AnnaLin Woo
@annalinwoo.bsky.social
Neuroscientist | Passionate about science communication and lifelong learning | I 🖤 perineuronal nets | Astrocytes are Awesome | #epilepsyawareness
One of UVA's clinician researchers is also heading up a big grant looking at using ketamine as seizure treatment newsroom.uvahealth.com/2025/01/29/c...
I wish I had more & better info for you. Do you have any local communities or groups that you can lean on as well?
I wish I had more & better info for you. Do you have any local communities or groups that you can lean on as well?
Can Ketamine Stop Deadly Epilepsy Seizures?
UVA has received $9.3 million to test if ketamine can save patients from grand mal seizures that won’t respond to other treatments.
newsroom.uvahealth.com
July 7, 2025 at 7:37 PM
One of UVA's clinician researchers is also heading up a big grant looking at using ketamine as seizure treatment newsroom.uvahealth.com/2025/01/29/c...
I wish I had more & better info for you. Do you have any local communities or groups that you can lean on as well?
I wish I had more & better info for you. Do you have any local communities or groups that you can lean on as well?
That is incredibly rough, I am sorry to hear it. I know Mayo Clinic has been working on some regenerative therapy techniques that they are hopeful about: newsnetwork.mayoclinic.org/discussion/m...
newsnetwork.mayoclinic.org
July 7, 2025 at 7:36 PM
That is incredibly rough, I am sorry to hear it. I know Mayo Clinic has been working on some regenerative therapy techniques that they are hopeful about: newsnetwork.mayoclinic.org/discussion/m...
...a bit of a "chicken vs egg" question!
You can find this open-access article here: doi.org/10.1111/epi....
Many thanks to my co-authors and all of the supportive folks that have been involved!
#epilepsy #epilepsia #ecm #matrix #perineuronalnets #pnns #neuroscience
(5/5)
You can find this open-access article here: doi.org/10.1111/epi....
Many thanks to my co-authors and all of the supportive folks that have been involved!
#epilepsy #epilepsia #ecm #matrix #perineuronalnets #pnns #neuroscience
(5/5)
Contribution of perineuronal nets to hyperexcitability in pilocarpine‐induced status epilepticus
Objective Changes in extracellular matrix (ECM) and highly condensed ECM structures called perineuronal nets (PNNs) have been reported in human patients with epilepsy as well as some animal models o...
doi.org
July 2, 2025 at 8:18 PM
...a bit of a "chicken vs egg" question!
You can find this open-access article here: doi.org/10.1111/epi....
Many thanks to my co-authors and all of the supportive folks that have been involved!
#epilepsy #epilepsia #ecm #matrix #perineuronalnets #pnns #neuroscience
(5/5)
You can find this open-access article here: doi.org/10.1111/epi....
Many thanks to my co-authors and all of the supportive folks that have been involved!
#epilepsy #epilepsia #ecm #matrix #perineuronalnets #pnns #neuroscience
(5/5)
Interneurons are the "brakes" of the brain, balancing out excitatory activity. If they are are more active in our model, they could be forming nets to try to balance overexcitation, or the nets could be forming due to increased activity...
(4/5)
(4/5)
July 2, 2025 at 8:18 PM
Interneurons are the "brakes" of the brain, balancing out excitatory activity. If they are are more active in our model, they could be forming nets to try to balance overexcitation, or the nets could be forming due to increased activity...
(4/5)
(4/5)
... which can lead to future seizures and developing epilepsy, but exactly what happens is not fully known.
These interneurons developing new nets makes them more excitable in our model- so the neurons are firing more than w/o nets, which is both exciting and new!
(3/5)
These interneurons developing new nets makes them more excitable in our model- so the neurons are firing more than w/o nets, which is both exciting and new!
(3/5)
July 2, 2025 at 8:18 PM
... which can lead to future seizures and developing epilepsy, but exactly what happens is not fully known.
These interneurons developing new nets makes them more excitable in our model- so the neurons are firing more than w/o nets, which is both exciting and new!
(3/5)
These interneurons developing new nets makes them more excitable in our model- so the neurons are firing more than w/o nets, which is both exciting and new!
(3/5)
...a long and severe seizure episode called "status epilepticus". This matters a lot because as of right now, the process of developing epilepsy is still... well, sort of a black box!
We know there are changes going on in the brain after an injury...
(2/5)
We know there are changes going on in the brain after an injury...
(2/5)
July 2, 2025 at 8:17 PM
...a long and severe seizure episode called "status epilepticus". This matters a lot because as of right now, the process of developing epilepsy is still... well, sort of a black box!
We know there are changes going on in the brain after an injury...
(2/5)
We know there are changes going on in the brain after an injury...
(2/5)
I found an image of the notebook in this Guardian article, though I can't read it! www.theguardian.com/artanddesign...
The Da Vinci load: Leonardo's packing list revealed
Renaissance artist and anatomist needed pane of glass, forceps and a bone saw, a page from his notebook reveals
www.theguardian.com
April 3, 2025 at 5:38 PM
I found an image of the notebook in this Guardian article, though I can't read it! www.theguardian.com/artanddesign...
You do not need a lawyer to file your appeal. You must not delay filing because you want to find a lawyer to represent you – you will lose your claims if you do not file on or before the deadline. (4/4)
April 3, 2025 at 2:53 PM
You do not need a lawyer to file your appeal. You must not delay filing because you want to find a lawyer to represent you – you will lose your claims if you do not file on or before the deadline. (4/4)
Here is how you file an appeal www.mspb.gov/appeals/appe... And here is where you file an appeal online: e-appeal.mspb.gov/etk-mspb.../... (3/4)
U.S. Merit Systems Protection Board
MSPB Mission: To protect the Merit System Principles and promote an effective Federal workforce free of Prohibited Personnel Practices.
www.mspb.gov
April 3, 2025 at 2:53 PM
Here is how you file an appeal www.mspb.gov/appeals/appe... And here is where you file an appeal online: e-appeal.mspb.gov/etk-mspb.../... (3/4)
The time limit to appeal is 30 days from the effective date of your termination or the date you received the Agency’s decision, whichever is later. (2/3)
U.S. Merit Systems Protection Board
MSPB Mission: To protect the Merit System Principles and promote an effective Federal workforce free of Prohibited Personnel Practices.
www.mspb.gov
April 3, 2025 at 2:52 PM
The time limit to appeal is 30 days from the effective date of your termination or the date you received the Agency’s decision, whichever is later. (2/3)
A friend with a neuro BS went into nursing! Some went to grad school (me included); 1 went on to work as a counselor/ in social work (started with BS and went on to do a master's eventually); similarly another into gene therapy; & some went a completely different direction in coding & finance!
March 14, 2025 at 12:31 PM
A friend with a neuro BS went into nursing! Some went to grad school (me included); 1 went on to work as a counselor/ in social work (started with BS and went on to do a master's eventually); similarly another into gene therapy; & some went a completely different direction in coding & finance!
Reposted by AnnaLin Woo
We can beat them. That's the secret. The bluster now? All meant to keep you from realizing your own power and agency. end/
January 31, 2025 at 10:58 PM
We can beat them. That's the secret. The bluster now? All meant to keep you from realizing your own power and agency. end/