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Jiaxu Hong, Xujiao Zhou et al. from Fudan University find that somatostatin ameliorates corneal nerve abnormalities and inflammation through regulation of macrophage activities in dry eye disease.
doi.org/10.1167/iovs.66.14.18
doi.org/10.1167/iovs.66.14.18
November 7, 2025 at 5:03 PM
Jiaxu Hong, Xujiao Zhou et al. from Fudan University find that somatostatin ameliorates corneal nerve abnormalities and inflammation through regulation of macrophage activities in dry eye disease.
doi.org/10.1167/iovs.66.14.18
doi.org/10.1167/iovs.66.14.18
Li Jia Chen et al. from The Chinese University of Hong Kong investigate the combined effects of biological age acceleration and genetic risk on age-related eye diseases and blindness, and explored shared genetic pathways and potential anti-aging targets
doi.org/10.1167/iovs.66.14.14
doi.org/10.1167/iovs.66.14.14
November 6, 2025 at 3:25 PM
Li Jia Chen et al. from The Chinese University of Hong Kong investigate the combined effects of biological age acceleration and genetic risk on age-related eye diseases and blindness, and explored shared genetic pathways and potential anti-aging targets
doi.org/10.1167/iovs.66.14.14
doi.org/10.1167/iovs.66.14.14
Dongsheng Yan et al. from Wenzhou Medical University explore targeting miR-184 to enhance corneal epithelial wound healing.
doi.org/10.1167/iovs.66.14.13
doi.org/10.1167/iovs.66.14.13
November 6, 2025 at 3:25 PM
Dongsheng Yan et al. from Wenzhou Medical University explore targeting miR-184 to enhance corneal epithelial wound healing.
doi.org/10.1167/iovs.66.14.13
doi.org/10.1167/iovs.66.14.13
Arda Fidanci et al . from the University of Minnesota investigate the preferred retinal locus for reading in central vision loss.
doi.org/10.1167/iovs.66.14.12
doi.org/10.1167/iovs.66.14.12
November 6, 2025 at 3:24 PM
Arda Fidanci et al . from the University of Minnesota investigate the preferred retinal locus for reading in central vision loss.
doi.org/10.1167/iovs.66.14.12
doi.org/10.1167/iovs.66.14.12
Huifang Zhou, Jing Sun et al from Shanghai Ninth People's Hospital use high-throughput tear proteomics to reveals multi-faceted signatures of thyroid eye disease.
doi.org/10.1167/iovs.66.14.11
doi.org/10.1167/iovs.66.14.11
November 6, 2025 at 3:24 PM
Huifang Zhou, Jing Sun et al from Shanghai Ninth People's Hospital use high-throughput tear proteomics to reveals multi-faceted signatures of thyroid eye disease.
doi.org/10.1167/iovs.66.14.11
doi.org/10.1167/iovs.66.14.11
Taiji Nagaoka et al from Asahikawa Medical University find that dipeptidyl peptidase 4, a novel adipokine, impairs retinal microcirculation in patients with type 2 diabetes mellitus.
doi.org/10.1167/iovs.66.14.4
doi.org/10.1167/iovs.66.14.4
November 3, 2025 at 7:24 PM
Taiji Nagaoka et al from Asahikawa Medical University find that dipeptidyl peptidase 4, a novel adipokine, impairs retinal microcirculation in patients with type 2 diabetes mellitus.
doi.org/10.1167/iovs.66.14.4
doi.org/10.1167/iovs.66.14.4
Amir H. Kashani et al. from the Wilmer Eye Institute @HopkinsMedicine evaluate the relationship between retinal vascular density and retinal thickness (RT) using optical coherence tomography angiography (OCTA) in subjects with diabetic retinopathy.
doi.org/10.1167/iovs.66.14.3
doi.org/10.1167/iovs.66.14.3
November 3, 2025 at 7:24 PM
Amir H. Kashani et al. from the Wilmer Eye Institute @HopkinsMedicine evaluate the relationship between retinal vascular density and retinal thickness (RT) using optical coherence tomography angiography (OCTA) in subjects with diabetic retinopathy.
doi.org/10.1167/iovs.66.14.3
doi.org/10.1167/iovs.66.14.3
Brian G. Ballios et al. from the University of Toronto establish a human model of USH2A RP using retinal organoids derived from patient induced pluripotent stem cells and CRISPR-Cas9-engineered isogenic-USH2A−/− induced pluripotent stem cells.
doi.org/10.1167/iovs.66.14.2
doi.org/10.1167/iovs.66.14.2
November 3, 2025 at 7:23 PM
Brian G. Ballios et al. from the University of Toronto establish a human model of USH2A RP using retinal organoids derived from patient induced pluripotent stem cells and CRISPR-Cas9-engineered isogenic-USH2A−/− induced pluripotent stem cells.
doi.org/10.1167/iovs.66.14.2
doi.org/10.1167/iovs.66.14.2
Ula V. Jurkunas et al. from Schepens Eye Research Institute find that permanent senescence via p16 leads to guttae formation in an in vitro human corneal endothelial cell model.
doi.org/10.1167/iovs.66.14.1
doi.org/10.1167/iovs.66.14.1
November 3, 2025 at 7:22 PM
Ula V. Jurkunas et al. from Schepens Eye Research Institute find that permanent senescence via p16 leads to guttae formation in an in vitro human corneal endothelial cell model.
doi.org/10.1167/iovs.66.14.1
doi.org/10.1167/iovs.66.14.1
Bingyao Tan et al. from the Singapore Eye Research Institute report high-resolution optical phenotyping of retinal structure and microvasculature after optic nerve crush (ONC) in the mouse using speckle-reduced visible light optical coherence tomography
doi.org/10.1167/iovs.66.13.56
doi.org/10.1167/iovs.66.13.56
October 31, 2025 at 1:40 PM
Bingyao Tan et al. from the Singapore Eye Research Institute report high-resolution optical phenotyping of retinal structure and microvasculature after optic nerve crush (ONC) in the mouse using speckle-reduced visible light optical coherence tomography
doi.org/10.1167/iovs.66.13.56
doi.org/10.1167/iovs.66.13.56
New Perspective article by Thu Nga Nguyen, Louise Terry & Jeremy Guggenheim from Cardiff University examines whether the choice of genome-wide association study summary statistics can yield invalid or misleading conclusions in Mendelian randomization studies of myopia.
doi.org/10.1167/iovs.66.13.57
doi.org/10.1167/iovs.66.13.57
October 31, 2025 at 1:40 PM
New Perspective article by Thu Nga Nguyen, Louise Terry & Jeremy Guggenheim from Cardiff University examines whether the choice of genome-wide association study summary statistics can yield invalid or misleading conclusions in Mendelian randomization studies of myopia.
doi.org/10.1167/iovs.66.13.57
doi.org/10.1167/iovs.66.13.57
Anna Kosovicheva et al. from the University of Toronto investigate intact perceptual interactions of interocular temporal phase and contrast disparities in amblyopia.
doi.org/10.1167/iovs.66.13.55
doi.org/10.1167/iovs.66.13.55
October 30, 2025 at 5:09 PM
Anna Kosovicheva et al. from the University of Toronto investigate intact perceptual interactions of interocular temporal phase and contrast disparities in amblyopia.
doi.org/10.1167/iovs.66.13.55
doi.org/10.1167/iovs.66.13.55
Carole Peyrin et al. from the University of Grenoble Alpes investigate neurobehavioral changes in macular degeneration.
doi.org/10.1167/iovs.66.13.54
doi.org/10.1167/iovs.66.13.54
October 30, 2025 at 5:09 PM
Carole Peyrin et al. from the University of Grenoble Alpes investigate neurobehavioral changes in macular degeneration.
doi.org/10.1167/iovs.66.13.54
doi.org/10.1167/iovs.66.13.54
Raman Prasad Sah, Dawn Meyer & Pete Kollbaum from the Indiana University School of Optometry investigate the dynamic characteristics of accommodative behavior in non-myopic and myopic young adults under prolonged viewing of electronic devices.
doi.org/10.1167/iovs.66.13.53
doi.org/10.1167/iovs.66.13.53
October 30, 2025 at 5:08 PM
Raman Prasad Sah, Dawn Meyer & Pete Kollbaum from the Indiana University School of Optometry investigate the dynamic characteristics of accommodative behavior in non-myopic and myopic young adults under prolonged viewing of electronic devices.
doi.org/10.1167/iovs.66.13.53
doi.org/10.1167/iovs.66.13.53
Marzena Gajecka et al. from the Polish Academy of Sciences find that inter-eye molecular discrepancies in the corneal epithelium point to TFRC in the keratoconus severity signature and mechanism of cone formation.
doi.org/10.1167/iovs.66.13.52
doi.org/10.1167/iovs.66.13.52
October 29, 2025 at 1:40 PM
Marzena Gajecka et al. from the Polish Academy of Sciences find that inter-eye molecular discrepancies in the corneal epithelium point to TFRC in the keratoconus severity signature and mechanism of cone formation.
doi.org/10.1167/iovs.66.13.52
doi.org/10.1167/iovs.66.13.52
Jonathan L. Haines from Case Western Reserve University, Iris M. Heid from the University of Regensburg et al. perform a diverse-ancestry genome-wide association study of age-related macular degeneration on 16,108 examined cases and 18,038 controls.
doi.org/10.1167/iovs.66.13.51
doi.org/10.1167/iovs.66.13.51
October 29, 2025 at 1:40 PM
Jonathan L. Haines from Case Western Reserve University, Iris M. Heid from the University of Regensburg et al. perform a diverse-ancestry genome-wide association study of age-related macular degeneration on 16,108 examined cases and 18,038 controls.
doi.org/10.1167/iovs.66.13.51
doi.org/10.1167/iovs.66.13.51
Thomas Ach et al. from University Hospital Bonn use super-resolution near-infrared autofluorescence microscopy to depict melanin containing organelles of the retinal pigment epithelium in human donor eyes.
doi.org/10.1167/iovs.66.13.50
doi.org/10.1167/iovs.66.13.50
October 29, 2025 at 1:39 PM
Thomas Ach et al. from University Hospital Bonn use super-resolution near-infrared autofluorescence microscopy to depict melanin containing organelles of the retinal pigment epithelium in human donor eyes.
doi.org/10.1167/iovs.66.13.50
doi.org/10.1167/iovs.66.13.50
Vincent Daien et al. find that Temporal Analysis of Tear Fluid Proteome Reveals Critical Corneal Repair Events After Photorefractive Surgery, iovs.arvojournals.org/article.aspx....
October 28, 2025 at 2:43 PM
Vincent Daien et al. find that Temporal Analysis of Tear Fluid Proteome Reveals Critical Corneal Repair Events After Photorefractive Surgery, iovs.arvojournals.org/article.aspx....
Rajiv R. Mohan et al. report that Single-Cell Transcriptomics Shows Cellular Heterogeneity, Intercellular Communication, and Extracellular Matrix Remodeling in Corneal Fibrosis In Vivo, iovs.arvojournals.org/article.aspx....
October 28, 2025 at 2:38 PM
Rajiv R. Mohan et al. report that Single-Cell Transcriptomics Shows Cellular Heterogeneity, Intercellular Communication, and Extracellular Matrix Remodeling in Corneal Fibrosis In Vivo, iovs.arvojournals.org/article.aspx....
Vivek Singh et al. share their work Assessing the Independent and Combined Effects of Hyperosmolarity and Inflammatory Stress on Human Corneal Epithelial Cells, iovs.arvojournals.org/article.aspx....
October 28, 2025 at 2:31 PM
Vivek Singh et al. share their work Assessing the Independent and Combined Effects of Hyperosmolarity and Inflammatory Stress on Human Corneal Epithelial Cells, iovs.arvojournals.org/article.aspx....
In a new Perspective, Artur Cideciyan et al. discuss Location and Identity of Photoreceptors Contributing to the Full-Field Stimulus Test (FST), iovs.arvojournals.org/article.aspx....
October 28, 2025 at 2:28 PM
In a new Perspective, Artur Cideciyan et al. discuss Location and Identity of Photoreceptors Contributing to the Full-Field Stimulus Test (FST), iovs.arvojournals.org/article.aspx....
New in the Ocular Oncology Issue bit.ly/3VWoxXG, Piotr Donizy et al. study the Dualistic Role of MITF in Uveal Melanoma: Defining Two Distinct Cellular Subpopulations With Prognostic and Therapeutic Implications, iovs.arvojournals.org/article.aspx....
October 28, 2025 at 2:23 PM
New in the Ocular Oncology Issue bit.ly/3VWoxXG, Piotr Donizy et al. study the Dualistic Role of MITF in Uveal Melanoma: Defining Two Distinct Cellular Subpopulations With Prognostic and Therapeutic Implications, iovs.arvojournals.org/article.aspx....
Mahesh R. Joshi et al. from the University of Plymouth investigate deficits in motion and form perception in infantile nystagmus syndrome.
doi.org/10.1167/iovs.66.13.44
doi.org/10.1167/iovs.66.13.44
October 27, 2025 at 2:34 PM
Mahesh R. Joshi et al. from the University of Plymouth investigate deficits in motion and form perception in infantile nystagmus syndrome.
doi.org/10.1167/iovs.66.13.44
doi.org/10.1167/iovs.66.13.44
Tsz Wing Leung et al. from The Hong Kong Polytechnic University investigate whether localized retinal exposure to astigmatic blur is sufficient to drive compensatory changes in refractive and corneal astigmatism in developing chick eyes.
doi.org/10.1167/iovs.66.13.43
doi.org/10.1167/iovs.66.13.43
October 27, 2025 at 2:33 PM
Tsz Wing Leung et al. from The Hong Kong Polytechnic University investigate whether localized retinal exposure to astigmatic blur is sufficient to drive compensatory changes in refractive and corneal astigmatism in developing chick eyes.
doi.org/10.1167/iovs.66.13.43
doi.org/10.1167/iovs.66.13.43
SriniVas R. Sadda et al. from Doheny Eye Institute compare total RPE thickness and normalized reflectivity intensity on optical coherence tomography among healthy aged and early AMD (eAMD) and intermediate AMD eyes, and to visual function.
doi.org/10.1167/iovs.66.13.42
doi.org/10.1167/iovs.66.13.42
October 27, 2025 at 2:32 PM
SriniVas R. Sadda et al. from Doheny Eye Institute compare total RPE thickness and normalized reflectivity intensity on optical coherence tomography among healthy aged and early AMD (eAMD) and intermediate AMD eyes, and to visual function.
doi.org/10.1167/iovs.66.13.42
doi.org/10.1167/iovs.66.13.42