April Hayes
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aprilhayes.bsky.social
April Hayes
@aprilhayes.bsky.social
(she/her) postdoc @ Uni of Exeter in Cornwall 🌊mainly stress out bacteria and track AMR. big fan of the sea, reading, & sunsets 🌞
Reposted by April Hayes
Our contribution to this special issue: a review on data analysis of human gut microbiome data from global populations

www.cell.com/trends/micro...
Analyzing human gut microbiome data from global populations: challenges and resources
Research on the human gut microbiome is expanding rapidly; yet, most published studies focus on populations from high-income regions such as North America and Europe. Underrepresentation of population...
www.cell.com
November 12, 2025 at 2:13 AM
I’m so glad they got there safely!! 💛
November 11, 2025 at 1:00 PM
TLDR - mixtures including non-antibiotic drugs can alter selection for AMR, and we should not only consider compounds that show effects in isolation, when in mixtures, they might enhance the effects of antibiotics
October 14, 2025 at 2:00 PM
3) there were also alterations to the community composition after this seven day period.

most interestingly - these NADs had not had any similar effects when tested individually, but when they were combined with ciprofloxacin they enhanced the selective effect of ciprofloxacin
October 14, 2025 at 2:00 PM
2) we found that the addition of 1 NAD to ciprofloxacin increased the inhibitory effects on growth over a 12 hour period.

we also did some longer experiments, and exposed the community to ciprofloxacin and 1 NAD for seven days. after this, the selection dynamics for several ARGs were altered
October 14, 2025 at 2:00 PM