Ari Caroline
@aricaroline.bsky.social
Cofounder & CEO of https://www.weave.bio/. Former Chief Analytics Officer at Memorial Sloan Kettering. Torah, science, complexity and emergence. In search of the universe’s objective function.
Reposted by Ari Caroline
Successful programming is like evolution by RNA transcription error crossed with Bob Ross. Happy Little Accidents that become features.
June 19, 2025 at 6:46 PM
Successful programming is like evolution by RNA transcription error crossed with Bob Ross. Happy Little Accidents that become features.
Reposted by Ari Caroline
Rewiring, Not Retiring: For the "Vanguard Generation" (50+), hitting fifty isn't an inflection point-it's full steam ahead. They grew up w tech-enabled agency & expect products, services tailored for their reality - an underappreciated opportunity. My latest: timmermanreport.com/2025/02/rewi...
Rewiring, Not Retiring: Health and Innovation for the Vanguard Generation - TimmermanReport.com
Most of my columns tend to focus on the importance and difficulty of applying emerging technologies to biopharma R&D, aiming to accelerate the delivery of impactful medicines to patients. Yet, as lon...
timmermanreport.com
February 25, 2025 at 2:08 AM
Rewiring, Not Retiring: For the "Vanguard Generation" (50+), hitting fifty isn't an inflection point-it's full steam ahead. They grew up w tech-enabled agency & expect products, services tailored for their reality - an underappreciated opportunity. My latest: timmermanreport.com/2025/02/rewi...
“For the biopharma-focused readers of TR, the Open Evidence example serves as a vivid reminder that things don’t change — until they suddenly do.”
Woah - just saw this about latest raise from AI health unicorn (apparently), Open Evidence (h/t Matthew Holt): www.cnbc.com/2025/02/19/a... . My recent Timmerman Report on this topic -> timmermanreport.com/2024/10/and-...
AI health-care startup OpenEvidence raises funding from Sequoia at $1 billion valuation
The new $75 million cash injection values OpenEvidence at $1 billion, the two companies told CNBC.
www.cnbc.com
February 24, 2025 at 9:07 PM
“For the biopharma-focused readers of TR, the Open Evidence example serves as a vivid reminder that things don’t change — until they suddenly do.”
Reposted by Ari Caroline
Woah - just saw this about latest raise from AI health unicorn (apparently), Open Evidence (h/t Matthew Holt): www.cnbc.com/2025/02/19/a... . My recent Timmerman Report on this topic -> timmermanreport.com/2024/10/and-...
AI health-care startup OpenEvidence raises funding from Sequoia at $1 billion valuation
The new $75 million cash injection values OpenEvidence at $1 billion, the two companies told CNBC.
www.cnbc.com
February 24, 2025 at 7:24 PM
Woah - just saw this about latest raise from AI health unicorn (apparently), Open Evidence (h/t Matthew Holt): www.cnbc.com/2025/02/19/a... . My recent Timmerman Report on this topic -> timmermanreport.com/2024/10/and-...
+1
In Praise of Sankey Charts
Lest it seem like I'm just going to criticize people's figures & slides, I want to take a moment to salute a beautifully clear, helpful figure called a Sankey chart. It's tailor-made for showing how resources (here, pts) get distributed over time/treatment.
(1 of 2)
Lest it seem like I'm just going to criticize people's figures & slides, I want to take a moment to salute a beautifully clear, helpful figure called a Sankey chart. It's tailor-made for showing how resources (here, pts) get distributed over time/treatment.
(1 of 2)
December 10, 2024 at 1:16 AM
+1
Reposted by Ari Caroline
I sometimes forget how flexible proteins are. It becomes really apparent when you use NMR states for an animation. That poor cofactor is getting pushed around a lot 😅
#sciart #blender3d #biocatalysis
#sciart #blender3d #biocatalysis
November 25, 2024 at 5:14 PM
I sometimes forget how flexible proteins are. It becomes really apparent when you use NMR states for an animation. That poor cofactor is getting pushed around a lot 😅
#sciart #blender3d #biocatalysis
#sciart #blender3d #biocatalysis
Would LC + mass spec be overkill to quantify levels of quercetin molecules in different wines? @seamus.bsky.social , ready for a new project?
I’m quite certain, btw, that we’d find elevated quercetin levels in scotch (particularly Islay) as well. Bourbon, otoh, is completely fine for me.
I’m quite certain, btw, that we’d find elevated quercetin levels in scotch (particularly Islay) as well. Bourbon, otoh, is completely fine for me.
For those of us who have been suffering with red wine headaches for years and years, this study offers potential validation.
We all knew it wasn’t the sulfites!
Now I just need a study confirming that Merlot grapes are absolutely laced with quercetin glucuronide…
www.nature.com/articles/s41...
We all knew it wasn’t the sulfites!
Now I just need a study confirming that Merlot grapes are absolutely laced with quercetin glucuronide…
www.nature.com/articles/s41...
Inhibition of ALDH2 by quercetin glucuronide suggests a new hypothesis to explain red wine headaches - Scientific Reports
Scientific Reports - Inhibition of ALDH2 by quercetin glucuronide suggests a new hypothesis to explain red wine headaches
www.nature.com
November 26, 2024 at 2:59 AM
Would LC + mass spec be overkill to quantify levels of quercetin molecules in different wines? @seamus.bsky.social , ready for a new project?
I’m quite certain, btw, that we’d find elevated quercetin levels in scotch (particularly Islay) as well. Bourbon, otoh, is completely fine for me.
I’m quite certain, btw, that we’d find elevated quercetin levels in scotch (particularly Islay) as well. Bourbon, otoh, is completely fine for me.
For those of us who have been suffering with red wine headaches for years and years, this study offers potential validation.
We all knew it wasn’t the sulfites!
Now I just need a study confirming that Merlot grapes are absolutely laced with quercetin glucuronide…
www.nature.com/articles/s41...
We all knew it wasn’t the sulfites!
Now I just need a study confirming that Merlot grapes are absolutely laced with quercetin glucuronide…
www.nature.com/articles/s41...
Inhibition of ALDH2 by quercetin glucuronide suggests a new hypothesis to explain red wine headaches - Scientific Reports
Scientific Reports - Inhibition of ALDH2 by quercetin glucuronide suggests a new hypothesis to explain red wine headaches
www.nature.com
November 26, 2024 at 2:41 AM
For those of us who have been suffering with red wine headaches for years and years, this study offers potential validation.
We all knew it wasn’t the sulfites!
Now I just need a study confirming that Merlot grapes are absolutely laced with quercetin glucuronide…
www.nature.com/articles/s41...
We all knew it wasn’t the sulfites!
Now I just need a study confirming that Merlot grapes are absolutely laced with quercetin glucuronide…
www.nature.com/articles/s41...
Dammit @seanmcarroll.bsky.social
I had resolved to limit this new bluesky account to medicine, science, machine learning and complexity.
“Let me see who Sean Carroll is following…”
I’m now following 3 different Sixers reporters. :/
I had resolved to limit this new bluesky account to medicine, science, machine learning and complexity.
“Let me see who Sean Carroll is following…”
I’m now following 3 different Sixers reporters. :/
November 19, 2024 at 2:52 AM
Dammit @seanmcarroll.bsky.social
I had resolved to limit this new bluesky account to medicine, science, machine learning and complexity.
“Let me see who Sean Carroll is following…”
I’m now following 3 different Sixers reporters. :/
I had resolved to limit this new bluesky account to medicine, science, machine learning and complexity.
“Let me see who Sean Carroll is following…”
I’m now following 3 different Sixers reporters. :/