_protocols_info
github.com
June 22, 2025 at 2:43 PM
On 🧠 #WorldBrainDay, let me highlight “Advancing Clinical and Neuroscientific Research Through Accessible and Optimized Protocol Design at 3T” by @srikash.bsky.social and Kâmil Uludağ, PhD (@uhn.ca, @uoft.bsky.social)
🔗 github.com/BRAIN-TO/bto...
#MRI #NeuroSky #OpenScience @mritobi.bsky.social
🔗 github.com/BRAIN-TO/bto...
#MRI #NeuroSky #OpenScience @mritobi.bsky.social
Reposted by Benedikt Sundermann
Thanks for the great write up @ohbm-com.com! More to come #OHBM2025 @ohbmofficial.bsky.social 🧠 loom.ly/rNZb504
Keynote series Dr. Lucina Uddin - Mapping the Brain: Why Standardization Matters — OHBM Communications
The Network Correspondence Toolbox (NCT) helps neuroscientists compare brain imaging data across different atlases, addressing inconsistencies in how brain networks are labeled. Developed by Dr. Lucin...
loom.ly
June 21, 2025 at 4:00 PM
Thanks for the great write up @ohbm-com.com! More to come #OHBM2025 @ohbmofficial.bsky.social 🧠 loom.ly/rNZb504
Reposted by Benedikt Sundermann
Coming June 2025! We are excited to launch the NIH Brain Development Cohorts (NBDC) Data Hub. This new data ecosystem will host & facilitate access to data from the Adolescent Brain Cognitive Development (ABCD) Study & the HEALthy Brain and Child Development (HBCD) Study.
1/13
1/13
May 22, 2025 at 3:56 PM
Coming June 2025! We are excited to launch the NIH Brain Development Cohorts (NBDC) Data Hub. This new data ecosystem will host & facilitate access to data from the Adolescent Brain Cognitive Development (ABCD) Study & the HEALthy Brain and Child Development (HBCD) Study.
1/13
1/13
Reposted by Benedikt Sundermann
Many processes from industry are not appropriate or overkill for an academic setting, but we can and should be doing better than we currently are.
Our paper tries to give practical advice on how you can improve your scientific workflow, without being a coding guru.
www.nature.com/articles/s44...
Our paper tries to give practical advice on how you can improve your scientific workflow, without being a coding guru.
www.nature.com/articles/s44...
Ten principles for reliable, efficient, and adaptable coding in psychology and cognitive neuroscience - Communications Psychology
Programming is essential for modern research in neuroscience and psychology, but it can quickly become a source of frustration and error. This Primer introduces ten practical principles guiding resear...
www.nature.com
April 16, 2025 at 1:23 PM
Many processes from industry are not appropriate or overkill for an academic setting, but we can and should be doing better than we currently are.
Our paper tries to give practical advice on how you can improve your scientific workflow, without being a coding guru.
www.nature.com/articles/s44...
Our paper tries to give practical advice on how you can improve your scientific workflow, without being a coding guru.
www.nature.com/articles/s44...
Reposted by Benedikt Sundermann
My editorial on how journals can earn trust.
We often use journal names as proxies for quality. This is bad bc it’s not valid. But it could be. Editors could make journal name a valid signal. And we could place value on journals that show us how they do that.
journals.sagepub.com/doi/full/10....
We often use journal names as proxies for quality. This is bad bc it’s not valid. But it could be. Editors could make journal name a valid signal. And we could place value on journals that show us how they do that.
journals.sagepub.com/doi/full/10....
May 8, 2025 at 9:25 AM
My editorial on how journals can earn trust.
We often use journal names as proxies for quality. This is bad bc it’s not valid. But it could be. Editors could make journal name a valid signal. And we could place value on journals that show us how they do that.
journals.sagepub.com/doi/full/10....
We often use journal names as proxies for quality. This is bad bc it’s not valid. But it could be. Editors could make journal name a valid signal. And we could place value on journals that show us how they do that.
journals.sagepub.com/doi/full/10....
Reposted by Benedikt Sundermann
It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠
A network correspondence toolbox for quantitative evaluation of novel neuroimaging results - Nature Communications
Here, the authors present the Network Correspondence Toolbox, which enables researchers to examine and report spatial correspondence between their neuroimaging results and widely used brain atlases.
www.nature.com
March 26, 2025 at 1:54 AM
It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠
Reposted by Benedikt Sundermann
Transparency matters when reporting results in neuroimaging! arxiv.org/abs/2504.07824 This could be a landmark in setting publishing standards for interpretability/reproducibility. Stellar work by @afni-pt.bsky.social @fmri-today.bsky.social @brightmg.bsky.social @gangchen6.bsky.social et al.
April 12, 2025 at 1:13 AM
Transparency matters when reporting results in neuroimaging! arxiv.org/abs/2504.07824 This could be a landmark in setting publishing standards for interpretability/reproducibility. Stellar work by @afni-pt.bsky.social @fmri-today.bsky.social @brightmg.bsky.social @gangchen6.bsky.social et al.
Reposted by Benedikt Sundermann
The mind craves binaries: good or bad, true or false, on or off. It’s tidy. It’s comforting. But the world rarely plays along. Reality tends to unfold in gradients, not in absolutes. And so does statistical evidence. Data analysis doesn’t speak in black and white, but in shades of uncertainty.
The result of a large (42 authors!) collaboration:
"Go Figure: Transparency in neuroscience images preserves context and clarifies interpretation"
arxiv.org/abs/2504.07824
TL;DR: The FMRI world can (and should) improve results interpretation and reproducibility *today*, via transparent thresholding.
"Go Figure: Transparency in neuroscience images preserves context and clarifies interpretation"
arxiv.org/abs/2504.07824
TL;DR: The FMRI world can (and should) improve results interpretation and reproducibility *today*, via transparent thresholding.
April 12, 2025 at 8:35 PM
The mind craves binaries: good or bad, true or false, on or off. It’s tidy. It’s comforting. But the world rarely plays along. Reality tends to unfold in gradients, not in absolutes. And so does statistical evidence. Data analysis doesn’t speak in black and white, but in shades of uncertainty.
Reposted by Benedikt Sundermann
We tell our trainees to really LOOK at their data, every step of the way. This paper takes that wisdom even further, so future external readers really see our neuroimaging results in all their complex glory 👏 Thanks @afni-pt.bsky.social for spearheading this amazing team effort!
The result of a large (42 authors!) collaboration:
"Go Figure: Transparency in neuroscience images preserves context and clarifies interpretation"
arxiv.org/abs/2504.07824
TL;DR: The FMRI world can (and should) improve results interpretation and reproducibility *today*, via transparent thresholding.
"Go Figure: Transparency in neuroscience images preserves context and clarifies interpretation"
arxiv.org/abs/2504.07824
TL;DR: The FMRI world can (and should) improve results interpretation and reproducibility *today*, via transparent thresholding.
April 11, 2025 at 7:22 PM
We tell our trainees to really LOOK at their data, every step of the way. This paper takes that wisdom even further, so future external readers really see our neuroimaging results in all their complex glory 👏 Thanks @afni-pt.bsky.social for spearheading this amazing team effort!
Reposted by Benedikt Sundermann
A brief video about the topic is now available here:
www.youtube.com/watch?v=YpWl...
It covers a few (but not all!) of the examples from the "Go Figure" draft.
www.youtube.com/watch?v=YpWl...
It covers a few (but not all!) of the examples from the "Go Figure" draft.
[AFNI Academy] Go Figure: Transparency in images preserves context and clarifies interpretation
YouTube video by AFNI Bootcamp
www.youtube.com
April 11, 2025 at 12:39 PM
A brief video about the topic is now available here:
www.youtube.com/watch?v=YpWl...
It covers a few (but not all!) of the examples from the "Go Figure" draft.
www.youtube.com/watch?v=YpWl...
It covers a few (but not all!) of the examples from the "Go Figure" draft.
Reposted by Benedikt Sundermann
The result of a large (42 authors!) collaboration:
"Go Figure: Transparency in neuroscience images preserves context and clarifies interpretation"
arxiv.org/abs/2504.07824
TL;DR: The FMRI world can (and should) improve results interpretation and reproducibility *today*, via transparent thresholding.
"Go Figure: Transparency in neuroscience images preserves context and clarifies interpretation"
arxiv.org/abs/2504.07824
TL;DR: The FMRI world can (and should) improve results interpretation and reproducibility *today*, via transparent thresholding.
April 11, 2025 at 12:35 PM
The result of a large (42 authors!) collaboration:
"Go Figure: Transparency in neuroscience images preserves context and clarifies interpretation"
arxiv.org/abs/2504.07824
TL;DR: The FMRI world can (and should) improve results interpretation and reproducibility *today*, via transparent thresholding.
"Go Figure: Transparency in neuroscience images preserves context and clarifies interpretation"
arxiv.org/abs/2504.07824
TL;DR: The FMRI world can (and should) improve results interpretation and reproducibility *today*, via transparent thresholding.
Safety, technical and clinical success of the Aperio Hybrid thrombectomy device in acute ischemic stroke, a prospective post-market clinical follow-up study (HYBRID) https://www.medrxiv.org/content/10.1101/2025.04.01.25324903v1
April 7, 2025 at 5:02 AM
Reposted by Benedikt Sundermann
Some examples of what VoxelPrompt can do!
March 4, 2025 at 5:51 PM
Some examples of what VoxelPrompt can do!
Reposted by Benedikt Sundermann
Recently thought about a model which takes a delineation instruction / segmentation protocol as input and provides the respective segmentation(s). Today I read VoxelPrompt. Super interesting work by Andrew Hoopes, Victor Ion Butoi, John Guttag and @adriandalca.bsky.social.
VoxelPrompt: A Vision-Language Agent for Grounded Medical Image Analysis
We present VoxelPrompt, an agent-driven vision-language framework that tackles diverse radiological tasks through joint modeling of natural language, image volumes, and analytical metrics. VoxelPrompt...
arxiv.org
March 3, 2025 at 11:22 PM
Recently thought about a model which takes a delineation instruction / segmentation protocol as input and provides the respective segmentation(s). Today I read VoxelPrompt. Super interesting work by Andrew Hoopes, Victor Ion Butoi, John Guttag and @adriandalca.bsky.social.
Is anyone aware of a well-curated list of organisations and foundations worldwide which contribute to research infrastructure by providing databases, repositories, standards etc. who can directly receive donations via their websites? Thinking of @cos.io as an example…. Please continue!
March 2, 2025 at 10:13 AM
Is anyone aware of a well-curated list of organisations and foundations worldwide which contribute to research infrastructure by providing databases, repositories, standards etc. who can directly receive donations via their websites? Thinking of @cos.io as an example…. Please continue!