Anne-Sophie Pepin
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annesopepin.bsky.social
Anne-Sophie Pepin
@annesopepin.bsky.social
MSCA Postdoc fellow in Epigenetics at Helmholtz Munich | BSc & PhD in Pharmacology at McGill University | she/her
Reposted by Anne-Sophie Pepin
Our latest collaboration with @rongfan8.bsky.social, spatial triomics to investigate myelin and cortical brain development, and demyelination, spearheaded by Leslie Kirby in our lab @ki.se and Di Zhang in Rong's lab! Check it out @nature.com

www.nature.com/articles/s41...
Spatial dynamics of brain development and neuroinflammation - Nature
A tri-omic atlas of the mouse brain from postnatal day 0 to P21 reveals that layer-specific projection neurons have a role in coordinating axonogenesis and myelination.
www.nature.com
November 5, 2025 at 4:03 PM
Reposted by Anne-Sophie Pepin
Epigenetics Update - Spatial dynamics of brain development and neuroinflammation go.nature.com/49AJu3Q

Gonçalo Castelo-Branco and Rong Fan reporting in Nature

#Epigenetics #Multiomics #BrainDevelopment #Neuroinflammation

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Discover the breakthrough at epigenometech.com
November 6, 2025 at 8:16 AM
Reposted by Anne-Sophie Pepin
#Jobalert 🚨: Please RT !
Looking for a #PhD student for exciting project on the interphase between epigenetics and cellular metabolism:
How do (nuclear) metabolic enzymes reguate chromatin function ?
#epigenomics, #epigenetics, #metabolism
www.helmholtz-munich.de/en/ife/job-o...
September 22, 2025 at 2:22 PM
Reposted by Anne-Sophie Pepin
Best first bsky post posible 4us:

2025 INTERNSHIP CALL IS NOW OPEN!

Ready for an adventure this summer?

Join our 2025 #Epigenetics #SummerInternship at Helmholtz Munich! Dive into AI, stem cells, nutrition and cutting-edge research, while gaining hands-on experience.

Apply now! 👉 bit.ly/40g1BWL
January 15, 2025 at 2:18 PM
Reposted by Anne-Sophie Pepin
How to do differential expression with scRNAseq data? State of the art is "pseudo-bulk" analysis with RNA-seq methods like edgeR or DESeq2, where "cell type" is encoded as discrete categories. Biologically, discrete categories are not always the most appropriate concept.(1/3)
doi.org/10.1038/s415...
Analysis of multi-condition single-cell data with latent embedding multivariate regression - Nature Genetics
Latent embedding multivariate regression models multi-condition single-cell RNA-seq using a continuous latent space, enabling data integration, per-cell gene expression prediction and clustering-free ...
doi.org
January 3, 2025 at 7:18 PM