Armin Töpfer
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armintoepfer.com
Armin Töpfer
@armintoepfer.com
Husband. Parent. Dr sc @ETH. Bioinformagician. Father of @PacBio HiFi. C++ Purist. Geek. Digital Artist. Electronic music. Speaks in memes. Opinions are my own!
look at github.com/PacificBiosc... to get a better idea. We are not longer pushing to GH, but it's still in a good shape
GitHub - PacificBiosciences/pbbam: PacBio BAM C++ library
PacBio BAM C++ library. Contribute to PacificBiosciences/pbbam development by creating an account on GitHub.
github.com
March 15, 2025 at 7:22 PM
Yeah, but those are tricks to make mm2 faster. I'm thinking of a completely new approach that might be 10-100x faster.

It needs to span larger SVs and handle Q10-Q40 reads.

I don't have the answer.

What I have is a superior ksw2 GPU implementation, but it's closed source.
December 4, 2024 at 10:05 PM
Literally one minute.
November 28, 2024 at 9:03 PM
What a banger of a disc print.
November 23, 2024 at 7:30 PM