Ashwin Sudarshan
@ashsudarshan.bsky.social
Env. Eng. PhD student at Georgia Tech. Studying microbes in drinking water one genome at a time💧💧🦠🦠
🤔🤔
I post blogs:
https://ashsudarshan.substack.com
🤔🤔
I post blogs:
https://ashsudarshan.substack.com
My second paper is out as a pre-print. Check it out!
Gene-centric analysis of Raskinella chloraquaticus reveals a functionally conserved taxonomic group in global drinking water distribution systems https://www.biorxiv.org/content/10.1101/2025.11.10.687676v1
November 14, 2025 at 8:24 PM
My second paper is out as a pre-print. Check it out!
Reposted by Ashwin Sudarshan
💥 Excited to introduce Bacformer 🦠 - the first foundation model for bacterial genomics. Bacformer represents genomes as sequences of ordered proteins, learning the “grammar” of how genes are arranged, interact and evolve.
Preprint 📝: biorxiv.org/content/10.1...
🧵 1/n
Preprint 📝: biorxiv.org/content/10.1...
🧵 1/n
July 21, 2025 at 9:56 AM
💥 Excited to introduce Bacformer 🦠 - the first foundation model for bacterial genomics. Bacformer represents genomes as sequences of ordered proteins, learning the “grammar” of how genes are arranged, interact and evolve.
Preprint 📝: biorxiv.org/content/10.1...
🧵 1/n
Preprint 📝: biorxiv.org/content/10.1...
🧵 1/n
I have heard Julie rave about this project for a while. Super excited about this campaign!! Please fund this!!🤩🤩🤩🤩😃😃😃😃
Please support my students kickstarter to finish an educational wastewater video game we started building!
I taught an interdisciplinary capstone class video game where programmers, artists, sound designers, and education students could work together!
www.kickstarter.com/projects/que...
I taught an interdisciplinary capstone class video game where programmers, artists, sound designers, and education students could work together!
www.kickstarter.com/projects/que...
What the Floc: Educational Wastewater Video Game
Educational video game where players operate a wastewater treatment plant to protect the city and environment from pollution!
www.kickstarter.com
May 13, 2025 at 2:23 AM
I have heard Julie rave about this project for a while. Super excited about this campaign!! Please fund this!!🤩🤩🤩🤩😃😃😃😃
Reposted by Ashwin Sudarshan
Check out this list of awesome #virome tools and be sure to add yours!
github.com/shandley/awe...
#phagesky #microsky
github.com/shandley/awe...
#phagesky #microsky
GitHub - shandley/awesome-virome: A listing of software, tools and databases useful for virome analysis
A listing of software, tools and databases useful for virome analysis - shandley/awesome-virome
github.com
March 12, 2025 at 8:46 PM
Check out this list of awesome #virome tools and be sure to add yours!
github.com/shandley/awe...
#phagesky #microsky
github.com/shandley/awe...
#phagesky #microsky
Reposted by Ashwin Sudarshan
If you have been using #anvio to analyze your microbial pangenomes, we have a new program for you to calculate rarefaction curves or Heaps' Law fit for your gene clusters:
anvio.org/help/main/pr...
Sorry it took this long :/ But at least t will run on any existing anvi'o pangenome :)
anvio.org/help/main/pr...
Sorry it took this long :/ But at least t will run on any existing anvi'o pangenome :)
March 2, 2025 at 3:13 PM
If you have been using #anvio to analyze your microbial pangenomes, we have a new program for you to calculate rarefaction curves or Heaps' Law fit for your gene clusters:
anvio.org/help/main/pr...
Sorry it took this long :/ But at least t will run on any existing anvi'o pangenome :)
anvio.org/help/main/pr...
Sorry it took this long :/ But at least t will run on any existing anvi'o pangenome :)
Reposted by Ashwin Sudarshan
Looks interesting, plasmid assembly from multiple metagenomes
"On synthetic benchmark datasets, PlasMAAG reconstructed 50-121% more near-complete plasmids than competing methods and improved the Matthews Correlation Coefficient of geNomad contig classif. by 28-106%
www.biorxiv.org/content/10.1...
"On synthetic benchmark datasets, PlasMAAG reconstructed 50-121% more near-complete plasmids than competing methods and improved the Matthews Correlation Coefficient of geNomad contig classif. by 28-106%
www.biorxiv.org/content/10.1...
March 2, 2025 at 7:01 AM
Looks interesting, plasmid assembly from multiple metagenomes
"On synthetic benchmark datasets, PlasMAAG reconstructed 50-121% more near-complete plasmids than competing methods and improved the Matthews Correlation Coefficient of geNomad contig classif. by 28-106%
www.biorxiv.org/content/10.1...
"On synthetic benchmark datasets, PlasMAAG reconstructed 50-121% more near-complete plasmids than competing methods and improved the Matthews Correlation Coefficient of geNomad contig classif. by 28-106%
www.biorxiv.org/content/10.1...
Reposted by Ashwin Sudarshan
Was a pleasure writing this with @whiteleylab, excited to share it with the biofilm community!
rdcu.be/dQf4Z
rdcu.be/dQf4Z
Towards improved biofilm models
Nature Reviews Microbiology - In this Perspective, Rumbaugh and Whiteley explore the advantages and limitations of current medical biofilm models and outline a framework for quantitatively...
rdcu.be
August 7, 2024 at 11:34 PM
Was a pleasure writing this with @whiteleylab, excited to share it with the biofilm community!
rdcu.be/dQf4Z
rdcu.be/dQf4Z
Reposted by Ashwin Sudarshan
Eight years later, I revisit the tree of life. “Future trees may need to distinguish not only between cultured and uncultured lineages, but between extant and extinct”
rdcu.be/dPNpB
rdcu.be/dPNpB
The ever-changing tree of life
Nature Microbiology - The tree of life is a galvanizing image, anchoring biological diversity within a common framework. From a new view in 2016, the tree has continued to grow, and with it, our...
rdcu.be
August 2, 2024 at 8:40 PM
Eight years later, I revisit the tree of life. “Future trees may need to distinguish not only between cultured and uncultured lineages, but between extant and extinct”
rdcu.be/dPNpB
rdcu.be/dPNpB
Are there any specific Fourth of July traditions people follow?? Super curious how this holiday is celebrated and what people do!!🥳🥳😊😊
July 4, 2024 at 5:36 PM
Are there any specific Fourth of July traditions people follow?? Super curious how this holiday is celebrated and what people do!!🥳🥳😊😊
Reposted by Ashwin Sudarshan
Interesting approach:
Strain tracking in complex microbiomes using synteny analysis reveals per-species modes of evolution
www.nature.com/articles/s41...
Strain tracking in complex microbiomes using synteny analysis reveals per-species modes of evolution
www.nature.com/articles/s41...
Strain tracking in complex microbiomes using synteny analysis reveals per-species modes of evolution - Nature Biotechnology
The evolution of microbial strains is revealed by analyzing structural variation.
www.nature.com
June 21, 2024 at 1:33 PM
Interesting approach:
Strain tracking in complex microbiomes using synteny analysis reveals per-species modes of evolution
www.nature.com/articles/s41...
Strain tracking in complex microbiomes using synteny analysis reveals per-species modes of evolution
www.nature.com/articles/s41...
Poster up #ASMicrobe based on our latest preprint! Happy to chat about this work in case anyone is interested!
June 14, 2024 at 1:41 PM
Poster up #ASMicrobe based on our latest preprint! Happy to chat about this work in case anyone is interested!
It always blows my mind how Mexican and Indian cuisine have a lot of similarities!!🤯🤯🤯
Tajin chilis smell a lot like the kind of chilis my mom uses in South India (We call it “Gundu Milagai” locally and it translates to fat chili because these are short and round in shape).
Tajin chilis smell a lot like the kind of chilis my mom uses in South India (We call it “Gundu Milagai” locally and it translates to fat chili because these are short and round in shape).
June 10, 2024 at 2:22 AM
It always blows my mind how Mexican and Indian cuisine have a lot of similarities!!🤯🤯🤯
Tajin chilis smell a lot like the kind of chilis my mom uses in South India (We call it “Gundu Milagai” locally and it translates to fat chili because these are short and round in shape).
Tajin chilis smell a lot like the kind of chilis my mom uses in South India (We call it “Gundu Milagai” locally and it translates to fat chili because these are short and round in shape).
Reposted by Ashwin Sudarshan
Very excited for this new @biorxivpreprint.bsky.social led by @ashsudarshan.bsky.social! "New drinking water genome catalog identifies a globally distributed bacterial genus adapted to disinfected drinking water systems." Check it out.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
New drinking water genome catalog identifies a globally distributed bacterial genus adapted to disinfected drinking water systems.
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
May 23, 2024 at 12:41 PM
Very excited for this new @biorxivpreprint.bsky.social led by @ashsudarshan.bsky.social! "New drinking water genome catalog identifies a globally distributed bacterial genus adapted to disinfected drinking water systems." Check it out.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Anybody has a good template to make a resume? Been meaning to update and improve my resume and would love some templates to work with. Thanks!
March 23, 2024 at 7:32 PM
Anybody has a good template to make a resume? Been meaning to update and improve my resume and would love some templates to work with. Thanks!
Reposted by Ashwin Sudarshan
Reposting this message: I am looking to hire a lab manager/research technician for our laboratory. Please help us spread the word. If you know of any motivated candidates, please encourage them to contact me. Microbiology lab experience would be preferred. Looking for at least a 1.5 year commitment.
November 28, 2023 at 8:18 PM
Reposting this message: I am looking to hire a lab manager/research technician for our laboratory. Please help us spread the word. If you know of any motivated candidates, please encourage them to contact me. Microbiology lab experience would be preferred. Looking for at least a 1.5 year commitment.
My mom was very excited to watch India in the ICC World Cup finals:
Me: Do you know that India has never beat Australia in a WC Finals.
Mom: Yeah :(
Me: Well… There’s a first time for everything…
Mom: 😃😃😃
Famous last words😭😭😭
Me: Do you know that India has never beat Australia in a WC Finals.
Mom: Yeah :(
Me: Well… There’s a first time for everything…
Mom: 😃😃😃
Famous last words😭😭😭
November 19, 2023 at 6:29 PM
My mom was very excited to watch India in the ICC World Cup finals:
Me: Do you know that India has never beat Australia in a WC Finals.
Mom: Yeah :(
Me: Well… There’s a first time for everything…
Mom: 😃😃😃
Famous last words😭😭😭
Me: Do you know that India has never beat Australia in a WC Finals.
Mom: Yeah :(
Me: Well… There’s a first time for everything…
Mom: 😃😃😃
Famous last words😭😭😭
Reposted by Ashwin Sudarshan
Looking to recruit 3 grad researchers. (1) Drinking water micro-ecology, (2) Nitrogen micro (specifically comammox), and (3) Algal micro + imaging. as Spring 2024 & late as Fall 2024. if you know someone creative + motivated + interested in these topics - would appreciate u sharing this with them.
November 14, 2023 at 10:44 PM
Looking to recruit 3 grad researchers. (1) Drinking water micro-ecology, (2) Nitrogen micro (specifically comammox), and (3) Algal micro + imaging. as Spring 2024 & late as Fall 2024. if you know someone creative + motivated + interested in these topics - would appreciate u sharing this with them.
Atlanta is so warm for this time of the year that trees are confused about shedding their leaves?😓😓
November 9, 2023 at 2:57 PM
Atlanta is so warm for this time of the year that trees are confused about shedding their leaves?😓😓
Tried Tteokbokki for the first time today!
Sweet, Spicy chewy goodness🤤🤤
Sweet, Spicy chewy goodness🤤🤤
November 5, 2023 at 1:03 AM
Tried Tteokbokki for the first time today!
Sweet, Spicy chewy goodness🤤🤤
Sweet, Spicy chewy goodness🤤🤤
Reposted by Ashwin Sudarshan
wonderful joint research group pumpkin carving halloween party last night with @methanojen.bsky.social’s and katy graham’s groups.
October 22, 2023 at 11:58 AM
wonderful joint research group pumpkin carving halloween party last night with @methanojen.bsky.social’s and katy graham’s groups.
Me: What a week huh??😥😥😓😓
Later realizes it is only Wednesday😓😓😓
Later realizes it is only Wednesday😓😓😓
October 19, 2023 at 1:05 AM
Me: What a week huh??😥😥😓😓
Later realizes it is only Wednesday😓😓😓
Later realizes it is only Wednesday😓😓😓
Saw this Ad pitting Kit Kat and Reese’s for Halloween. This isn’t a fair fight…
It is obviously Reese’s🤤🤤🤤
It is obviously Reese’s🤤🤤🤤
October 13, 2023 at 1:12 AM
Saw this Ad pitting Kit Kat and Reese’s for Halloween. This isn’t a fair fight…
It is obviously Reese’s🤤🤤🤤
It is obviously Reese’s🤤🤤🤤
Reposted by Ashwin Sudarshan
Unraveling the functional dark matter through global metagenomics www.nature.com/articles/s41... #jcampubs
Unraveling the functional dark matter through global metagenomics - Nature
A computational approach to generate reference-free protein families from the sequence space in metagenomes reveals an enormously diverse functional space.
www.nature.com
October 12, 2023 at 1:40 PM
Unraveling the functional dark matter through global metagenomics www.nature.com/articles/s41... #jcampubs
Are there any standard softwares people use to generate animations for slides? Other than biorender..
Especially microbial animations for papers and presentations.
Especially microbial animations for papers and presentations.
October 5, 2023 at 9:53 PM
Are there any standard softwares people use to generate animations for slides? Other than biorender..
Especially microbial animations for papers and presentations.
Especially microbial animations for papers and presentations.