Daria Amiad Pavlov
@apdaria.bsky.social
Assistant Professor, Faculty of Medicine Technion IIT. Studying nuclear mechanobiology in the cardiac and skeletal muscle.
It is finally out! Updated with exciting in-vivo microtubule disruption results to protect Lmna deficient nuclei from damage. My final postdoc project with Prosser Lab and a great collaboration with @lammerdinglab.bsky.social, Shenoy Lab, and Jain lab.
Research | Amiad Pavlov, Heffler et al. demonstrate that stress transmitted to the cardiomyocyte nucleus by the microtubule cage drives LMNA-associated cardiomyopathy and may represent a promising therapeutic target.
doi.org/10.1038/s441...
rdcu.be/eOeTA
doi.org/10.1038/s441...
rdcu.be/eOeTA
Microtubule forces drive nuclear damage in LMNA cardiomyopathy - Nature Cardiovascular Research
Amiad Pavlov, Heffler, et al. demonstrate that stress transmitted to the cardiomyocyte nucleus by the microtubule cage drives LMNA-associated cardiomyopathy and may represent a promising therapeutic t...
doi.org
November 6, 2025 at 1:26 PM
It is finally out! Updated with exciting in-vivo microtubule disruption results to protect Lmna deficient nuclei from damage. My final postdoc project with Prosser Lab and a great collaboration with @lammerdinglab.bsky.social, Shenoy Lab, and Jain lab.
Reposted by Daria Amiad Pavlov
Quantifying cardiomyocyte contraction & nuclear deformation interaction reveals nucleus-damaging mechanism underlying LMNA cardiomyopathy
📷 @apdaria.bsky.social & Julie Heffler et al @weillcornell.bsky.social @pennmedicine.bsky.social
in @natcardiovascres.nature.com
➡️ bpod.org.uk/archive/2025...
📷 @apdaria.bsky.social & Julie Heffler et al @weillcornell.bsky.social @pennmedicine.bsky.social
in @natcardiovascres.nature.com
➡️ bpod.org.uk/archive/2025...
October 29, 2025 at 11:07 AM
Quantifying cardiomyocyte contraction & nuclear deformation interaction reveals nucleus-damaging mechanism underlying LMNA cardiomyopathy
📷 @apdaria.bsky.social & Julie Heffler et al @weillcornell.bsky.social @pennmedicine.bsky.social
in @natcardiovascres.nature.com
➡️ bpod.org.uk/archive/2025...
📷 @apdaria.bsky.social & Julie Heffler et al @weillcornell.bsky.social @pennmedicine.bsky.social
in @natcardiovascres.nature.com
➡️ bpod.org.uk/archive/2025...
Reposted by Daria Amiad Pavlov
Join us for the first Mechanobiology of the Nucleus conference supported by @faseborg.bsky.social. Co-organized with @lammerdinglab.bsky.social, @katemiro.bsky.social and Verena Ruprecht, the amazing program is here:
events.faseb.org/event/Mechan...
Opportunities for talks! Abstracts by Aug. 31st.
events.faseb.org/event/Mechan...
Opportunities for talks! Abstracts by Aug. 31st.
July 21, 2025 at 1:14 AM
Join us for the first Mechanobiology of the Nucleus conference supported by @faseborg.bsky.social. Co-organized with @lammerdinglab.bsky.social, @katemiro.bsky.social and Verena Ruprecht, the amazing program is here:
events.faseb.org/event/Mechan...
Opportunities for talks! Abstracts by Aug. 31st.
events.faseb.org/event/Mechan...
Opportunities for talks! Abstracts by Aug. 31st.