Alex Sampson
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asampson96.bsky.social
Alex Sampson
@asampson96.bsky.social
DPhil student at Pandemic Sciences Institute - interested in Immunology, Virology and Vaccines, previously worked as a mixed vet in the Outer Hebrides 🐕 🦠
Reposted by Alex Sampson
1. #Ebola: There is a new outbreak, Ebola Sudan, in Uganda. The current index case (who probably isn't the index case) died yesterday. The person was a nurse who sought care in multiple hospitals before dying. Ebola was only determined post mortem.
Possibility of additional cases high.
January 30, 2025 at 1:43 PM
Reposted by Alex Sampson
🚨 New preprint alert 🚨

We searched for the presence of coronaviruses in >200 bat individuals across Spain 🦠🦇. We recovered 6 complete coronavirus genomes, including 3 novel species. One of them could use bat and human ACE2 for entry.

www.biorxiv.org/content/10.1...
Identification and characterization of novel bat coronaviruses in Spain
The zoonotic transmission of bat coronaviruses poses a threat to human health. However, the diversity of bat-borne coronaviruses remains poorly characterized in many geographical areas. Here, we recov...
www.biorxiv.org
January 9, 2025 at 9:11 AM
Reposted by Alex Sampson
Really proud to share our preprint describing early adaptation of H5N1 to US dairy cattle, and showing how these mutations enhance the ability of the virus to infect other mammals, such as pigs and humans.

With @influenzal.bsky.social @vidhid.bsky.social @drclairesmith.bsky.social and many more!
Polymerase mutations underlie adaptation of H5N1 influenza virus to dairy cattle and other mammals.
In early 2024, an unprecedented outbreak of H5N1 high pathogenicity avian influenza was detected in dairy cattle in the USA. The epidemic remains uncontrolled, with spillbacks into poultry, wild birds...
www.biorxiv.org
January 7, 2025 at 7:59 AM
Reposted by Alex Sampson
I’m pleased to share that we FINALLY submitted our latest manuscript on SARS-CoV-2 cryptic lineages and what they tell us about the origins of COVID-19.
This was a ton of work.
medrxiv.org/cgi/content/...
1/
Detecting SARS-CoV-2 Cryptic Lineages using Publicly Available Whole Genome Wastewater Sequencing Data
Beginning in early 2021, unique and highly divergent lineages of SARS-CoV-2 were sporadically found in wastewater sewersheds using a sequencing strategy focused on the most mutagenic region of SARS-Co...
medrxiv.org
December 28, 2024 at 11:17 AM