This research, published in the @thelancet.bsky.social Oncology, was led by Hend Hassan, a PhD student at the Centre for @ccge-cambridge.bsky.social @dphpc.bsky.social.

Read more: crukcambridgecentre.org.uk/news/removin...

Yes v important question! Unfortunately the linked prescriptions dataset was only available from 2015 onwards and in fact there was a very small number of carriers who received hrt. The numbers did not allow for adjustments in the analysis or for stratified analysis by hrt.

See also:
🗞️ Press release: www.cam.ac.uk/research/new...

🖊️ Editorial: www.thelancet.com/journals/lan...

Great team effort across @dphpc.bsky.social, @cambridgeuni.bsky.social @crukcamcentre.bsky.social the CanGene-CanVar programme, NHS England’s National Disease Registration Service. Huge thanks to all involved. Funded by @cancerresearchuk.org

Based on linking national cancer registry, hospital records, and genetic testing data — a major step forward in evaluating preventive surgery in high-risk groups.

✅ Key findings:
• BSO associated with lower all-cause & breast cancer-specific mortality
• No increased risk for CVD, ischaemic heart disease, cerebrovascular disease, or depression
• Lower uptake of BSO among Black & Asian women → highlighting disparities in access/decision-making