Anna Leder
@annaleder.bsky.social
PhD student in Hiller lab, University of Basel | studying molecular chaperones and protein folding homeostasis
Happy to share my first publication, where we present our discovery of multi-chaperone condensates that orchestrate protein folding in the endoplasmic reticulum!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 11, 2025 at 3:07 PM
Happy to share my first publication, where we present our discovery of multi-chaperone condensates that orchestrate protein folding in the endoplasmic reticulum!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Check out this amazing work on the functional cycle of Hsp70 BiP NBD at atomic resolution by @masgu.bsky.social
Introducing in-cyclo NMR, a breakthrough method led by first author @masgu.bsky.social at @biozentrum.unibas.ch! This method combines high-resolution NMR with ATP regeneration & phosphate removal to resolve kinetics & dynamics of molecular machines - all in one experiment! doi.org/10.1038/s414...
Mechanism of ATP hydrolysis in the Hsp70 BiP nucleotide-binding domain - Nature Communications
Mas et al introduce in-cyclo NMR to quantify all states and kinetic steps of Hsp70 chaperones ATPase cycle. In-cyclo NMR will enable studies of other molecular machines at an unprecedented level of de...
doi.org
June 2, 2025 at 2:38 PM
Check out this amazing work on the functional cycle of Hsp70 BiP NBD at atomic resolution by @masgu.bsky.social