@arvoiovs.bsky.social
Wei Liu et al. from Tianjin Medical University Eye Hospital explore the association between chronic kidney disease and glaucoma using data from the Lifelines Cohort Study and UK Biobank.
doi.org/10.1167/iovs.66.15.17
doi.org/10.1167/iovs.66.15.17
December 3, 2025 at 7:57 PM
Wei Liu et al. from Tianjin Medical University Eye Hospital explore the association between chronic kidney disease and glaucoma using data from the Lifelines Cohort Study and UK Biobank.
doi.org/10.1167/iovs.66.15.17
doi.org/10.1167/iovs.66.15.17
Wenru Su et al. from Shanghai Jiao Tong University School of Medicine investigate the effect of dipyridamole on experimental autoimmune uveitis.
doi.org/10.1167/iovs.66.15.16
doi.org/10.1167/iovs.66.15.16
December 3, 2025 at 7:56 PM
Wenru Su et al. from Shanghai Jiao Tong University School of Medicine investigate the effect of dipyridamole on experimental autoimmune uveitis.
doi.org/10.1167/iovs.66.15.16
doi.org/10.1167/iovs.66.15.16
Chi-Chang Shieh et al. from National Cheng Kung University Hospital report that U1 RNA detected by toll-like receptor 3 plays a role in the pathogenesis of pterygium.
doi.org/10.1167/iovs.66.15.15
doi.org/10.1167/iovs.66.15.15
December 3, 2025 at 7:56 PM
Chi-Chang Shieh et al. from National Cheng Kung University Hospital report that U1 RNA detected by toll-like receptor 3 plays a role in the pathogenesis of pterygium.
doi.org/10.1167/iovs.66.15.15
doi.org/10.1167/iovs.66.15.15
Rong Lu, Junjie Tang et al. from Zhongshan Ophthalmic Center find that targeting MCM6 enhances melphalan chemosensitivity in retinoblastoma by modulating DNA damage response.
doi.org/10.1167/iovs.66.15.14
doi.org/10.1167/iovs.66.15.14
December 3, 2025 at 7:55 PM
Rong Lu, Junjie Tang et al. from Zhongshan Ophthalmic Center find that targeting MCM6 enhances melphalan chemosensitivity in retinoblastoma by modulating DNA damage response.
doi.org/10.1167/iovs.66.15.14
doi.org/10.1167/iovs.66.15.14
Xi Wang et al. from Sichuan University show that regaining visual acuity does not restore motion extrapolation deficits in amblyopia.
doi.org/10.1167/iovs.66.15.13
doi.org/10.1167/iovs.66.15.13
December 2, 2025 at 7:24 PM
Xi Wang et al. from Sichuan University show that regaining visual acuity does not restore motion extrapolation deficits in amblyopia.
doi.org/10.1167/iovs.66.15.13
doi.org/10.1167/iovs.66.15.13
Swathi Kaliki et al from the L. V. Prasad Eye Institute explore and compare the serum metabolic alterations in treatment-naïve active retinoblastoma (RB) and regressed RB post-treatment.
doi.org/10.1167/iovs.66.15.12
doi.org/10.1167/iovs.66.15.12
December 2, 2025 at 7:24 PM
Swathi Kaliki et al from the L. V. Prasad Eye Institute explore and compare the serum metabolic alterations in treatment-naïve active retinoblastoma (RB) and regressed RB post-treatment.
doi.org/10.1167/iovs.66.15.12
doi.org/10.1167/iovs.66.15.12
Asma M. Aman et al. from The University of Queensland explore the shared genetic architectures between primary open-angle glaucoma and visual pathway regions in the brain.
doi.org/10.1167/iovs.66.15.11
doi.org/10.1167/iovs.66.15.11
December 2, 2025 at 7:23 PM
Asma M. Aman et al. from The University of Queensland explore the shared genetic architectures between primary open-angle glaucoma and visual pathway regions in the brain.
doi.org/10.1167/iovs.66.15.11
doi.org/10.1167/iovs.66.15.11
Aysegül Tura et al. from the University of Lübeck investigate the missegregation of chromosome 3 and generation of monosomy 3 in the proliferating uveal melanoma cells under hyperglycemia.
doi.org/10.1167/iovs.66.15.10
doi.org/10.1167/iovs.66.15.10
December 2, 2025 at 7:23 PM
Aysegül Tura et al. from the University of Lübeck investigate the missegregation of chromosome 3 and generation of monosomy 3 in the proliferating uveal melanoma cells under hyperglycemia.
doi.org/10.1167/iovs.66.15.10
doi.org/10.1167/iovs.66.15.10
Orson L. Moritz from the University of British Columbia describe a survey of opsin localization, glycosylation, and light/chromophore influence on degeneration in 26 rhodopsin-associated RP models.
doi.org/10.1167/iovs.66.15.9
doi.org/10.1167/iovs.66.15.9
December 2, 2025 at 7:23 PM
Orson L. Moritz from the University of British Columbia describe a survey of opsin localization, glycosylation, and light/chromophore influence on degeneration in 26 rhodopsin-associated RP models.
doi.org/10.1167/iovs.66.15.9
doi.org/10.1167/iovs.66.15.9
Shrikant R. Bharadwaj et al. from the L. V. Prasad Eye Institute determine the impact of induced optical blur on a 3D task that probes complex visuomotor performance capabilities of humans.
doi.org/10.1167/iovs.66.15.8
doi.org/10.1167/iovs.66.15.8
December 2, 2025 at 7:22 PM
Shrikant R. Bharadwaj et al. from the L. V. Prasad Eye Institute determine the impact of induced optical blur on a 3D task that probes complex visuomotor performance capabilities of humans.
doi.org/10.1167/iovs.66.15.8
doi.org/10.1167/iovs.66.15.8
Xinping Yu et al. from Zhongshan Ophthalmic Center present a randomized clinical study investigating the effects of individualized adaptive perceptual learning on control scores, stereopsis, and ocular alignment in children with intermittent exotropia. doi.org/10.1167/iovs.66.15.6
December 2, 2025 at 7:21 PM
Xinping Yu et al. from Zhongshan Ophthalmic Center present a randomized clinical study investigating the effects of individualized adaptive perceptual learning on control scores, stereopsis, and ocular alignment in children with intermittent exotropia. doi.org/10.1167/iovs.66.15.6
New article in the Myopia issue bit.ly/4arV0Pr by Elise Harb et al UC Berkeley reviews how characteristics of light such as intensity, spectrum & photoperiod may affect refractive development via image & non image forming pathways.
doi.org/10.1167/iovs.66.15.5
doi.org/10.1167/iovs.66.15.5
December 2, 2025 at 7:20 PM
New article in the Myopia issue bit.ly/4arV0Pr by Elise Harb et al UC Berkeley reviews how characteristics of light such as intensity, spectrum & photoperiod may affect refractive development via image & non image forming pathways.
doi.org/10.1167/iovs.66.15.5
doi.org/10.1167/iovs.66.15.5
Henri Leinonen et al. from the University of Eastern Finland investigate presynaptic changes in mouse rod photoreceptors during early retinitis pigmentosa.
doi.org/10.1167/iovs.66.15.4
doi.org/10.1167/iovs.66.15.4
December 1, 2025 at 4:54 PM
Henri Leinonen et al. from the University of Eastern Finland investigate presynaptic changes in mouse rod photoreceptors during early retinitis pigmentosa.
doi.org/10.1167/iovs.66.15.4
doi.org/10.1167/iovs.66.15.4
Amani A. Fawzi et al. from Department Northwestern University find that macular microaneurysms are associated with chronic kidney disease and deep capillary plexus ischemia in referable diabetic retinopathy.
doi.org/10.1167/iovs.66.15.3
doi.org/10.1167/iovs.66.15.3
December 1, 2025 at 4:54 PM
Amani A. Fawzi et al. from Department Northwestern University find that macular microaneurysms are associated with chronic kidney disease and deep capillary plexus ischemia in referable diabetic retinopathy.
doi.org/10.1167/iovs.66.15.3
doi.org/10.1167/iovs.66.15.3
homas H. Dohlman et al. from Schepens Eye Research Institute evaluate the immunoregulatory effect of corneal myofibroblasts on effector T cells derived from allogeneic corneal transplant recipient mice.
doi.org/10.1167/iovs.66.15.2
doi.org/10.1167/iovs.66.15.2
December 1, 2025 at 4:53 PM
homas H. Dohlman et al. from Schepens Eye Research Institute evaluate the immunoregulatory effect of corneal myofibroblasts on effector T cells derived from allogeneic corneal transplant recipient mice.
doi.org/10.1167/iovs.66.15.2
doi.org/10.1167/iovs.66.15.2
Zi-Bing Jin et al from the Tongren Eye Center find that retinal pigment epithelium extracellular vesicles induce microglia polarization in MERTK-associated retinal degeneration.
doi.org/10.1167/iovs.66.15.1
doi.org/10.1167/iovs.66.15.1
December 1, 2025 at 4:53 PM
Zi-Bing Jin et al from the Tongren Eye Center find that retinal pigment epithelium extracellular vesicles induce microglia polarization in MERTK-associated retinal degeneration.
doi.org/10.1167/iovs.66.15.1
doi.org/10.1167/iovs.66.15.1
Yifu Ding, Andrew Metha & Phillip Bedggood from the University of Melbourne characterize red blood cell (RBC) distribution and associated changes in cell size at capillary junctions in the human neural retina.
doi.org/10.1167/iovs.66.14.65
doi.org/10.1167/iovs.66.14.65
November 26, 2025 at 4:24 PM
Yifu Ding, Andrew Metha & Phillip Bedggood from the University of Melbourne characterize red blood cell (RBC) distribution and associated changes in cell size at capillary junctions in the human neural retina.
doi.org/10.1167/iovs.66.14.65
doi.org/10.1167/iovs.66.14.65
Srinivas R. Sadda et al from Doheny Eye Institute compare choriocapillaris flow deficit percentages between eyes with extensive macular atrophy with pseudodrusen-like appearance and geographic atrophy secondary to age-related macular degeneration.
doi.org/10.1167/iovs.66.14.64
doi.org/10.1167/iovs.66.14.64
November 26, 2025 at 4:23 PM
Srinivas R. Sadda et al from Doheny Eye Institute compare choriocapillaris flow deficit percentages between eyes with extensive macular atrophy with pseudodrusen-like appearance and geographic atrophy secondary to age-related macular degeneration.
doi.org/10.1167/iovs.66.14.64
doi.org/10.1167/iovs.66.14.64
Boris Peñaloza & MiYoung Kwon from Northeastern University characterize age-related changes in binocular summation for contrast sensitivity (CS) and high-contrast visual acuity (VA) across adulthood and evaluate the mechanisms underlying this integration.
doi.org/10.1167/iovs.66.14.63
doi.org/10.1167/iovs.66.14.63
November 26, 2025 at 4:23 PM
Boris Peñaloza & MiYoung Kwon from Northeastern University characterize age-related changes in binocular summation for contrast sensitivity (CS) and high-contrast visual acuity (VA) across adulthood and evaluate the mechanisms underlying this integration.
doi.org/10.1167/iovs.66.14.63
doi.org/10.1167/iovs.66.14.63
Yuanbo Liang et al. from Wenzhou Medical University develop a novel rabbit model of angle-closure glaucoma via ciliary block and elevated trans-lens pressure difference.
doi.org/10.1167/iovs.66.14.60
doi.org/10.1167/iovs.66.14.60
November 24, 2025 at 3:46 PM
Yuanbo Liang et al. from Wenzhou Medical University develop a novel rabbit model of angle-closure glaucoma via ciliary block and elevated trans-lens pressure difference.
doi.org/10.1167/iovs.66.14.60
doi.org/10.1167/iovs.66.14.60
Rajiv R. Mohan et al. from the University of Missouri find that epigenetic reprogramming via sodium butyrate induces corneal myofibroblast dedifferentiation in vitro and inhibits fibrosis in vivo.
doi.org/10.1167/iovs.66.14.59
doi.org/10.1167/iovs.66.14.59
November 24, 2025 at 3:46 PM
Rajiv R. Mohan et al. from the University of Missouri find that epigenetic reprogramming via sodium butyrate induces corneal myofibroblast dedifferentiation in vitro and inhibits fibrosis in vivo.
doi.org/10.1167/iovs.66.14.59
doi.org/10.1167/iovs.66.14.59
Xuemin Jin et al. from The First Affiliated Hospital of Zhengzhou University establish preclinical safety data to advance mitochondrial targeted AAV-delivered human ND4 (MTSAAV/hND4) for treatment of Leber Hereditary Optic Neuropathy (LHON).
doi.org/10.1167/iovs.66.14.58
doi.org/10.1167/iovs.66.14.58
November 24, 2025 at 3:45 PM
Xuemin Jin et al. from The First Affiliated Hospital of Zhengzhou University establish preclinical safety data to advance mitochondrial targeted AAV-delivered human ND4 (MTSAAV/hND4) for treatment of Leber Hereditary Optic Neuropathy (LHON).
doi.org/10.1167/iovs.66.14.58
doi.org/10.1167/iovs.66.14.58
David Križaj et al. from the University of Utah School of Medicine find that mechano- and glucocorticoid-sensitive TREK-1 channels regulate conventional outflow and intraocular pressure.
doi.org/10.1167/iovs.66.14.57
doi.org/10.1167/iovs.66.14.57
November 21, 2025 at 5:27 PM
David Križaj et al. from the University of Utah School of Medicine find that mechano- and glucocorticoid-sensitive TREK-1 channels regulate conventional outflow and intraocular pressure.
doi.org/10.1167/iovs.66.14.57
doi.org/10.1167/iovs.66.14.57
New article in the Nystagmus issue bit.ly/48sUcZd by Matt J. Dunnet al. from Cardiff University find that the human fovea Is relatively horizontally elongated in infantile nystagmus.
doi.org/10.1167/iovs.66.14.56
doi.org/10.1167/iovs.66.14.56
November 21, 2025 at 5:26 PM
New article in the Nystagmus issue bit.ly/48sUcZd by Matt J. Dunnet al. from Cardiff University find that the human fovea Is relatively horizontally elongated in infantile nystagmus.
doi.org/10.1167/iovs.66.14.56
doi.org/10.1167/iovs.66.14.56
Giancarlo Iarossi et al. from Bambino Gesù Children's Hospital evaluate the inner retinal changes in patients with ABCA4-related retinal dystrophy (ABCA4-RD), and correlate these changes with the photopic negative response (PhNR).
doi.org/10.1167/iovs.66.14.55
doi.org/10.1167/iovs.66.14.55
November 21, 2025 at 5:24 PM
Giancarlo Iarossi et al. from Bambino Gesù Children's Hospital evaluate the inner retinal changes in patients with ABCA4-related retinal dystrophy (ABCA4-RD), and correlate these changes with the photopic negative response (PhNR).
doi.org/10.1167/iovs.66.14.55
doi.org/10.1167/iovs.66.14.55