Auclair Lab
@auclairlab.bsky.social
We explore many fields of chemistry and biology (many of them concerning enzymes).
Located at McGill University, Montreal.
Student-ran account: posts not by Dr. Auclair unless indicated.
RP/follow ≠ endorsement.
https://www.auclair-group.mcgill.ca
Located at McGill University, Montreal.
Student-ran account: posts not by Dr. Auclair unless indicated.
RP/follow ≠ endorsement.
https://www.auclair-group.mcgill.ca
Prof. Auclair presented at the McGill Interdisciplinary Initiative in Infection and Immunity (MI4) annual symposium last week!
November 26, 2025 at 2:52 PM
Prof. Auclair presented at the McGill Interdisciplinary Initiative in Infection and Immunity (MI4) annual symposium last week!
Come find us at @concordia.ca Loyola campus for CBGRC this Friday!
November 17, 2025 at 3:16 PM
Come find us at @concordia.ca Loyola campus for CBGRC this Friday!
NEW PREPRINT:
An extensive structure-activity relationship investigation of pantetheinamides and their ability to inhibit Salmonella typhimurium.
We investigate the mechanisms of action of these compounds and their use with in vivo mouse models.
doi.org/10.1101/2025...
An extensive structure-activity relationship investigation of pantetheinamides and their ability to inhibit Salmonella typhimurium.
We investigate the mechanisms of action of these compounds and their use with in vivo mouse models.
doi.org/10.1101/2025...
October 30, 2025 at 7:54 PM
NEW PREPRINT:
An extensive structure-activity relationship investigation of pantetheinamides and their ability to inhibit Salmonella typhimurium.
We investigate the mechanisms of action of these compounds and their use with in vivo mouse models.
doi.org/10.1101/2025...
An extensive structure-activity relationship investigation of pantetheinamides and their ability to inhibit Salmonella typhimurium.
We investigate the mechanisms of action of these compounds and their use with in vivo mouse models.
doi.org/10.1101/2025...
Good Wordle yesterday.
October 8, 2025 at 3:38 PM
Good Wordle yesterday.
Doing a little setup for our new baby 👀
September 4, 2025 at 1:23 PM
Doing a little setup for our new baby 👀
The Auclair lab went tree trekking recently! Super fun teambuilding exercise.
August 28, 2025 at 2:34 PM
The Auclair lab went tree trekking recently! Super fun teambuilding exercise.
Very happy to meet 2020 Nobel Prize laureate @e-charpentier.bsky.social at @ircm.bsky.social!
August 20, 2025 at 2:48 PM
Very happy to meet 2020 Nobel Prize laureate @e-charpentier.bsky.social at @ircm.bsky.social!
‼️NEW PAPER ALERT
In Antimicrobial Agents and Chemotherapy, we replace an enzyme-vulnerable amide bond with a thiazole to produce potent antiplasmodial and antimalarial pantothenamide mimics. A collaboration between the Auclair lab @mcgill.ca and the Saliba lab at ANU.
doi.org/10.1128/aac....
🧵
In Antimicrobial Agents and Chemotherapy, we replace an enzyme-vulnerable amide bond with a thiazole to produce potent antiplasmodial and antimalarial pantothenamide mimics. A collaboration between the Auclair lab @mcgill.ca and the Saliba lab at ANU.
doi.org/10.1128/aac....
🧵
August 13, 2025 at 5:10 PM
‼️NEW PAPER ALERT
In Antimicrobial Agents and Chemotherapy, we replace an enzyme-vulnerable amide bond with a thiazole to produce potent antiplasmodial and antimalarial pantothenamide mimics. A collaboration between the Auclair lab @mcgill.ca and the Saliba lab at ANU.
doi.org/10.1128/aac....
🧵
In Antimicrobial Agents and Chemotherapy, we replace an enzyme-vulnerable amide bond with a thiazole to produce potent antiplasmodial and antimalarial pantothenamide mimics. A collaboration between the Auclair lab @mcgill.ca and the Saliba lab at ANU.
doi.org/10.1128/aac....
🧵
Throwback: in 2012, our lab investigated prodrugs - activated by the CoA pathway - to resensitize resistant bacteria to aminoglycoside antibiotics. #chemsky
doi.org/10.1021/cb20...
doi.org/10.1021/cb20...
July 3, 2025 at 1:11 AM
Throwback: in 2012, our lab investigated prodrugs - activated by the CoA pathway - to resensitize resistant bacteria to aminoglycoside antibiotics. #chemsky
doi.org/10.1021/cb20...
doi.org/10.1021/cb20...
🚨NEW PREPRINT ALERT:
In this paper, Jacob and Suzana from the Auclair lab investigate how Salmonella Typhimurium adapts to growing on itaconate, with detailed metabolic and genomic studies.
Many thanks to our collaborators at McGill and Concordia! (Details below) #chemsky
doi.org/10.1101/2025...
In this paper, Jacob and Suzana from the Auclair lab investigate how Salmonella Typhimurium adapts to growing on itaconate, with detailed metabolic and genomic studies.
Many thanks to our collaborators at McGill and Concordia! (Details below) #chemsky
doi.org/10.1101/2025...
June 21, 2025 at 11:57 AM
🚨NEW PREPRINT ALERT:
In this paper, Jacob and Suzana from the Auclair lab investigate how Salmonella Typhimurium adapts to growing on itaconate, with detailed metabolic and genomic studies.
Many thanks to our collaborators at McGill and Concordia! (Details below) #chemsky
doi.org/10.1101/2025...
In this paper, Jacob and Suzana from the Auclair lab investigate how Salmonella Typhimurium adapts to growing on itaconate, with detailed metabolic and genomic studies.
Many thanks to our collaborators at McGill and Concordia! (Details below) #chemsky
doi.org/10.1101/2025...
Our very own Tarasha is a TV star now!
She appeared on CBC News Montreal as part of McGill's Chemistry Outreach program, demonstrating the wonders of science to kids (and a few adults.)
[We only have a video of the broadcast, but it's still worth a watch...!]
She appeared on CBC News Montreal as part of McGill's Chemistry Outreach program, demonstrating the wonders of science to kids (and a few adults.)
[We only have a video of the broadcast, but it's still worth a watch...!]
May 15, 2025 at 4:31 PM
Our very own Tarasha is a TV star now!
She appeared on CBC News Montreal as part of McGill's Chemistry Outreach program, demonstrating the wonders of science to kids (and a few adults.)
[We only have a video of the broadcast, but it's still worth a watch...!]
She appeared on CBC News Montreal as part of McGill's Chemistry Outreach program, demonstrating the wonders of science to kids (and a few adults.)
[We only have a video of the broadcast, but it's still worth a watch...!]
The team took advantage of the Montreal heat wave with a picnic!
May 15, 2025 at 3:40 PM
The team took advantage of the Montreal heat wave with a picnic!
